External Ids for STX7 Gene
Previous GeneCards Identifiers for STX7 Gene
The protein encoded by this gene is a syntaxin family membrane receptor involved in vesicle transport. The encoded protein binds alpha-SNAP, an important regulator of transport vesicle fusion. Along with syntaxin 13, this protein plays a role in the ordered fusion of endosomes and lysosomes with the phagosome. [provided by RefSeq, May 2016]
GeneCards Summary for STX7 Gene
STX7 (Syntaxin 7) is a Protein Coding gene. Diseases associated with STX7 include Leukodystrophy, Hypomyelinating, 6 and Hemophagocytic Lymphohistiocytosis, Familial, 4. Among its related pathways are Delta508-CFTR traffic / ER-to-Golgi in CF and Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics. GO annotations related to this gene include syntaxin binding and SNAP receptor activity. An important paralog of this gene is STX12.
UniProtKB/Swiss-Prot for STX7 Gene
May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes.