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Aliases for FAM188B Gene

Aliases for FAM188B Gene

  • Family With Sequence Similarity 188, Member B 2 3
  • C7orf67 3 4
  • Chromosome 7 Open Reading Frame 67 2
  • Protein FAM188B 3

External Ids for FAM188B Gene

Previous HGNC Symbols for FAM188B Gene

  • C7orf67

Previous GeneCards Identifiers for FAM188B Gene

  • GC07P030779
  • GC07P030812

Summaries for FAM188B Gene

GeneCards Summary for FAM188B Gene

FAM188B (Family With Sequence Similarity 188, Member B) is a Protein Coding gene. An important paralog of this gene is FAM188A.

Gene Wiki entry for FAM188B Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM188B Gene

Genomics for FAM188B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM188B Gene

30,771,417 bp from pter
30,892,387 bp from pter
120,971 bases
Plus strand

Genomic View for FAM188B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM188B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM188B Gene

No data available for Regulatory Elements for FAM188B Gene

Proteins for FAM188B Gene

  • Protein details for FAM188B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM188B
    Protein Accession:
    Secondary Accessions:
    • Q71AZ7
    • Q9H6D2

    Protein attributes for FAM188B Gene

    757 amino acids
    Molecular mass:
    84372 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAQ10898.1; Type=Frameshift; Positions=617; Evidence={ECO:0000305}; Sequence=BAB15327.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};

neXtProt entry for FAM188B Gene

Proteomics data for FAM188B Gene at MOPED

Post-translational modifications for FAM188B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM188B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM188B Gene

Domains for FAM188B Gene

Protein Domains for FAM188B Gene


Suggested Antigen Peptide Sequences for FAM188B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM188 family.
  • Belongs to the FAM188 family.
genes like me logo Genes that share domains with FAM188B: view

No data available for Gene Families for FAM188B Gene

Function for FAM188B Gene

Animal Model Products

CRISPR Products

miRNA for FAM188B Gene

miRTarBase miRNAs that target FAM188B

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM188B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM188B Gene

Localization for FAM188B Gene

Subcellular locations from

Jensen Localization Image for FAM188B Gene COMPARTMENTS Subcellular localization image for FAM188B gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM188B Gene

Pathways for FAM188B Gene

SuperPathways for FAM188B Gene

No Data Available

Interacting Proteins for FAM188B Gene

Selected Interacting proteins: Q4G0A6-F188B_HUMAN for FAM188B Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for FAM188B Gene


No data available for Pathways by source for FAM188B Gene

Transcripts for FAM188B Gene

mRNA/cDNA for FAM188B Gene

Unigene Clusters for FAM188B Gene

Family with sequence similarity 188, member B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM188B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM188B Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c · 8d ^ 9
SP1: -
SP3: - - -
SP4: - - -
SP5: - -
SP6: -

Relevant External Links for FAM188B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM188B Gene

mRNA expression in normal human tissues for FAM188B Gene

Protein differential expression in normal tissues for FAM188B Gene

This gene is overexpressed in Serum (48.6) and Platelet (15.9).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for FAM188B Gene

SOURCE GeneReport for Unigene cluster for FAM188B Gene Hs.660192

genes like me logo Genes that share expressions with FAM188B: view

Expression partners for FAM188B Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM188B Gene

Orthologs for FAM188B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM188B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM188B 35
  • 82.32 (n)
  • 78.51 (a)
FAM188B 36
  • 78 (a)
(Canis familiaris)
Mammalia FAM188B 35
  • 85.28 (n)
  • 82.1 (a)
FAM188B 36
  • 81 (a)
(Mus musculus)
Mammalia Fam188b 35
  • 80.8 (n)
  • 76.29 (a)
Fam188b 16
Fam188b 36
  • 75 (a)
(Pan troglodytes)
Mammalia FAM188B 35
  • 99.43 (n)
  • 98.68 (a)
FAM188B 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Fam188b 35
  • 79.78 (n)
  • 75.33 (a)
(Monodelphis domestica)
Mammalia FAM188B 36
  • 49 (a)
(Ornithorhynchus anatinus)
Mammalia FAM188B 36
  • 65 (a)
(Gallus gallus)
Aves FAM188B 35
  • 61.72 (n)
  • 57.01 (a)
FAM188B 36
  • 51 (a)
(Anolis carolinensis)
Reptilia FAM188B 36
  • 47 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam188b 35
  • 57.93 (n)
  • 51.03 (a)
Str.11231 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.14505 35
(Danio rerio)
Actinopterygii si:dkey-30h22.11 35
  • 55.59 (n)
  • 53.56 (a)
FAM188B 36
  • 43 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.13006 35
Species with no ortholog for FAM188B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM188B Gene

Gene Tree for FAM188B (if available)
Gene Tree for FAM188B (if available)

Paralogs for FAM188B Gene

Paralogs for FAM188B Gene

genes like me logo Genes that share paralogs with FAM188B: view

Variants for FAM188B Gene

Sequence variations from dbSNP and Humsavar for FAM188B Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
VAR_062248 -
VAR_039217 -
VAR_039216 -
VAR_039215 -
VAR_039214 -

Structural Variations from Database of Genomic Variants (DGV) for FAM188B Gene

Variant ID Type Subtype PubMed ID
nsv436557 CNV Deletion 17901297
nsv527038 CNV Gain 19592680
nsv830938 CNV Gain 17160897
nsv830939 CNV Loss 17160897
nsv464416 CNV Loss 19166990
esv269741 CNV Insertion 20981092
nsv526591 CNV Loss 19592680
esv2734203 CNV Deletion 23290073
esv22626 CNV Gain 19812545
esv2678492 CNV Deletion 23128226
esv2390406 CNV Deletion 18987734
esv5109 CNV Deletion 18987735
esv2678752 CNV Deletion 23128226
esv2734204 CNV Deletion 23290073
esv5499 CNV Loss 19470904
esv993279 CNV Deletion 20482838

Relevant External Links for FAM188B Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM188B Gene

Disorders for FAM188B Gene

(1) University of Copenhagen DISEASES for FAM188B Gene

Relevant External Links for FAM188B

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with FAM188B: view

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships and Genatlas for FAM188B Gene

Publications for FAM188B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 48
  3. A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1. (PMID: 22396660) Urabe Y. … Matsuda K. (PLoS Genet. 2012) 3 48
  4. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for FAM188B Gene

Sources for FAM188B Gene

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