External Ids for SNX4 Gene
Previous GeneCards Identifiers for SNX4 Gene
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2012]
GeneCards Summary for SNX4 Gene
SNX4 (Sorting Nexin 4) is a Protein Coding gene. Among its related pathways are TGF-beta Receptor Signaling Pathway and Endocytosis. GO annotations related to this gene include phosphatidylinositol binding and epidermal growth factor receptor binding. An important paralog of this gene is SNX7.
UniProtKB/Swiss-Prot for SNX4 Gene
May be involved in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation.