External Ids for CCNB1 Gene
Previous HGNC Symbols for CCNB1 Gene
Previous GeneCards Identifiers for CCNB1 Gene
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008]
GeneCards Summary for CCNB1 Gene
CCNB1 (Cyclin B1) is a Protein Coding gene. Diseases associated with CCNB1 include Adrenal Carcinoma and Cervical Cancer, Somatic. Among its related pathways are Cell Cycle Checkpoints and FOXM1 transcription factor network. GO annotations related to this gene include protein kinase binding and patched binding. An important paralog of this gene is CCND2.
UniProtKB/Swiss-Prot for CCNB1 Gene
Essential for the control of the cell cycle at the G2/M (mitosis) transition.