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Aliases for SLC10A7 Gene

Aliases for SLC10A7 Gene

  • Solute Carrier Family 10 Member 7 2 3 4 5
  • Solute Carrier Family 10, Member 7 2 3
  • Na(+)/Bile Acid Cotransporter 7 3 4
  • C4orf13 3 4
  • P7 3 4
  • Solute Carrier Family 10 (Sodium/Bile Acid Cotransporter Family), Member 7 3
  • Chromosome 4 Open Reading Frame 13 2
  • SBF-Domain Containing Protein 3

External Ids for SLC10A7 Gene

Previous HGNC Symbols for SLC10A7 Gene

  • C4orf13

Previous GeneCards Identifiers for SLC10A7 Gene

  • GC04M147396
  • GC04M147175
  • GC04M142895

Summaries for SLC10A7 Gene

GeneCards Summary for SLC10A7 Gene

SLC10A7 (Solute Carrier Family 10 Member 7) is a Protein Coding gene. GO annotations related to this gene include symporter activity.

Gene Wiki entry for SLC10A7 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC10A7 Gene

Genomics for SLC10A7 Gene

Regulatory Elements for SLC10A7 Gene

Enhancers for SLC10A7 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SLC10A7 on UCSC Golden Path with GeneCards custom track

Promoters for SLC10A7 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SLC10A7 on UCSC Golden Path with GeneCards custom track

Genomic Location for SLC10A7 Gene

146,253,975 bp from pter
146,521,971 bp from pter
267,997 bases
Minus strand

Genomic View for SLC10A7 Gene

Genes around SLC10A7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC10A7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC10A7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC10A7 Gene

Proteins for SLC10A7 Gene

  • Protein details for SLC10A7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Sodium/bile acid cotransporter 7
    Protein Accession:
    Secondary Accessions:
    • A7E2E6
    • A7MAX9
    • Q0VAP9
    • Q45NG1
    • Q45NG2
    • Q5H9S6
    • Q6P4E6
    • Q8IZ62
    • Q8NBP8
    • Q9H0M9

    Protein attributes for SLC10A7 Gene

    358 amino acids
    Molecular mass:
    39485 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC11571.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for SLC10A7 Gene

neXtProt entry for SLC10A7 Gene

Proteomics data for SLC10A7 Gene at MOPED

Post-translational modifications for SLC10A7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for SLC10A7 Gene

Domains & Families for SLC10A7 Gene

Gene Families for SLC10A7 Gene

Protein Domains for SLC10A7 Gene

Suggested Antigen Peptide Sequences for SLC10A7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the unknown BART superfamily-1 (UBS1) (TC 2.A.93) family.
  • Belongs to the unknown BART superfamily-1 (UBS1) (TC 2.A.93) family.
genes like me logo Genes that share domains with SLC10A7: view

Function for SLC10A7 Gene

genes like me logo Genes that share phenotypes with SLC10A7: view

Animal Model Products

  • Taconic Biosciences Mouse Models for SLC10A7

CRISPR Products

miRNA for SLC10A7 Gene

miRTarBase miRNAs that target SLC10A7

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SLC10A7 Gene

Localization for SLC10A7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC10A7 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SLC10A7 Gene COMPARTMENTS Subcellular localization image for SLC10A7 gene
Compartment Confidence
plasma membrane 4
nucleus 3

No data available for Gene Ontology (GO) - Cellular Components for SLC10A7 Gene

Pathways & Interactions for SLC10A7 Gene

SuperPathways for SLC10A7 Gene

No Data Available

Interacting Proteins for SLC10A7 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000334594 Q0GE19-NTCP7_HUMAN for SLC10A7 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for SLC10A7 Gene


No data available for Pathways by source and SIGNOR curated interactions for SLC10A7 Gene

Drugs & Compounds for SLC10A7 Gene

(1) Additional Compounds for SLC10A7 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
  • Sodium
  • Sodium ion
genes like me logo Genes that share compounds with SLC10A7: view

Transcripts for SLC10A7 Gene

Unigene Clusters for SLC10A7 Gene

Solute carrier family 10 (sodium/bile acid cotransporter family), member 7:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLC10A7 Gene

No ASD Table

Relevant External Links for SLC10A7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC10A7 Gene

mRNA expression in normal human tissues for SLC10A7 Gene

Protein differential expression in normal tissues from HIPED for SLC10A7 Gene

This gene is overexpressed in Placenta (62.5) and Islet of Langerhans (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for SLC10A7 Gene

SOURCE GeneReport for Unigene cluster for SLC10A7 Gene Hs.659209

genes like me logo Genes that share expression patterns with SLC10A7: view

Protein tissue co-expression partners for SLC10A7 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SLC10A7 Gene

Orthologs for SLC10A7 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for SLC10A7 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SLC10A7 35
  • 94.48 (n)
  • 95.17 (a)
-- 36
  • 90 (a)
SLC10A7 36
  • 91 (a)
(Canis familiaris)
Mammalia SLC10A7 35
  • 94.02 (n)
  • 97.06 (a)
SLC10A7 36
  • 97 (a)
(Mus musculus)
Mammalia Slc10a7 35
  • 87.35 (n)
  • 94.71 (a)
Slc10a7 16
Slc10a7 36
  • 95 (a)
(Pan troglodytes)
Mammalia LOC740545 35
  • 100 (n)
  • 100 (a)
SLC10A7 36
  • 92 (a)
(Rattus norvegicus)
Mammalia Slc10a7 35
  • 86.86 (n)
  • 94.41 (a)
(Monodelphis domestica)
Mammalia SLC10A7 36
  • 79 (a)
(Ornithorhynchus anatinus)
Mammalia SLC10A7 36
  • 93 (a)
(Gallus gallus)
Aves SLC10A7 35
  • 82.87 (n)
  • 88.31 (a)
SLC10A7 36
  • 87 (a)
(Anolis carolinensis)
Reptilia SLC10A7 36
  • 87 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia slc10a7 35
  • 79.43 (n)
  • 87.54 (a)
Str.16755 35
African clawed frog
(Xenopus laevis)
Amphibia dkfzp566m114-prov 35
(Danio rerio)
Actinopterygii slc10a7 35
  • 70.49 (n)
  • 76.74 (a)
slc10a7 36
  • 75 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ABR085C 35
  • 44.51 (n)
  • 28.88 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 20 (a)
RCH1 38
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.8480 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6964 36
  • 55 (a)
Species with no ortholog for SLC10A7:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SLC10A7 Gene

Gene Tree for SLC10A7 (if available)
Gene Tree for SLC10A7 (if available)

Paralogs for SLC10A7 Gene

No data available for Paralogs for SLC10A7 Gene

Variants for SLC10A7 Gene

Sequence variations from dbSNP and Humsavar for SLC10A7 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1001192 -- 146,257,824(+) atcct(C/T)tgaac intron-variant
rs1148128 -- 146,274,118(-) TTTAA(A/G)ATCAT intron-variant
rs1174761 -- 146,274,061(-) ATTCA(A/G)AATGC intron-variant
rs1385845 -- 146,326,139(+) GAGTC(C/T)CAATC intron-variant
rs1385846 -- 146,326,460(+) ACTGG(G/T)CTCCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC10A7 Gene

Variant ID Type Subtype PubMed ID
nsv461675 CNV Gain 19166990
nsv822765 CNV Gain 20364138
nsv822766 CNV Loss 20364138
esv27195 CNV Loss 19812545
esv2728494 CNV Deletion 23290073
nsv4537 CNV Insertion 18451855
esv8434 CNV Loss 19470904
esv2728495 CNV Deletion 23290073
esv1004247 CNV Deletion 20482838
esv2438325 CNV Insertion 19546169
nsv819040 CNV Loss 19587683
nsv509017 CNV Insertion 20534489
esv1000928 CNV Insertion 20482838
esv267902 CNV Insertion 20981092
esv273732 CNV Insertion 20981092
esv1640176 CNV Insertion 17803354
esv2661274 CNV Deletion 23128226
nsv822767 CNV Loss 20364138
esv2662568 CNV Deletion 23128226
esv28273 CNV Gain 19812545
nsv428453 CNV Gain 18775914
esv2550267 CNV Insertion 19546169
esv269966 CNV Insertion 20981092
esv271331 CNV Insertion 20981092
nsv4538 CNV Insertion 18451855

Variation tolerance for SLC10A7 Gene

Residual Variation Intolerance Score: 50.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.51; 29.37% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for SLC10A7 Gene

Disorders for SLC10A7 Gene

Relevant External Links for SLC10A7

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SLC10A7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SLC10A7 Gene

Publications for SLC10A7 Gene

  1. Molecular cloning and characterization of a novel human C4orf13 gene, tentatively a member of the sodium bile acid cotransporter family. (PMID: 15932064) Zou X. … Mao Y. (Biochem. Genet. 2005) 2 3 4 23 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality. (PMID: 24159190) SeppAolAo I. … LehtimAoki T. (Eur. Heart J. 2014) 3
  4. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. (PMID: 23583979) den Hoed M. … Loos R.J. (Nat. Genet. 2013) 3
  5. Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PMID: 19240061) Trynka G. … Wijmenga C. (Gut 2009) 3

Products for SLC10A7 Gene

Sources for SLC10A7 Gene