Aliases for AMN Gene
External Ids for AMN Gene
The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila. [provided by RefSeq, Jul 2008]
GeneCards Summary for AMN Gene
AMN (Amnion Associated Transmembrane Protein) is a Protein Coding gene. Diseases associated with AMN include megaloblastic anemia and methylmalonic aciduria and homocystinuria type cble. Among its related pathways are Disease and Metabolism.
UniProtKB/Swiss-Prot for AMN Gene
Necessary for efficient absorption of vitamin B12. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm (By similarity).