Aliases for C6orf25 Gene
External Ids for C6orf25 Gene
Previous GeneCards Identifiers for C6orf25 Gene
This gene is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. The protein encoded by this gene is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for C6orf25 Gene
C6orf25 (Chromosome 6 Open Reading Frame 25) is a Protein Coding gene. Diseases associated with C6orf25 include gray platelet syndrome and paraneoplastic pemphigus. GO annotations related to this gene include heparin binding.
UniProtKB/Swiss-Prot for C6orf25 Gene
Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide. Appears to operate in a calcium-independent manner. Isoform B is a putative inhibitory receptor. Isoform A may be its activating counterpart.