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Aliases for SNN Gene

Aliases for SNN Gene

  • Stannin 2 3
  • AG8_1 3 4

External Ids for SNN Gene

Previous GeneCards Identifiers for SNN Gene

  • GC16P011545
  • GC16P011914
  • GC16P011728

Summaries for SNN Gene

GeneCards Summary for SNN Gene

SNN (Stannin) is a Protein Coding gene. Diseases associated with SNN include cavernous hemangioma.

UniProtKB/Swiss-Prot for SNN Gene

  • Plays a role in the toxic effects of organotins

Gene Wiki entry for SNN Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNN Gene

Genomics for SNN Gene

Regulatory Elements for SNN Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SNN Gene

11,668,414 bp from pter
11,679,159 bp from pter
10,746 bases
Plus strand

Genomic View for SNN Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNN Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNN Gene

Proteins for SNN Gene

  • Protein details for SNN Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein Accession:
    Secondary Accessions:
    • D3DUG4
    • Q6FGI0

    Protein attributes for SNN Gene

    88 amino acids
    Molecular mass:
    9497 Da
    Quaternary structure:
    • Monomer.

    Three dimensional structures from OCA and Proteopedia for SNN Gene

neXtProt entry for SNN Gene

Proteomics data for SNN Gene at MOPED

Post-translational modifications for SNN Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SNN Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SNN Gene

Domains for SNN Gene

Protein Domains for SNN Gene

Suggested Antigen Peptide Sequences for SNN Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • O75324
  • Belongs to the stannin family.
genes like me logo Genes that share domains with SNN: view

No data available for Gene Families for SNN Gene

Function for SNN Gene

Molecular function for SNN Gene

GENATLAS Biochemistry: stannin,involved in the toxic effect of organotins
UniProtKB/Swiss-Prot Function: Plays a role in the toxic effects of organotins

Phenotypes for SNN Gene

GenomeRNAi human phenotypes for SNN:
genes like me logo Genes that share phenotypes with SNN: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SNN

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SNN Gene

Localization for SNN Gene

Subcellular locations from UniProtKB/Swiss-Prot for SNN Gene

Mitochondrion outer membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SNN Gene COMPARTMENTS Subcellular localization image for SNN gene
Compartment Confidence
mitochondrion 5
extracellular 3
nucleus 2
cytosol 1

Gene Ontology (GO) - Cellular Components for SNN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005741 mitochondrial outer membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SNN: view

Pathways for SNN Gene

SuperPathways for SNN Gene

No Data Available

PCR Array Products

  • Pathway & Disease-focused RT² Profiler PCR Arrays

Interacting Proteins for SNN Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000329287 O75324-SNN_HUMAN for SNN Gene via STRING I2D

Gene Ontology (GO) - Biological Process for SNN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006950 response to stress TAS 9657854
GO:0009628 response to abiotic stimulus TAS 9657854
genes like me logo Genes that share ontologies with SNN: view

No data available for Pathways by source for SNN Gene

Compounds for SNN Gene

(3) Novoseek inferred chemical compound relationships for SNN Gene

Compound -log(P) Hits PubMed IDs
trimethyltin 94.1 21
dimethyltin 91.5 2
lipid 0 4
genes like me logo Genes that share compounds with SNN: view

Transcripts for SNN Gene

mRNA/cDNA for SNN Gene

(197) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(8) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SNN Gene

Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SNN

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNN Gene

No ASD Table

Relevant External Links for SNN Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNN Gene

mRNA expression in normal human tissues for SNN Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SNN Gene

SOURCE GeneReport for Unigene cluster for SNN Gene Hs.618526

genes like me logo Genes that share expressions with SNN: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SNN Gene

Orthologs for SNN Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNN Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SNN 35
  • 100 (n)
  • 100 (a)
SNN 36
  • 100 (a)
(Bos Taurus)
Mammalia SNN 35
  • 93.02 (n)
  • 100 (a)
SNN 36
  • 99 (a)
(Canis familiaris)
Mammalia SNN 35
  • 92.72 (n)
  • 100 (a)
SNN 36
  • 100 (a)
(Mus musculus)
Mammalia Snn 35
  • 89.02 (n)
  • 97.73 (a)
Snn 16
Snn 36
  • 98 (a)
(Monodelphis domestica)
Mammalia SNN 36
  • 100 (a)
(Ornithorhynchus anatinus)
Mammalia SNN 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Snn 35
  • 89.39 (n)
  • 97.73 (a)
(Gallus gallus)
Aves SNN 35
  • 81.01 (n)
  • 95.35 (a)
SNN 36
  • 94 (a)
(Anolis carolinensis)
Reptilia SNN 36
  • 78 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.8490 35
tropical clawed frog
(Silurana tropicalis)
Amphibia snn 35
  • 80.23 (n)
  • 90.7 (a)
(Danio rerio)
Actinopterygii snn 35
  • 79.46 (n)
  • 89.53 (a)
snn 36
  • 89 (a)
wufj47f06 35
Species with no ortholog for SNN:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNN Gene

Gene Tree for SNN (if available)
Gene Tree for SNN (if available)

Paralogs for SNN Gene

No data available for Paralogs for SNN Gene

Variants for SNN Gene

Sequence variations from dbSNP and Humsavar for SNN Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs1050048 -- 11,677,615(+) GGCTC(C/T)CTGGT utr-variant-3-prime
rs1050049 -- 11,677,850(+) AAAGG(C/T)ACCTC utr-variant-3-prime
rs1050068 -- 11,676,092(+) ACGGG(C/T)GTGGT reference, synonymous-codon
rs1050069 -- 11,676,107(+) GTCAT(C/T)GTCAT reference, synonymous-codon
rs1802408 -- 11,678,357(+) TCACC(A/G)CAGCC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for SNN Gene

Variant ID Type Subtype PubMed ID
nsv457409 CNV Gain 19166990
nsv524676 CNV Loss 19592680
esv22331 CNV Loss 19812545

Relevant External Links for SNN Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SNN Gene

Disorders for SNN Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for SNN Gene including...

Search for SNN Gene in MalaCards »

(1) University of Copenhagen DISEASES for SNN Gene

(3) Novoseek inferred disease relationships for SNN Gene

Disease -log(P) Hits PubMed IDs
intoxication 33.5 1
necrosis 11.7 3
tumors 0 3

Relevant External Links for SNN

Genetic Association Database (GAD)
genes like me logo Genes that share disorders with SNN: view

No data available for UniProtKB/Swiss-Prot for SNN Gene

Publications for SNN Gene

  1. Chromosomal localization and characterization of the stannin (Snn) gene. (PMID: 9657854) Dejneka N.S. … Billingsley M.L. (Mamm. Genome 1998) 2 3 4 23
  2. Vascular endothelial genes that are responsive to tumor necrosis factor-alpha in vitro are expressed in atherosclerotic lesions, including inhibitor of apoptosis protein-1, stannin, and two novel genes. (PMID: 10233894) Horrevoets A.J.G. … Pannekoek H. (Blood 1999) 3 4 23
  3. Molecular neurotoxicology of trimethyltin: identification of stannin, a novel protein expressed in trimethyltin-sensitive cells. (PMID: 1635553) Toggas S.M. … Billingsley M.L. (Mol. Pharmacol. 1992) 3 23
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Structure, dynamics, and membrane topology of stannin: a mediator of neuronal cell apoptosis induced by trimethyltin chloride. (PMID: 16246365) Buck-Koehntop B.A. … Veglia G. (J. Mol. Biol. 2005) 4 23

Products for SNN Gene

Sources for SNN Gene

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