Aliases for SLC25A31 Gene
External Ids for SLC25A31 Gene
Previous GeneCards Identifiers for SLC25A31 Gene
The protein encoded by this gene is a member of the ADP/ATP carrier family of proteins that exchange cytosolic ADP for matrix ATP in the mitochondria. Cells over-expressing this gene have been shown to display an anti-apoptotic phenotype. This protein is also thought to play a role in spermatogenesis, where it is believed to associate with a part of the flagellar cytoskeleton and with glycolytic enzymes. Male mice with mutations in the mouse ortholog of this gene are sterile and spermatocytes display an early meiotic arrest phenotype. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
GeneCards Summary for SLC25A31 Gene
SLC25A31 (Solute Carrier Family 25 Member 31) is a Protein Coding gene. Among its related pathways are Necroptosis and Calcium signaling pathway. Gene Ontology (GO) annotations related to this gene include transporter activity. An important paralog of this gene is SLC25A4.
UniProtKB/Swiss-Prot for SLC25A31 Gene
Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility.