Aliases for ADAM23 Gene
Aliases for ADAM23 Gene
External Ids for ADAM23 Gene
- HGNC: 202
- Entrez Gene: 8745
- Ensembl: ENSG00000114948
- OMIM: 603710
- UniProtKB: O75077
Previous GeneCards Identifiers for ADAM23 Gene
- GC02P205525
- GC02P206032
- GC02P207272
- GC02P207510
- GC02P207133
- GC02P207018
- GC02P199158
Summaries for ADAM23 Gene
-
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. It is reported that inactivation of this gene is associated with tumorigenesis in human cancers. [provided by RefSeq, May 2013]
GeneCards Summary for ADAM23 Gene
ADAM23 (ADAM Metallopeptidase Domain 23) is a Protein Coding gene. Among its related pathways are LGI-ADAM interactions and Developmental Biology. GO annotations related to this gene include metalloendopeptidase activity and metallopeptidase activity. An important paralog of this gene is ADAM11.
UniProtKB/Swiss-Prot for ADAM23 Gene
-
May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADAM23 Gene
Genomics for ADAM23 Gene
Regulatory Elements for ADAM23 Gene
Enhancers for ADAM23 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH02G206368 | 1 | Ensembl ENCODE | 10.6 | -74.9 | -74904 | 1.2 | MTA2 FEZF1 DPF2 ATF2 ZIC2 FOSL1 ARID1B TCF12 ZNF316 GATA2 | ADAM23 GPR1 GC02P206391 GC02P206342 |
| GH02G205729 | 1.6 | FANTOM5 Ensembl ENCODE dbSUPER | 4.5 | -710.9 | -710934 | 5.6 | PKNOX1 FOXA2 SIN3A BACH1 ZNF316 FOS NFE2 MAFK NFE2L2 EZH2 | ENSG00000225216 NRP2 ADAM23 GC02P205736 |
| GH02G206389 | 0.6 | ENCODE | 11.5 | -53.4 | -53422 | 1.4 | BHLHE40 JUNB FOSL1 ZNF766 JUND EED HMBOX1 FOS NFE2L2 | ADAM23 GPR1 NDUFS1 GC02P206391 GC02P206342 |
| GH02G206246 | 0.6 | Ensembl | 10.1 | -197.2 | -197239 | 0.2 | MTA2 BHLHE40 NBN RELB DPF2 TBX21 | GPR1 RN7SKP200 ZDBF2 SNORA41 EEF1B2 ADAM23 LOC100132849 HMGN1P6 |
| GH02G206443 | 0.7 | ENCODE | 0.7 | -0.1 | -88 | 0.3 | MXI1 RBBP5 GLIS2 EGR1 POLR2A SCRT2 PATZ1 ZNF600 EZH2 MAZ | ADAM23 HNRNPA1P51 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ADAM23 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for ADAM23 Gene
- Chromosome:
- 2
- Start:
- 206,443,539 bp from pter
- End:
- 206,621,130 bp from pter
- Size:
- 177,592 bases
- Orientation:
- Plus strand
Genomic View for ADAM23 Gene
Genes around ADAM23 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q33.3 by Ensembl
- 2q33.3 by Entrez Gene
- 2q33.3 by HGNC
ADAM23 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ADAM23 Gene
Proteins for ADAM23 Gene
-
Protein details for ADAM23 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O75077-ADA23_HUMAN
- Recommended name:
- Disintegrin and metalloproteinase domain-containing protein 23
- Protein Accession:
- O75077
- A2RU59
Protein attributes for ADAM23 Gene
- Size:
- 832 amino acids
- Molecular mass:
- 91926 Da
- Quaternary structure:
-
- Can bind to LGI1 and LGI4 (By similarity). Ligand for integrin alpha-V/beta-3.
Protein Expression for ADAM23 Gene
Post-translational modifications for ADAM23 Gene
Other Protein References for ADAM23 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for ADAM23 (ADAM23)
-
Custom Antibody ServicesOriGene Antibodies for ADAM23
- Novus Biologicals Antibodies for ADAM23
- Invitrogen Antibodies for ADAM23
- antibodies-online Antibodies for ADAM23: See all 66
- GeneTex ADAM23 antibody for ADAM23
Protein Products
- R&D Systems Proteins and Enzymes for ADAM23
-
OriGene Purified Proteins for ADAM23
- Search Origene for MassSpec and Protein Over-expression Lysates for ADAM23
- Origene Custom Protein Services for ADAM23
- Search GeneTex for Proteins for ADAM23
Assay Products
- antibodies-online Kits for ADAM23: See all 2
No data available for DME Specific Peptides for ADAM23 Gene
Domains & Families for ADAM23 Gene
Gene Families for ADAM23 Gene
- HGNC:
- IUPHAR :
Protein Domains for ADAM23 Gene
Suggested Antigen Peptide Sequences for ADAM23 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O75077UniProtKB/Swiss-Prot:
ADA23_HUMAN :- A conserved motif AVN[ED]CD within the disintegrin-like domain could be involved in the binding to the integrin receptor.
- Domain:
-
- A conserved motif AVN[ED]CD within the disintegrin-like domain could be involved in the binding to the integrin receptor.
Function for ADAM23 Gene
Molecular function for ADAM23 Gene
- GENATLAS Biochemistry:
- a disintegrin and metalloprotease domain 23,membrane anchored cell surface adhesion protein,expressed in the brain
- UniProtKB/Swiss-Prot Function:
- May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004222 | metalloendopeptidase activity | IEA | -- |
| GO:0005178 | integrin binding | TAS | 9693107 |
| GO:0005515 | protein binding | IPI | 20463223 |
| GO:0008237 | metallopeptidase activity | IEA,TAS | 9693107 |
Phenotypes for ADAM23 Gene
- MGI mutant phenotypes for ADAM23:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for ADAM23:
Animal Model Products
-
Taconic Biosciences Mouse Models for ADAM23
- Cyagen custom Knockout/knockin (KOKI) mouse models for ADAM23
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ADAM23 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ADAM23 gene
- Search ViGene Biosciences for ADAM23
CRISPR Products
-
OriGene CRISPR knockouts for ADAM23
-
Applied Biological Materials CRISPR for ADAM23
-
Santa Cruz Biotechnology (SCBT) CRISPR for ADAM23
- GenScript: Design CRISPR guide RNA sequences for ADAM23
miRNA for ADAM23 Gene
- miRTarBase miRNAs that target ADAM23
miRNA Products
- Search ViGene Biosciences for ADAM23
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ADAM23
- Browse OriGene Inhibitory RNA Products For ADAM23
-
ViGene Biosciences ready-to-package AAV shRNAs for ADAM23 gene
Clone Products
-
OriGene ORF clones in human for ADAM23
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ADAM23
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ADAM23
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ADAM23
-
ViGene Biosciences adenoviral particle packaged cDNA for ADAM23 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ADAM23 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ADAM23 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ADAM23 Gene
Localization for ADAM23 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ADAM23 Gene
- Cell membrane; Single-pass type I membrane protein.
- Isoform Gamma: Secreted.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 5 |
| cytoskeleton | 2 |
| cytosol | 2 |
| endoplasmic reticulum | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0005887 | integral component of plasma membrane | TAS | 9693107 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for ADAM23 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Developmental Biology | ||
| 2 | LGI-ADAM interactions | ||
Pathways by source for ADAM23 Gene
2 Reactome pathways for ADAM23 Gene
Interacting Proteins for ADAM23 Gene
Selected Interacting proteins:
O75077-ADA23_HUMAN
ENSP00000264377
for ADAM23 Gene via
IID
MINT
STRING
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006508 | proteolysis | IEA | -- |
| GO:0007155 | cell adhesion | IEA | -- |
| GO:0007417 | central nervous system development | TAS | 9693107 |
No data available for SIGNOR curated interactions for ADAM23 Gene
Transcripts for ADAM23 Gene
mRNA/cDNA for ADAM23 Gene
- (3) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (62) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ADAM23 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ADAM23
-
Applied Biological Materials CRISPR for ADAM23
-
Santa Cruz Biotechnology (SCBT) CRISPR for ADAM23
- GenScript: Design CRISPR guide RNA sequences for ADAM23
miRNA Products
- Search ViGene Biosciences for ADAM23
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ADAM23
- Browse OriGene Inhibitory RNA Products For ADAM23
-
ViGene Biosciences ready-to-package AAV shRNAs for ADAM23 gene
Clone Products
-
OriGene ORF clones in human for ADAM23
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ADAM23
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ADAM23
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for ADAM23 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Mesenchymal Stem Cells (Uncategorized)
-
Blood (Hematopoietic System)
- Small Pre B-Cells Hematopoietic Bone Marrow
- T Helper Cells Thymus
- Umbilical Cord (Extraembryonic Tissues)
-
Thymus (Hematopoietic System)
- T Helper Cells Thymus
-
Head Mesenchyme (Muscoskeletal System)
- Dental Mesenchymal Cells Branchial Arch 1
-
Tooth
- Dental Mesenchymal Cells Branchial Arch 1
- Ovary (Reproductive System)
- Eye (Sensory Organs)
-
Testis (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for ADAM23 Gene
This gene is overexpressed in Brain - Frontal Cortex (BA9) (x5.6), Brain - Nucleus accumbens (basal ganglia) (x4.5), Heart - Left Ventricle (x4.4), and Brain - Anterior cingulate cortex (BA24) (x4.1).
This gene is overexpressed in Frontal cortex (50.8), Brain (8.8), and Spinal cord (8.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ADAM23 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ADAM23 Gene:
ADAM23SOURCE GeneReport for Unigene cluster for ADAM23 Gene:
Hs.591643mRNA Expression by UniProt/SwissProt for ADAM23 Gene:
O75077-ADA23_HUMAN
Tissue specificity:
Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole.
Evidence on tissue expression from TISSUES for ADAM23 Gene
- Nervous system(4.6)
Primer Products
-
OriGene qPCR primer pairs for ADAM23
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for ADAM23 Gene
Orthologs for ADAM23 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ADAM23 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | ADAM23 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | ADAM23 34 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | ADAM23 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Adam23 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Adam23 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ADAM23 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ADAM23 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | ADAM23 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | adam23 34 |
|
||
| Str.12051 34 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | ADAM23 (2 of 2) 35 |
|
OneToMany | |
| wu:fj40f01 34 |
|
||||
| adam23a 35 |
|
OneToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | mmd 36 35 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | adm-1 36 |
|
|
|
| unc-71 35 |
|
OneToMany |
- Species where no ortholog for ADAM23 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ADAM23 Gene
(14) SIMAP similar genes for ADAM23 Gene using alignment to 7 proteins:
Variants for ADAM23 Gene
| SNP ID | Clin | Chr 02 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000002980 | -- | 206,483,157(+) | TCAAT(A/G)AATCT | intron-variant | |
| rs1000006541 | -- | 206,500,604(+) | ATCTC(C/T)TCTCC | intron-variant | |
| rs1000029130 | -- | 206,615,308(+) | TACAG(G/T)TTATG | intron-variant | |
| rs1000032401 | -- | 206,613,839(+) | GCTAT(G/T)TATCT | intron-variant | |
| rs1000033702 | -- | 206,604,582(+) | AGAAA(C/T)CAGGT | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3344531 | CNV | insertion | 20981092 |
| esv3594069 | CNV | loss | 21293372 |
| nsv1011347 | CNV | gain | 25217958 |
| nsv1072485 | CNV | deletion | 25765185 |
| nsv1116823 | CNV | deletion | 24896259 |
| nsv1126576 | CNV | deletion | 24896259 |
| nsv1153377 | CNV | insertion | 26484159 |
| nsv472414 | CNV | novel sequence insertion | 20440878 |
| nsv477754 | CNV | novel sequence insertion | 20440878 |
| nsv478360 | CNV | novel sequence insertion | 20440878 |
| nsv584247 | CNV | gain | 21841781 |
| nsv954823 | CNV | duplication | 24416366 |
| nsv954824 | CNV | duplication | 24416366 |
Residual Variation Intolerance Score:
9.87% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.61;
31.03% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ADAM23 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ADAM23
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ADAM23 Gene
Disorders for ADAM23 Gene
Relevant External Links for ADAM23
No disorders were found for ADAM23 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ADAM23 Gene
Publications for ADAM23 Gene
- Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3: novel human cellular disintegrins highly expressed in the brain. (PMID: 9693107) Sagane K. … Tanaka I. (Biochem. J. 1998) 2 3 4 22 64
- Two novel isoforms of Adam23 expressed in the developmental process of mouse and human brains. (PMID: 14697522) Sun Y.P. … Zhao S. (Gene 2004) 3 4 22 64
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- Association and interaction analyses of eight genes under asthma linkage peaks. (PMID: 19824886) Ferreira M.A. … Duffy D.L. (Allergy 2009) 3 46 64
- ADAM 23/MDC3, a human disintegrin that promotes cell adhesion via interaction with the alpha v beta 3 integrin through an RGD- independent mechanism. (PMID: 10749942) Cal S. … Lopez-Otin C. (Mol. Biol. Cell 2000) 3 4 64
Products for ADAM23 Gene
- R&D Systems Antibodies for ADAM23 (ADAM23)
- R&D Systems Proteins and Enzymes for ADAM23
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- Custom Antibody ServicesOriGene Antibodies for ADAM23
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- OriGene qPCR primer pairs for ADAM23
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- Novus Biologicals Antibodies for ADAM23
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- Cloud-Clone Corp. disease models service
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- Taconic Biosciences Mouse Models for ADAM23
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for ADAM23
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- antibodies-online Antibodies for ADAM23: See all 66
- antibodies-online Kits for ADAM23: See all 2
- Search antibodies-online for proteins
- Search antibodies-online for peptides
- GeneTex ADAM23 antibody for ADAM23
- Search GeneTex for Proteins for ADAM23
- ViGene Biosciences adenoviral particle packaged cDNA for ADAM23 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ADAM23 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ADAM23 gene
- Search ViGene Biosciences for ADAM23
- Horizon Cell Lines for ADAM23
- Cyagen custom Knockout/knockin (KOKI) mouse models for ADAM23
- VectorBuilder custom plasmid, inducible vectors for ADAM23
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ADAM23
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ADAM23 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus Biologicals
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
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