Aliases for LAS1L Gene
External Ids for LAS1L Gene
Previous GeneCards Identifiers for LAS1L Gene
GeneCards Summary for LAS1L Gene
LAS1L (LAS1-Like (S. Cerevisiae)) is a Protein Coding gene. Diseases associated with LAS1L include spinal muscular atrophy with respiratory distress type 2.
UniProtKB/Swiss-Prot for LAS1L Gene
Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.