Aliases for NPFF Gene
External Ids for NPFF Gene
Previous GeneCards Identifiers for NPFF Gene
FMFRamide-related protein precursor plays a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. FMRFAL encodes a preproprotein which is cleaved to form two active peptides with similar function. [provided by RefSeq, Jul 2008]
GeneCards Summary for NPFF Gene
NPFF (Neuropeptide FF-Amide Peptide Precursor) is a Protein Coding gene. Diseases associated with NPFF include opioid abuse and opiate dependence. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include receptor binding and neuropeptide hormone activity.
UniProtKB/Swiss-Prot for NPFF Gene
Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels.