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Aliases for NR4A3 Gene

Aliases for NR4A3 Gene

  • Nuclear Receptor Subfamily 4 Group A Member 3 2 3 5
  • Nuclear Receptor Subfamily 4, Group A, Member 3 2 3
  • Mitogen-Induced Nuclear Orphan Receptor 3 4
  • Neuron-Derived Orphan Receptor 1 3 4
  • Nuclear Hormone Receptor NOR-1 3 4
  • MINOR 3 4
  • CSMF 3 4
  • NOR1 3 4
  • CHN 3 4
  • TEC 3 4
  • Chondrosarcoma, Extraskeletal Myxoid, Fused To EWS 3
  • Translocated In Extraskeletal Chondrosarcoma 3

External Ids for NR4A3 Gene

Previous GeneCards Identifiers for NR4A3 Gene

  • GC09P093384
  • GC09P094327
  • GC09P096041
  • GC09P097963
  • GC09P099663
  • GC09P101623
  • GC09P102584
  • GC09P072183

Summaries for NR4A3 Gene

Entrez Gene Summary for NR4A3 Gene

  • This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

GeneCards Summary for NR4A3 Gene

NR4A3 (Nuclear Receptor Subfamily 4 Group A Member 3) is a Protein Coding gene. Diseases associated with NR4A3 include chondrosarcoma, extraskeletal myxoid and chondrosarcoma. Among its related pathways are Gene Expression and Signaling by GPCR. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. An important paralog of this gene is NR4A2.

UniProtKB/Swiss-Prot for NR4A3 Gene

  • Transcriptional activator that binds to regulatory elements in promoter regions in a cell- and response element (target)-specific manner. Induces gene expression by binding as monomers to the NR4A1 response element (NBRE) 5-AAAAGGTCA-3 site and as homodimers to the Nur response element (NurRE) site in the promoter of their regulated target genes (By similarity). Plays a role in the regulation of proliferation, survival and differentiation of many different cell types and also in metabolism and inflammation. Mediates proliferation of vascular smooth muscle, myeloid progenitor cell and type B pancreatic cells; promotes mitogen-induced vascular smooth muscle cell proliferation through transactivation of SKP2 promoter by binding a NBRE site (By similarity). Upon PDGF stimulation, stimulates vascular smooth muscle cell proliferation by regulating CCND1 and CCND2 expression. In islets, induces type B pancreatic cell proliferation through up-regulation of genes that activate cell cycle, as well as genes that cause degradation of the CDKN1A (By similarity). Negatively regulates myeloid progenitor cell proliferation by repressing RUNX1 in a NBRE site-independent manner. During inner ear, plays a role as a key mediator of the proliferative growth phase of semicircular canal development (By similarity). Mediates also survival of neuron and smooth muscle cells; mediates CREB-induced neuronal survival, and during hippocampus development, plays a critical role in pyramidal cell survival and axonal guidance. Is required for S phase entry of the cell cycle and survival of smooth muscle cells by inducing CCND1, resulting in RB1 phosphorylation. Binds to NBRE motif in CCND1 promoter, resulting in the activation of the promoter and CCND1 transcription (By similarity). Plays also a role in inflammation; upon TNF stimulation, mediates monocyte adhesion by inducing the expression of VCAM1 and ICAM1 by binding to the NBRE consensus site (By similarity) (PubMed:20558821). In mast cells activated by Fc-epsilon receptor cross-linking, promotes the synthesis and release of cytokines but impairs events leading to degranulation (By similarity). Plays also a role in metabolism; by modulating feeding behavior; and by playing a role in energy balance by inhibiting the glucocorticoid-induced orexigenic neuropeptides AGRP expression, at least in part by forming a complex with activated NR3C1 on the AGRP- glucocorticoid response element (GRE), and thus weakening the DNA binding activity of NR3C1. Upon catecholamines stimulation, regulates gene expression that controls oxidative metabolism in skeletal muscle (By similarity). Plays a role in glucose transport by regulating translocation of the SLC2A4 glucose transporter to the cell surface (PubMed:24022864). Finally, during gastrulation plays a crucial role in the formation of anterior mesoderm by controlling cell migration. Inhibits adipogenesis (By similarity). Also participates in cardiac hypertrophy by activating PARP1 (By similarity).

Gene Wiki entry for NR4A3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NR4A3 Gene

Genomics for NR4A3 Gene

Regulatory Elements for NR4A3 Gene

Promoters for NR4A3 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around NR4A3 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the NR4A3 gene promoter:

Genomic Location for NR4A3 Gene

Chromosome:
9
Start:
99,821,855 bp from pter
End:
99,866,893 bp from pter
Size:
45,039 bases
Orientation:
Plus strand

Genomic View for NR4A3 Gene

Genes around NR4A3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NR4A3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NR4A3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NR4A3 Gene

Proteins for NR4A3 Gene

  • Protein details for NR4A3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q92570-NR4A3_HUMAN
    Recommended name:
    Nuclear receptor subfamily 4 group A member 3
    Protein Accession:
    Q92570
    Secondary Accessions:
    • A2A3I7
    • Q12935
    • Q14979
    • Q16420
    • Q4VXA8
    • Q4VXA9
    • Q9UEK2
    • Q9UEK3

    Protein attributes for NR4A3 Gene

    Size:
    626 amino acids
    Molecular mass:
    68230 Da
    Quaternary structure:
    • Interacts with SIX3 (via homeobox); differentially regulates the transcriptional activities of NR4A3 (PubMed:12543801). Interacts with the constituents of DNA-PK heterotrimer PRKDC, XRCC6 and XRCC5; phosphorylates and prevents NR4A3 ubiquitinylation and degradation (PubMed:25852083). Interacts with NCOA2; potentiates the activity of the NR4A3. Interacts with NCOA1, NCOA3, MED1 and KAT2B. Interacts with EP300 and NCOA2; mediates the recruitment of MED1 in the coactivator complex (By similarity). Interacts with NR3C1 (via nuclear receptor DNA-binding domain); the interactions represses transcription activity of NR4A3 on the POMC promoter Nur response element (NurRE). Interacts with TRIM28; the interactions potentiates NR4A3 activity on NurRE promoter. Binds DNA as a monomer and homodimer. Interacts with PARP1; activates PARP1 by improving acetylation of PARP1 and suppressing the interaction between PARP1 and SIRT1 (By similarity).
    SequenceCaution:
    • Sequence=AAB02581.1; Type=Frameshift; Positions=4, 20; Evidence={ECO:0000305}; Sequence=AAB36006.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for NR4A3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for NR4A3 Gene

Proteomics data for NR4A3 Gene at MOPED

Post-translational modifications for NR4A3 Gene

Other Protein References for NR4A3 Gene

No data available for DME Specific Peptides for NR4A3 Gene

Domains & Families for NR4A3 Gene

Gene Families for NR4A3 Gene

Suggested Antigen Peptide Sequences for NR4A3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q92570

UniProtKB/Swiss-Prot:

NR4A3_HUMAN :
  • The AF-1 domain mediates transcription activation. The N-terminal region (1-292) directly interacts with the C-terminal LBD (380-627): the interaction is potentiated by AF-1-mediated recruitment of NCOA2.
  • Belongs to the nuclear hormone receptor family. NR4 subfamily.
Domain:
  • The AF-1 domain mediates transcription activation. The N-terminal region (1-292) directly interacts with the C-terminal LBD (380-627): the interaction is potentiated by AF-1-mediated recruitment of NCOA2.
  • Contains 1 nuclear receptor DNA-binding domain.
Family:
  • Belongs to the nuclear hormone receptor family. NR4 subfamily.
genes like me logo Genes that share domains with NR4A3: view

Function for NR4A3 Gene

Molecular function for NR4A3 Gene

GENATLAS Biochemistry:
nuclear receptor subfamily 4,group A,member 3, the steroid/thyroid receptor superfamily,with variants generated by alternative splicing,involved in extraskeletal and skeletal myxoid chondrosarcoma EMC with translocation t(9;22)(q22;q12) see EWS,EWSR,and in neural development processes
UniProtKB/Swiss-Prot Function:
Transcriptional activator that binds to regulatory elements in promoter regions in a cell- and response element (target)-specific manner. Induces gene expression by binding as monomers to the NR4A1 response element (NBRE) 5-AAAAGGTCA-3 site and as homodimers to the Nur response element (NurRE) site in the promoter of their regulated target genes (By similarity). Plays a role in the regulation of proliferation, survival and differentiation of many different cell types and also in metabolism and inflammation. Mediates proliferation of vascular smooth muscle, myeloid progenitor cell and type B pancreatic cells; promotes mitogen-induced vascular smooth muscle cell proliferation through transactivation of SKP2 promoter by binding a NBRE site (By similarity). Upon PDGF stimulation, stimulates vascular smooth muscle cell proliferation by regulating CCND1 and CCND2 expression. In islets, induces type B pancreatic cell proliferation through up-regulation of genes that activate cell cycle, as well as genes that cause degradation of the CDKN1A (By similarity). Negatively regulates myeloid progenitor cell proliferation by repressing RUNX1 in a NBRE site-independent manner. During inner ear, plays a role as a key mediator of the proliferative growth phase of semicircular canal development (By similarity). Mediates also survival of neuron and smooth muscle cells; mediates CREB-induced neuronal survival, and during hippocampus development, plays a critical role in pyramidal cell survival and axonal guidance. Is required for S phase entry of the cell cycle and survival of smooth muscle cells by inducing CCND1, resulting in RB1 phosphorylation. Binds to NBRE motif in CCND1 promoter, resulting in the activation of the promoter and CCND1 transcription (By similarity). Plays also a role in inflammation; upon TNF stimulation, mediates monocyte adhesion by inducing the expression of VCAM1 and ICAM1 by binding to the NBRE consensus site (By similarity) (PubMed:20558821). In mast cells activated by Fc-epsilon receptor cross-linking, promotes the synthesis and release of cytokines but impairs events leading to degranulation (By similarity). Plays also a role in metabolism; by modulating feeding behavior; and by playing a role in energy balance by inhibiting the glucocorticoid-induced orexigenic neuropeptides AGRP expression, at least in part by forming a complex with activated NR3C1 on the AGRP- glucocorticoid response element (GRE), and thus weakening the DNA binding activity of NR3C1. Upon catecholamines stimulation, regulates gene expression that controls oxidative metabolism in skeletal muscle (By similarity). Plays a role in glucose transport by regulating translocation of the SLC2A4 glucose transporter to the cell surface (PubMed:24022864). Finally, during gastrulation plays a crucial role in the formation of anterior mesoderm by controlling cell migration. Inhibits adipogenesis (By similarity). Also participates in cardiac hypertrophy by activating PARP1 (By similarity).
UniProtKB/Swiss-Prot Induction:
Induced by inflammatory stimuli in endothelial cells through an NF-kappa-B-dependent transactivation of the NR4A3 Promoter.

Gene Ontology (GO) - Molecular Function for NR4A3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004887 thyroid hormone receptor activity TAS 8570200
genes like me logo Genes that share ontologies with NR4A3: view
genes like me logo Genes that share phenotypes with NR4A3: view

Human Phenotype Ontology for NR4A3 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for NR4A3 Gene

MGI Knock Outs for NR4A3:

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for NR4A3 Gene

Localization for NR4A3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NR4A3 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for NR4A3 Gene COMPARTMENTS Subcellular localization image for NR4A3 gene
Compartment Confidence
nucleus 5
lysosome 2
vacuole 2
mitochondrion 1

No data available for Gene Ontology (GO) - Cellular Components for NR4A3 Gene

Pathways & Interactions for NR4A3 Gene

genes like me logo Genes that share pathways with NR4A3: view

SIGNOR curated interactions for NR4A3 Gene

Is activated by:
Is inactivated by:

Gene Ontology (GO) - Biological Process for NR4A3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription from RNA polymerase II promoter ISS --
GO:0001707 mesoderm formation IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006366 transcription from RNA polymerase II promoter IEA --
GO:0006367 transcription initiation from RNA polymerase II promoter TAS --
genes like me logo Genes that share ontologies with NR4A3: view

Drugs & Compounds for NR4A3 Gene

(1) Drugs for NR4A3 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(2) Additional Compounds for NR4A3 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with NR4A3: view

Transcripts for NR4A3 Gene

Unigene Clusters for NR4A3 Gene

Nuclear receptor subfamily 4, group A, member 3:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for NR4A3 Gene

No ASD Table

Relevant External Links for NR4A3 Gene

GeneLoc Exon Structure for
NR4A3
ECgene alternative splicing isoforms for
NR4A3

Expression for NR4A3 Gene

mRNA expression in normal human tissues for NR4A3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for NR4A3 Gene

This gene is overexpressed in Heart - Atrial Appendage (x6.1), Muscle - Skeletal (x4.8), Artery - Tibial (x4.7), and Adipose - Visceral (Omentum) (x4.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for NR4A3 Gene



SOURCE GeneReport for Unigene cluster for NR4A3 Gene Hs.279522

mRNA Expression by UniProt/SwissProt for NR4A3 Gene

Q92570-NR4A3_HUMAN
Tissue specificity: Isoform alpha is highly expressed in skeletal muscle. Isoform beta is highly expressed in skeletal muscle and low expressed in fetal brain and placenta.
genes like me logo Genes that share expression patterns with NR4A3: view

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues and Protein tissue co-expression partners for NR4A3 Gene

Orthologs for NR4A3 Gene

This gene was present in the common ancestor of animals.

Orthologs for NR4A3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia NR4A3 36
  • 100 (a)
OneToOne
NR4A3 35
  • 99.37 (n)
  • 99.53 (a)
cow
(Bos Taurus)
Mammalia NR4A3 36
  • 93 (a)
OneToOne
NR4A3 35
  • 92.31 (n)
  • 93.56 (a)
dog
(Canis familiaris)
Mammalia NR4A3 35
  • 91.37 (n)
  • 91.85 (a)
mouse
(Mus musculus)
Mammalia Nr4a3 16
Nr4a3 35
  • 88.96 (n)
  • 92.77 (a)
Nr4a3 36
  • 92 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia NR4A3 36
  • 80 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia NR4A3 36
  • 77 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Nr4a3 35
  • 88.66 (n)
  • 92.94 (a)
chicken
(Gallus gallus)
Aves NR4A3 35
  • 79.34 (n)
  • 81.49 (a)
NR4A3 36
  • 81 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia NR4A3 36
  • 77 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia nr4a3 35
  • 62.02 (n)
  • 61.62 (a)
Str.5118 35
zebrafish
(Danio rerio)
Actinopterygii nr4a3 36
  • 58 (a)
OneToOne
nr4a3 35
  • 60.78 (n)
  • 60.84 (a)
fruit fly
(Drosophila melanogaster)
Insecta Hr38 37
  • 62 (a)
Hr38 36
  • 27 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea nhr-6 36
  • 26 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 24 (a)
OneToMany
Species with no ortholog for NR4A3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for NR4A3 Gene

ENSEMBL:
Gene Tree for NR4A3 (if available)
TreeFam:
Gene Tree for NR4A3 (if available)

Paralogs for NR4A3 Gene

Paralogs for NR4A3 Gene

(4) SIMAP similar genes for NR4A3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with NR4A3: view

Variants for NR4A3 Gene

Sequence variations from dbSNP and Humsavar for NR4A3 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1131339 -- 99,865,020(+) TTTAA(A/G)AAATA utr-variant-3-prime
rs1526267 -- 99,827,463(-) ACCTC(A/G)TCCCC intron-variant, utr-variant-5-prime
rs1802660 -- 99,866,623(+) CAGAA(G/T)AGAAC utr-variant-3-prime
rs1918008 -- 99,824,109(-) GCTCC(G/T)GCTTG intron-variant
rs1918009 -- 99,823,766(-) CCAGG(C/G)AAAGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for NR4A3 Gene

Variant ID Type Subtype PubMed ID
nsv893621 CNV Gain 21882294
nsv528025 CNV Gain 19592680
nsv893622 CNV Loss 21882294
nsv831668 CNV Gain+Loss 17160897
esv1004519 CNV Insertion 20482838

Variation tolerance for NR4A3 Gene

Residual Variation Intolerance Score: 26.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.15; 84.68% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NR4A3 Gene

HapMap Linkage Disequilibrium report
NR4A3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NR4A3 Gene

Disorders for NR4A3 Gene

MalaCards: The human disease database

(6) MalaCards diseases for NR4A3 Gene - From: OMIM, GeneTests, Orphanet, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
chondrosarcoma, extraskeletal myxoid
  • extraskeletal myxoid chondrosarcoma
chondrosarcoma
  • chondrosarcoma of bone
ewing sarcoma
  • neuroepithelioma
myxoid chondrosarcoma
fetal adenoma
  • microfollicular adenoma
- elite association - COSMIC cancer census association via MalaCards
Search NR4A3 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

NR4A3_HUMAN
  • Ewing sarcoma (ES) [MIM:612219]: A highly malignant, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcoma family of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. They are considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiated form of the tumors. Note=The gene represented in this entry is involved in disease pathogenesis. A chromosomal aberration involving NR4A3 is found in patients with Erwing sarcoma. Translocation t(9;22)(q22-31;q11-12) with EWSR1.
  • Note=A chromosomal aberration involving NR4A3 is a cause of a form of extraskeletal myxoid chondrosarcomas (EMC). Translocation t(9;17)(q22;q11) with TAF2N.

Relevant External Links for NR4A3

Genetic Association Database (GAD)
NR4A3
Human Genome Epidemiology (HuGE) Navigator
NR4A3
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
NR4A3
genes like me logo Genes that share disorders with NR4A3: view

No data available for Genatlas for NR4A3 Gene

Publications for NR4A3 Gene

  1. The isolation and characterization of MINOR, a novel mitogen- inducible nuclear orphan receptor. (PMID: 8614405) Hedvat C.V. … Irving S.G. (Mol. Endocrinol. 1995) 2 3 4 23 67
  2. Fluorescence in situ hybridization analysis of extraskeletal myxoid chondrosarcomas using EWSR1 and NR4A3 probes. (PMID: 19775727) Noguchi H. … Hasegawa T. (Hum. Pathol. 2010) 3 23
  3. The NR4A orphan nuclear receptor NOR1 is induced by platelet-derived growth factor and mediates vascular smooth muscle cell proliferation. (PMID: 16945922) Nomiyama T. … Bruemmer D. (J. Biol. Chem. 2006) 3 23
  4. Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli. (PMID: 15964844) Pei L. … Tontonoz P. (J. Biol. Chem. 2005) 3 23
  5. Coexpression of NOR1 and SIX3 proteins in extraskeletal myxoid chondrosarcomas without detectable NR4A3 fusion genes. (PMID: 15262426) Hisaoka M. … Hashimoto H. (Cancer Genet. Cytogenet. 2004) 3 23

Products for NR4A3 Gene

Sources for NR4A3 Gene

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