Aliases for CHD9 Gene
Aliases for CHD9 Gene
- Chromodomain Helicase DNA Binding Protein 9 2 3 5
- Peroxisomal Proliferator-Activated Receptor A-Interacting Complex 320 KDa Protein 3 4
- PPAR-Alpha-Interacting Complex Protein 320 KDa 3 4
- Chromatin-Related Mesenchymal Modulator 3 4
- ATP-Dependent Helicase CHD9 3 4
- Kismet Homolog 2 3 4
- PRIC320 3 4
- CHD-9 3 4
- CReMM 3 4
- KISH2 3 4
- Chromodomain-Helicase-DNA-Binding Protein 9 3
External Ids for CHD9 Gene
- HGNC: 25701
- Entrez Gene: 80205
- Ensembl: ENSG00000177200
- OMIM: 616936
- UniProtKB: Q3L8U1
Previous GeneCards Identifiers for CHD9 Gene
- GC16P051646
- GC16P051747
- GC16P038976
Summaries for CHD9 Gene
GeneCards Summary for CHD9 Gene
CHD9 (Chromodomain Helicase DNA Binding Protein 9) is a Protein Coding gene. Among its related pathways are Mitochondrial Gene Expression and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha). GO annotations related to this gene include nucleic acid binding and helicase activity. An important paralog of this gene is CHD7.
UniProtKB/Swiss-Prot for CHD9 Gene
-
Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T-rich DNA. Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis (By similarity).
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CHD9 Gene
Genomics for CHD9 Gene
Regulatory Elements for CHD9 Gene
Enhancers for CHD9 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH16G053207 | 2.3 | ENCODE dbSUPER | 11.8 | +154.3 | 154326 | 4.2 | HDGF PKNOX1 FOXA2 ATF1 ARNT ARID4B SIN3A FEZF1 YY1 CBX5 | CHD9 ENSG00000261291 ENSG00000280227 |
| GH16G053089 | 1.9 | FANTOM5 Ensembl ENCODE dbSUPER | 12 | +37.4 | 37359 | 6.1 | HDGF FOXA2 WRNIP1 SIN3A YY1 TCF12 ZNF121 CBX5 GATA2 FOS | CHD9 RBL2 GC16P053085 GC16M053158 |
| GH16G053097 | 1.4 | ENCODE dbSUPER | 11.9 | +44.3 | 44330 | 3.8 | HDGF PKNOX1 FOXA2 MLX CREB3L1 ARID4B SIN3A DMAP1 YY1 ZNF143 | CHD9 GC16P053085 GC16M053158 |
| GH16G053082 | 1.3 | Ensembl ENCODE dbSUPER | 12 | +30.2 | 30172 | 5.2 | TAL1 ETV1 ZNF133 ZIC2 RAD21 ZNF7 YY1 TCF12 POLR2A GATA2 | CHD9 GC16P053085 GC16M053158 |
| GH16G053078 | 1.3 | Ensembl ENCODE dbSUPER | 11.6 | +25.3 | 25254 | 3.1 | CTCF PKNOX1 ATF1 BACH1 SIN3A RAD21 ZNF316 FOS NR2F6 PRDM10 | CHD9 GC16P053085 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CHD9 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the CHD9 gene promoter:
Regulatory Element Products
Genomic Location for CHD9 Gene
- Chromosome:
- 16
- Start:
- 53,054,998 bp from pter
- End:
- 53,329,150 bp from pter
- Size:
- 274,153 bases
- Orientation:
- Plus strand
Genomic View for CHD9 Gene
Genes around CHD9 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16q12.2 by Ensembl
- 16q12.2 by Entrez Gene
- 16q12.2 by HGNC
CHD9 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CHD9 Gene
Proteins for CHD9 Gene
-
Protein details for CHD9 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q3L8U1-CHD9_HUMAN
- Recommended name:
- Chromodomain-helicase-DNA-binding protein 9
- Protein Accession:
- Q3L8U1
- B2RTU2
- B9ZVQ0
- O15025
- Q1WF12
- Q6DTK9
- Q9H9V7
- Q9UHM2
Protein attributes for CHD9 Gene
- Size:
- 2897 amino acids
- Molecular mass:
- 326022 Da
- Quaternary structure:
-
- Interacts with PPARA. Probably interacts with ESR1 and NR1I3.
- SequenceCaution:
-
- Sequence=AAF24170.1; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305}; Sequence=BAB14112.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for CHD9 Gene
Selected DME Specific Peptides for CHD9 Gene
- Q3L8U1:
-
- VLIFSQMVR
- PKQKRHRCRNPNKLD
- PVPRGRKGK
- GAEEKIL
- ILKPMMLRRLK
- IFDSDWNP
- KASFVAS
- RRGRRKNVEG
- MCRRVCR
- DEMGLGKT
- SRQMIQQYEM
- AVLQSMSG
- FCEEDIDQIL
- TITIESEG
- DFYRVVSTFG
- DEAHRLK
- TGTPLQN
- ETIIEVELT
- KDKRIQQKIKRFK
- LDILEDY
- ECFRVEKNLL
- MGLGKTIQ
- DSDWNPQ
- QKKYYRAILE
- QNLQNLQSLQ
- RADPALCFLE
- ITTFEMIL
- FNPDYVE
- SRRGRRPKS
- MLRRLKEDV
- AGGLGINL
- RCHRIGQ
- KAVKVYRL
- KQEKANRI
- YLVKWCSLPYE
- WPKDRVMINRLD
- PITEERASRTLYR
- CNKVLLRVRMLY
- NWEREFRTWT
- LLIGVFK
- NTMMELRKCCNHPYLI
- EDPEYKP
- QQRWTRRE
Post-translational modifications for CHD9 Gene
- Phosphorylated on serine and tyrosine residues.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for CHD9 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for CHD9
- Novus Biologicals Antibodies for CHD9
-
Abcam antibodies for CHD9
- Invitrogen Antibodies for CHD9
- antibodies-online Antibodies for CHD9: See all 9
- Search GeneTex for Antibodies for CHD9
-
Santa Cruz Biotechnology (SCBT) Antibodies for CHD9
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for CHD9
- Origene Custom Protein Services for CHD9
- Novus Biologicals proteins for CHD9
- Search GeneTex for Proteins for CHD9
-
Abcam proteins for CHD9
Assay Products
- antibodies-online Kits for CHD9: See all 3
Domains & Families for CHD9 Gene
Protein Domains for CHD9 Gene
Suggested Antigen Peptide Sequences for CHD9 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q3L8U1- Family:
-
- Belongs to the SNF2/RAD54 helicase family.
No data available for Gene Families for CHD9 Gene
Function for CHD9 Gene
Molecular function for CHD9 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- ATP + H(2)O = ADP + phosphate.
- UniProtKB/Swiss-Prot Function:
- Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T-rich DNA. Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis (By similarity).
Enzyme Numbers (IUBMB) for CHD9 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | -- |
| GO:0004386 | helicase activity | IEA | -- |
| GO:0005524 | ATP binding | IEA | -- |
| GO:0016787 | hydrolase activity | IEA | -- |
| GO:0016817 | hydrolase activity, acting on acid anhydrides | IEA | -- |
Phenotypes for CHD9 Gene
- MGI mutant phenotypes for CHD9:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CHD9:
Animal Models for CHD9 Gene
- MGI Knock Outs for CHD9:
-
- Chd9 tm1a(EUCOMM)Wtsi
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CHD9
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CHD9 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CHD9 gene
- Search ViGene Biosciences for CHD9
CRISPR Products
-
OriGene CRISPR knockouts for CHD9
-
Santa Cruz Biotechnology (SCBT) CRISPR for CHD9
- GenScript: Design CRISPR guide RNA sequences for CHD9
miRNA for CHD9 Gene
- miRTarBase miRNAs that target CHD9
-
- hsa-mir-210-3p (MIRT003181)
- hsa-mir-155-5p (MIRT020560)
- hsa-mir-7-5p (MIRT025670)
- hsa-mir-26b-5p (MIRT028901)
- hsa-let-7e-5p (MIRT051555)
- hsa-mir-17-5p (MIRT074888)
- hsa-mir-19a-3p (MIRT074889)
- hsa-mir-19b-3p (MIRT074890)
- hsa-mir-20a-5p (MIRT074891)
- hsa-mir-93-5p (MIRT074892)
- hsa-mir-106b-5p (MIRT074897)
- hsa-mir-20b-5p (MIRT074900)
- hsa-mir-519d-3p (MIRT074905)
- hsa-mir-22-3p (MIRT143443)
- hsa-mir-181a-5p (MIRT143445)
- hsa-mir-181b-5p (MIRT143446)
- hsa-mir-181c-5p (MIRT143447)
- hsa-mir-376a-5p (MIRT143452)
- hsa-mir-181d-5p (MIRT143461)
- hsa-mir-376a-2-5p (MIRT143462)
- hsa-mir-944 (MIRT143466)
- hsa-mir-664a-3p (MIRT143469)
- hsa-mir-2052 (MIRT143470)
- hsa-mir-1193 (MIRT143473)
- hsa-mir-4262 (MIRT143475)
- hsa-mir-3607-3p (MIRT143477)
- hsa-mir-3668 (MIRT143480)
- hsa-mir-3686 (MIRT143481)
- hsa-mir-3935 (MIRT143483)
- hsa-mir-4663 (MIRT143486)
- hsa-mir-4682 (MIRT143487)
- hsa-mir-8077 (MIRT143493)
- hsa-mir-433-3p (MIRT143520)
- hsa-mir-7154-5p (MIRT143558)
- hsa-mir-34b-3p (MIRT375371)
- hsa-mir-6809-3p (MIRT659526)
- hsa-mir-6833-3p (MIRT659527)
- hsa-mir-4768-5p (MIRT659528)
- hsa-mir-6873-3p (MIRT659529)
- hsa-mir-6794-3p (MIRT659530)
- hsa-mir-627-3p (MIRT659531)
- hsa-mir-4639-3p (MIRT659532)
- hsa-mir-342-3p (MIRT659533)
- hsa-mir-548c-3p (MIRT659534)
- hsa-mir-3163 (MIRT669041)
- hsa-mir-628-5p (MIRT704712)
- hsa-mir-7641 (MIRT704713)
- hsa-mir-3171 (MIRT704714)
- hsa-mir-139-5p (MIRT704715)
miRNA Products
- Search ViGene Biosciences for CHD9
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for CHD9
- Browse OriGene Inhibitory RNA Products For CHD9
-
ViGene Biosciences ready-to-package AAV shRNAs for CHD9 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CHD9
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CHD9
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CHD9
-
ViGene Biosciences adenoviral particle packaged cDNA for CHD9 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CHD9 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CHD9 gene
Flow Cytometry Products
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CHD9 Gene
Localization for CHD9 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CHD9 Gene
- Cytoplasm. Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 3 |
| plasma membrane | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005737 | cytoplasm | IEA | -- |
Pathways & Interactions for CHD9 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | BMAL1-CLOCK,NPAS2 activates circadian gene expression |
.68
|
|
| 2 | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | ||
| 3 | Regulation of cholesterol biosynthesis by SREBP (SREBF) | ||
| 4 | Gene Expression |
.48
|
|
| 5 | Metabolism |
.37
|
|
Pathways by source for CHD9 Gene
Interacting Proteins for CHD9 Gene
Selected Interacting proteins:
ENSP00000455307
Q3L8U1-CHD9_HUMAN
for CHD9 Gene via
STRING
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0016569 | covalent chromatin modification | IEA | -- |
| GO:0019216 | regulation of lipid metabolic process | TAS | -- |
| GO:0044255 | cellular lipid metabolic process | TAS | -- |
No data available for SIGNOR curated interactions for CHD9 Gene
Drugs & Compounds for CHD9 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| ADP |
|
Full agonist, Agonist | 58-64-0 |
|
Transcripts for CHD9 Gene
mRNA/cDNA for CHD9 Gene
- (21) REFSEQ mRNAs :
- (17) Additional mRNA sequences :
- (240) Selected AceView cDNA sequences:
- (21) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CHD9 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CHD9
-
Santa Cruz Biotechnology (SCBT) CRISPR for CHD9
- GenScript: Design CRISPR guide RNA sequences for CHD9
miRNA Products
- Search ViGene Biosciences for CHD9
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for CHD9
- Browse OriGene Inhibitory RNA Products For CHD9
-
ViGene Biosciences ready-to-package AAV shRNAs for CHD9 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CHD9
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CHD9
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 | ^ | 19a | · | 19b | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - |
| ExUns: | 20 | ^ | 21 | ^ | 22 | ^ | 23a | · | 23b | ^ | 24 | ^ | 25 | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30a | · | 30b | ^ | 31 | ^ | 32 | ^ | 33 | ^ | 34 | ^ | 35 | ^ | 36a | · | 36b | ^ | 37 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||||||||||||||||||||
| SP9: | |||||||||||||||||||||||||||||||||||||||||
| SP10: |
Expression for CHD9 Gene
This gene is overexpressed in Pancreatic juice (23.9), Heart (11.9), Prostate (10.0), Retina (8.5), and Peripheral blood mononuclear cells (6.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CHD9 Gene
NURSA nuclear receptor signaling pathways regulating expression of CHD9 Gene:
CHD9SOURCE GeneReport for Unigene cluster for CHD9 Gene:
Hs.59159mRNA Expression by UniProt/SwissProt for CHD9 Gene:
Q3L8U1-CHD9_HUMAN
Tissue specificity:
Widely expressed at low levels. In bone marrow, expression is restricted to osteoprogenitor cells adjacent to mature osteoblasts.
Evidence on tissue expression from TISSUES for CHD9 Gene
- Lung(4.8)
- Nervous system(4.7)
- Bone(4.6)
- Adrenal gland(4.2)
- Kidney(2)
Primer Products
-
OriGene qPCR primer pairs for CHD9
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for CHD9 Gene
Orthologs for CHD9 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CHD9 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | CHD9 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | CHD9 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| mouse (Mus musculus) |
Mammalia | Chd9 34 16 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | CHD9 35 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Chd9 34 |
|
||
| chicken (Gallus gallus) |
Aves | CHD9 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | CHD9 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | chd9 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | kis 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | chd-7 35 |
|
OneToMany |
- Species where no ortholog for CHD9 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for CHD9 Gene
(11) SIMAP similar genes for CHD9 Gene using alignment to 10 proteins:
Variants for CHD9 Gene
| SNP ID | Clin | Chr 16 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000004960 | -- | 53,254,972(+) | TTGGC(-/T)TTTTT | intron-variant | |
| rs1000024295 | -- | 53,129,311(+) | TGAAT(G/T)TGCAA | intron-variant, upstream-variant-2KB | |
| rs1000031390 | -- | 53,093,956(+) | CCATG(A/G)AGTCT | intron-variant | |
| rs1000069863 | -- | 53,076,354(+) | CAGAT(C/T)ACTTA | intron-variant | |
| rs1000076088 | -- | 53,124,191(+) | AGCAG(G/T)GTACC | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv2979n100 | CNV | loss | 25217958 |
| dgv521e214 | CNV | loss | 21293372 |
| esv1370771 | CNV | insertion | 17803354 |
| esv21460 | CNV | loss | 19812545 |
| esv2671644 | CNV | deletion | 23128226 |
| esv3582202 | CNV | loss | 25503493 |
| esv3582203 | CNV | loss | 25503493 |
| esv3638643 | CNV | gain | 21293372 |
| nsv1063647 | CNV | loss | 25217958 |
| nsv1066719 | CNV | loss | 25217958 |
| nsv476217 | CNV | novel sequence insertion | 20440878 |
| nsv510419 | OTHER | sequence alteration | 20534489 |
| nsv572617 | CNV | loss | 21841781 |
| nsv827652 | CNV | loss | 20364138 |
| nsv833232 | CNV | loss | 17160897 |
| nsv833233 | CNV | gain | 17160897 |
| nsv9443 | CNV | loss | 18304495 |
Residual Variation Intolerance Score:
0.566% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.75;
83.22% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CHD9 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CHD9
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CHD9 Gene
Disorders for CHD9 Gene
Relevant External Links for CHD9
No disorders were found for CHD9 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CHD9 Gene
Publications for CHD9 Gene
- Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9205841) Nagase T. … Ohara O. (DNA Res. 1997) 2 3 4 64
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4 64
- PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex. (PMID: 16554032) Surapureddi S. … Reddy J.K. (Biochem. Biophys. Res. Commun. 2006) 3 4 64
- Characterization and functional analysis of CReMM, a novel chromodomain helicase DNA-binding protein. (PMID: 16095617) Shur I. … Benayahu D. (J. Mol. Biol. 2005) 3 4 64
Products for CHD9 Gene
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- GenScript: Next-day shipping cDNA ORF clone for CHD9 in any vector
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- Novus Biologicals Antibodies for CHD9
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- antibodies-online Antibodies for CHD9: See all 9
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- ViGene Biosciences adenoviral particle packaged cDNA for CHD9 gene
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- Santa Cruz Biotechnology (SCBT) Antibodies for CHD9
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- Horizon Cell Lines for CHD9
- Cyagen custom Knockout/knockin (KOKI) mouse models for CHD9
- VectorBuilder custom plasmid, inducible vectors for CHD9
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CHD9
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CHD9 Gene
- (1) GeneCards
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- (50) eBioscience
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- (74) Cloud-Clone Corp.
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