Aliases for PRRC2A Gene
External Ids for PRRC2A Gene
Previous HGNC Symbols for PRRC2A Gene
Previous GeneCards Identifiers for PRRC2A Gene
A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This gene has microsatellite repeats which are associated with the age-at-onset of insulin-dependent diabetes mellitus (IDDM) and possibly thought to be involved with the inflammatory process of pancreatic beta-cell destruction during the development of IDDM. This gene is also a candidate gene for the development of rheumatoid arthritis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]
GeneCards Summary for PRRC2A Gene
PRRC2A (Proline-Rich Coiled-Coil 2A) is a Protein Coding gene. Diseases associated with PRRC2A include spondylolisthesis and coronary artery aneurysm. GO annotations related to this gene include poly(A) RNA binding. An important paralog of this gene is PRRC2B.
UniProtKB/Swiss-Prot for PRRC2A Gene
May play a role in the regulation of pre-mRNA splicing.