Aliases for NAV2 Gene
Aliases for NAV2 Gene
External Ids for NAV2 Gene
- HGNC: 15997
- Entrez Gene: 89797
- Ensembl: ENSG00000166833
- OMIM: 607026
- UniProtKB: Q8IVL1
Previous GeneCards Identifiers for NAV2 Gene
- GC11P020896
- GC11P020678
- GC11P019411
- GC11P019699
- GC11P019691
- GC11P019056
- GC11P019372
- GC11P019353
Summaries for NAV2 Gene
-
This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for NAV2 Gene
NAV2 (Neuron Navigator 2) is a Protein Coding gene. Diseases associated with NAV2 include Neuroblastoma. Gene Ontology (GO) annotations related to this gene include heparin binding and helicase activity. An important paralog of this gene is NAV3.
UniProtKB/Swiss-Prot for NAV2 Gene
-
Possesses 3 to 5 helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs.
Additional gene information for NAV2 Gene
- Monarch Initiative
- Search for NAV2 at DataMed
- Search for NAV2 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NAV2 Gene
Genomics for NAV2 Gene
GeneHancer (GH) Regulatory Elements for NAV2 Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH11I019711 | Promoter/Enhancer | 2.4 | EPDnew FANTOM5 Ensembl ENCODE dbSUPER | 552.5 | +368.7 | 368657 | 5.6 | PKNOX1 SIN3A FEZF1 DMAP1 ZNF2 YY1 POLR2B ZNF766 ZNF213 FOS | NAV2 LOC100126784 ENSG00000207407 GC11M019646 | |
GH11I020021 | Promoter/Enhancer | 1.8 | EPDnew Ensembl ENCODE dbSUPER | 550 | +678.6 | 678573 | 4.9 | FOXA2 ZSCAN4 ARID4B MZF1 SIN3A FEZF1 ZNF48 RAD21 YY1 ZNF213 | GC11P020022 GC11P020023 NAV2 NAV2-AS3 GC11P020044 GC11M020007 | |
GH11I019344 | Enhancer | 1 | Ensembl ENCODE | 550.8 | +0.6 | 581 | 1.8 | PKNOX1 NFIB SIN3A ZNF2 RAD21 ZEB1 ZNF335 GLIS2 EGR1 FOS | NAV2 GC11P019352 GC11P019350 | |
GH11I019350 | Promoter | 0.5 | EPDnew | 550.4 | +5.5 | 5538 | 0.1 | GC11P019352 GC11P019350 NAV2 | ||
GH11I019365 | Enhancer | 0.9 | Ensembl ENCODE | 11.6 | +23.5 | 23456 | 5.6 | JUN MAX EBF1 YY1 CTBP1 GATA3 POLR2A FOS EZH2 HLF | NAV2 NAV2-AS5 NAV2-IT1 GC11P019352 GC11P019350 |
Regulatory Element Products
Genomic Locations for NAV2 Gene
- chr11:19,345,247-20,121,601
- (GRCh38/hg38)
- Size:
- 776,355 bases
- Orientation:
- Plus strand
- chr11:19,372,271-20,143,147
- (GRCh37/hg19)
Genomic View for NAV2 Gene
- Cytogenetic band:
-
- 11p15.1 by Ensembl
- 11p15.1 by Entrez Gene
- 11p15.1 by HGNC


RefSeq DNA sequence for NAV2 Gene
Proteins for NAV2 Gene
-
Protein details for NAV2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8IVL1-NAV2_HUMAN
- Recommended name:
- Neuron navigator 2
- Protein Accession:
- Q8IVL1
- A6NEC1
- Q8IVK3
- Q8IVK4
- Q8IVK5
- Q8IVK6
- Q8IVK7
- Q8IVK8
- Q8NHC9
- Q8NHD0
- Q8TDE9
- Q8TDF0
- Q8TEB3
- Q96B30
- Q9NUZ6
- Q9NVM7
- Q9P2C8
Protein attributes for NAV2 Gene
- Size:
- 2488 amino acids
- Molecular mass:
- 268167 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAA92657.3; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAB85038.1; Type=Frameshift; Positions=2074; Evidence={ECO:0000305};
Protein Expression for NAV2 Gene
Post-translational modifications for NAV2 Gene
Other Protein References for NAV2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- NP_001104488.1
- NP_001104489.1
- NP_001231892.1
- NP_660093.2
- NP_892009.3
- XP_005253271.1
- XP_006718427.1
- XP_006718428.1
- XP_006718429.1
- XP_006718430.1
- XP_006718431.1
- XP_006718432.1
- XP_011518746.1
- XP_011518747.1
- XP_011518748.1
- XP_011518749.1
- XP_011518750.1
- XP_011518751.1
- XP_011518752.1
- XP_011518753.1
- XP_011518754.1
- XP_011518755.1
- XP_011518756.1
- XP_016874009.1
- XP_016874010.1
- XP_016874011.1
- XP_016874012.1
- XP_016874013.1
- XP_016874014.1
- XP_016874015.1
Antibody Products
- Novus Biologicals Antibodies for NAV2
- Invitrogen Antibodies for NAV2
- GeneTex NAV2 antibody for NAV2
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for NAV2
- Origene Custom Protein Services for NAV2
- Search GeneTex for Proteins for NAV2
-
Abcam proteins for NAV2
Assay Products
- antibodies-online: Search results for available NAV2 related products ranked by validation data
No data available for DME Specific Peptides for NAV2 Gene
Domains & Families for NAV2 Gene
Gene Families for NAV2 Gene
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for NAV2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for NAV2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8IVL1- Family:
-
- Belongs to the Nav/unc-53 family.
Function for NAV2 Gene
Molecular function for NAV2 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- ATP + H(2)O = ADP + phosphate.
- UniProtKB/Swiss-Prot Function:
- Possesses 3 to 5 helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs.
- UniProtKB/Swiss-Prot Induction:
- By all-trans retinoic acid (ATRA). Up-regulated in colorectal carcinomas.
Enzyme Numbers (IUBMB) for NAV2 Gene
Phenotypes From GWAS Catalog for NAV2 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004386 | helicase activity | IEA | -- |
GO:0005515 | protein binding | IPI | 16189514 |
GO:0005524 | ATP binding | IEA | -- |
GO:0008201 | heparin binding | IEA | -- |
GO:0016787 | hydrolase activity | IEA | -- |
Phenotypes for NAV2 Gene
- MGI mutant phenotypes for NAV2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for NAV2:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for NAV2
-
-
ViGene Biosciences lentiviral particle packaged cDNA for NAV2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for NAV2 gene
- Search ViGene Biosciences for NAV2
CRISPR Products
-
OriGene CRISPR knockouts for NAV2
- genomics-online: gRNA clones - Search results for 91 available NAV2 gene related products
- Overview of 91 available NAV2 gene related products
- Applied Biological Materials CRISPR for NAV2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for NAV2
- GenScript: Design CRISPR guide RNA sequences for NAV2
miRNA for NAV2 Gene
- miRTarBase miRNAs that target NAV2
-
- hsa-mir-663a (MIRT006089)
- hsa-mir-98-5p (MIRT027632)
- hsa-mir-16-5p (MIRT051065)
- hsa-mir-6825-5p (MIRT472445)
- hsa-mir-7106-5p (MIRT472446)
- hsa-mir-765 (MIRT472447)
- hsa-mir-766-5p (MIRT472448)
- hsa-mir-3202 (MIRT472449)
- hsa-mir-3179 (MIRT472450)
- hsa-mir-6876-5p (MIRT472451)
- hsa-mir-4779 (MIRT472452)
- hsa-mir-4476 (MIRT472453)
- hsa-mir-6856-5p (MIRT472454)
- hsa-mir-6758-5p (MIRT472455)
- hsa-mir-6883-5p (MIRT483621)
- hsa-mir-6785-5p (MIRT483622)
- hsa-mir-4728-5p (MIRT483623)
- hsa-mir-149-3p (MIRT483624)
- hsa-mir-6797-5p (MIRT483625)
- hsa-mir-1249-5p (MIRT483626)
- hsa-mir-6133 (MIRT483627)
- hsa-mir-6130 (MIRT483628)
- hsa-mir-6129 (MIRT483629)
- hsa-mir-6127 (MIRT483630)
- hsa-mir-4510 (MIRT483631)
- hsa-mir-4419a (MIRT483632)
- hsa-mir-4756-5p (MIRT483633)
- hsa-mir-4739 (MIRT483634)
- hsa-mir-1321 (MIRT483635)
- hsa-mir-6835-3p (MIRT535699)
- hsa-mir-4668-5p (MIRT610718)
- hsa-mir-1298-5p (MIRT610719)
- hsa-mir-664a-3p (MIRT610720)
- hsa-mir-548z (MIRT610721)
- hsa-mir-548h-3p (MIRT610722)
- hsa-mir-548d-3p (MIRT610723)
- hsa-mir-548bb-3p (MIRT610724)
- hsa-mir-548ac (MIRT610725)
- hsa-mir-6809-3p (MIRT615671)
- hsa-mir-6833-3p (MIRT615672)
- hsa-mir-4768-5p (MIRT615673)
- hsa-mir-6759-5p (MIRT615674)
- hsa-mir-4753-3p (MIRT615675)
- hsa-mir-6873-3p (MIRT615676)
- hsa-mir-2117 (MIRT615677)
- hsa-mir-6793-5p (MIRT615678)
- hsa-mir-6748-5p (MIRT615679)
- hsa-mir-597-3p (MIRT615680)
- hsa-mir-23b-5p (MIRT615681)
- hsa-mir-23a-5p (MIRT615682)
- hsa-mir-130b-5p (MIRT615683)
- hsa-mir-6817-3p (MIRT615684)
- hsa-mir-7110-3p (MIRT615685)
- hsa-mir-299-3p (MIRT615686)
- hsa-mir-6818-3p (MIRT623140)
- hsa-mir-6888-3p (MIRT623141)
- hsa-mir-593-3p (MIRT623142)
- hsa-mir-6895-3p (MIRT623143)
- hsa-mir-3120-5p (MIRT623144)
- hsa-mir-335-3p (MIRT667262)
- hsa-mir-664b-3p (MIRT667263)
- hsa-mir-5696 (MIRT667264)
- hsa-mir-579-3p (MIRT667265)
- hsa-mir-627-3p (MIRT667266)
miRNA Products
- Search ViGene Biosciences for NAV2
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for NAV2
- Browse OriGene Inhibitory RNA Products For NAV2
- genomics-online: shRNA clones - Search results for 91 available NAV2 gene related products
- Overview of 91 available NAV2 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for NAV2 gene
Clone Products
-
GenScript: Next-day shipping of latest version cDNA ORF clones for NAV2 in any vector
- XM_011520451.1
- XM_006718368.2
- XM_011520453.1
- XM_011520444.1
- XM_006718365.2
- NM_001111019.2
- XM_011520448.1
- NM_145117.4
- XM_006718366.2
- XM_006718367.2
- XM_006718369.1
- NM_001244963.1
- XM_006718364.2
- XM_011520447.1
- NM_182964.5
- XM_011520450.1
- XM_011520452.1
- XM_005253214.3
- XM_011520454.1
- XM_011520445.1
- XM_011520446.1
- NM_001111018.1
- XM_011520449.1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for NAV2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NAV2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for NAV2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for NAV2
-
ViGene Biosciences adenoviral particle packaged cDNA for NAV2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for NAV2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for NAV2 gene
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NAV2 Gene
Localization for NAV2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for NAV2 Gene
- Nucleus.
- Nucleoplasm (3)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005578 | proteinaceous extracellular matrix | IEA | -- |
GO:0005614 | interstitial matrix | IEA | -- |
GO:0005634 | nucleus | IEA | -- |
GO:0005654 | nucleoplasm | IDA | -- |
Pathways & Interactions for NAV2 Gene
Interacting Proteins for NAV2 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003025 | regulation of systemic arterial blood pressure by baroreceptor feedback | IEA | -- |
GO:0007399 | nervous system development | IEA | -- |
GO:0007605 | sensory perception of sound | IEA | -- |
GO:0007608 | sensory perception of smell | IEA | -- |
GO:0007626 | locomotory behavior | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for NAV2 Gene
Drugs & Compounds for NAV2 Gene
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
---|---|---|---|---|---|---|
ADP |
|
Full agonist, Agonist | 58-64-0 |
|
Transcripts for NAV2 Gene
mRNA/cDNA for NAV2 Gene
- (30) REFSEQ mRNAs :
- (47) Selected AceView cDNA sequences:
- (16) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for NAV2
- genomics-online: gRNA clones - Search results for 91 available NAV2 gene related products
- Overview of 91 available NAV2 gene related products
- Applied Biological Materials CRISPR for NAV2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for NAV2
- GenScript: Design CRISPR guide RNA sequences for NAV2
miRNA Products
- Search ViGene Biosciences for NAV2
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for NAV2
- Browse OriGene Inhibitory RNA Products For NAV2
- genomics-online: shRNA clones - Search results for 91 available NAV2 gene related products
- Overview of 91 available NAV2 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for NAV2 gene
Clone Products
-
GenScript: Next-day shipping of latest version cDNA ORF clones for NAV2 in any vector
- XM_011520451.1
- XM_006718368.2
- XM_011520453.1
- XM_011520444.1
- XM_006718365.2
- NM_001111019.2
- XM_011520448.1
- NM_145117.4
- XM_006718366.2
- XM_006718367.2
- XM_006718369.1
- NM_001244963.1
- XM_006718364.2
- XM_011520447.1
- NM_182964.5
- XM_011520450.1
- XM_011520452.1
- XM_005253214.3
- XM_011520454.1
- XM_011520445.1
- XM_011520446.1
- NM_001111018.1
- XM_011520449.1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for NAV2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NAV2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for NAV2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25a | · |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP2: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
SP3: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP5: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP6: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP7: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP8: |
ExUns: | 25b | ^ | 26 | ^ | 27a | · | 27b | ^ | 28a | · | 28b |
---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||||
SP2: | |||||||||||
SP3: | |||||||||||
SP4: | - | ||||||||||
SP5: | |||||||||||
SP6: | |||||||||||
SP7: | |||||||||||
SP8: |
Expression for NAV2 Gene
mRNA differential expression in normal tissues according to GTEx for NAV2 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for NAV2 Gene
NURSA nuclear receptor signaling pathways regulating expression of NAV2 Gene:
NAV2SOURCE GeneReport for Unigene cluster for NAV2 Gene:
Hs.502116mRNA Expression by UniProt/SwissProt for NAV2 Gene:
Q8IVL1-NAV2_HUMANEvidence on tissue expression from TISSUES for NAV2 Gene
- Nervous system(4.8)
- Liver(4.2)
- Skin(4.2)
- Lung(2.1)
Primer Products
-
OriGene qPCR primer pairs for NAV2
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for NAV2 Gene
Orthologs for NAV2 Gene
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | NAV2 33 34 |
|
||
dog (Canis familiaris) |
Mammalia | NAV2 33 34 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | NAV2 34 |
|
OneToOne | |
cow (Bos Taurus) |
Mammalia | NAV2 33 34 |
|
||
platypus (Ornithorhynchus anatinus) |
Mammalia | NAV2 34 |
|
OneToOne | |
mouse (Mus musculus) |
Mammalia | Nav2 33 16 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | Nav2 33 |
|
||
chicken (Gallus gallus) |
Aves | NAV2 33 34 |
|
||
lizard (Anolis carolinensis) |
Reptilia | NAV2 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | nav2 33 |
|
||
Str.4535 33 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.34129 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | NAV2 (2 of 2) 34 |
|
OneToMany | |
nav2 33 |
|
||||
nav2b 34 |
|
OneToMany | |||
fruit fly (Drosophila melanogaster) |
Insecta | sick 34 |
|
OneToMany | |
worm (Caenorhabditis elegans) |
Secernentea | unc-53 34 |
|
OneToMany | |
sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for NAV2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for NAV2 Gene
(3) SIMAP similar genes for NAV2 Gene using alignment to 5 proteins:
Variants for NAV2 Gene
SNP ID | Clin | Chr 11 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs144875196 | uncertain-significance, Hirschsprung disease 1 | 19,948,935(+) | C/A/T | coding_sequence_variant, genic_upstream_transcript_variant, missense_variant, synonymous_variant | |
rs1000004774 | -- | 19,963,417(+) | C/T | genic_upstream_transcript_variant, intron_variant | |
rs1000005922 | -- | 19,428,723(+) | T/C | genic_upstream_transcript_variant, intron_variant | |
rs1000006959 | -- | 19,938,934(+) | A/C | genic_upstream_transcript_variant, intron_variant | |
rs1000012375 | -- | 19,816,853(+) | C/T | genic_upstream_transcript_variant, intron_variant |
Additional Variant Information for NAV2 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NAV2 Gene
Disorders for NAV2 Gene
Disorder | Aliases | PubMed IDs |
---|---|---|
neuroblastoma |
|
|
Additional Disease Information for NAV2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for NAV2 Gene
Publications for NAV2 Gene
- Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms. (PMID: 12062803) Coy JF … Poustka A (Gene 2002) 2 3 4 58
- Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans. (PMID: 12079279) Maes T … Buesa C (Genomics 2002) 2 3 4 58
- A mammalian homolog of unc-53 is regulated by all-trans retinoic acid in neuroblastoma cells and embryos. (PMID: 11904404) Merrill RA … Clagett-Dame M (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 4 22 58
- Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure. (PMID: 22174851) Lingappa JR … Partners in Prevention HSV/HIV Transmission Study Team (PloS one 2011) 3 44 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
Products for NAV2 Gene
- Browse R&D Systems for Antibodies
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- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for NAV2
- Origene Custom Protein Services for NAV2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NAV2
- Browse OriGene Inhibitory RNA Products For NAV2
- OriGene qPCR primer pairs for NAV2
- OriGene CRISPR knockouts for NAV2
- OriGene ORF clones in human for NAV2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For NAV2
- GenScript: Next-day shipping of latest version cDNA ORF clones for NAV2 in any vector
- XM_011520449.1
- NM_001111018.1
- XM_011520446.1
- XM_011520445.1
- XM_011520454.1
- XM_005253214.3
- XM_011520452.1
- XM_011520450.1
- NM_182964.5
- XM_011520447.1
- XM_006718364.2
- NM_001244963.1
- XM_006718369.1
- XM_006718367.2
- XM_006718366.2
- NM_145117.4
- XM_011520448.1
- NM_001111019.2
- XM_006718365.2
- XM_011520444.1
- XM_011520453.1
- XM_006718368.2
- XM_011520451.1
- GenScript Custom Purified and Recombinant Proteins Services for NAV2
- GenScript Custom Assay Services for NAV2
- GenScript Custom overexpressing Cell Line Services for NAV2
- GenScript: Design CRISPR guide RNA sequences for NAV2
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for NAV2
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
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- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for NAV2
- Novus Biologicals proteins and lysates for NAV2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam proteins for NAV2
- Find your target
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- Browse Antibodies at Cloud-Clone Corp.
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- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for NAV2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for NAV2
- VectorBuilder custom plasmid, inducible vectors for NAV2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NAV2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 31 available NAV2 Antibodies ranked by validation data
- Compare Top NAV2 Antibodies
- antibodies-online: Search results for available NAV2 related products ranked by validation data
- antibodies-online: Search results for 2 available NAV2 Proteins ranked by validation data
- Compare Top NAV2 Proteins
- GeneTex NAV2 antibody for NAV2
- Search GeneTex for Proteins for NAV2
- ViGene Biosciences adenoviral particle packaged cDNA for NAV2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for NAV2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for NAV2 gene
- Search ViGene Biosciences for NAV2
- Browse Santa Cruz Biotechnology (SCBT) Antibodies
- Search Santa Cruz Biotechnology (SCBT) for NAV2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for NAV2
- Horizon Cell Lines for NAV2
- genomics-online: cdna clones - Search results for 91 available NAV2 gene related products
- Overview of 91 available NAV2 gene related products
- orf clones - Search results for 91 available NAV2 gene related products
- Overview of 91 available NAV2 gene related products
- genomics-online: gRNA clones - Search results for 91 available NAV2 gene related products
- Overview of 91 available NAV2 gene related products
- genomics-online: primer clones - Search results for 91 available NAV2 gene related products
- Overview of 91 available NAV2 gene related products
- genomics-online: shRNA clones - Search results for 91 available NAV2 gene related products
- Overview of 91 available NAV2 gene related products
Sources for NAV2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
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- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew