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Aliases for ZNF19 Gene

Aliases for ZNF19 Gene

  • Zinc Finger Protein 19 2 3 5
  • Zinc Finger Protein 19 (KOX 12) 2 3
  • Zinc Finger Protein KOX12 3 4
  • KOX12 3 4

External Ids for ZNF19 Gene

Previous GeneCards Identifiers for ZNF19 Gene

  • GC16U990061
  • GC16M072231
  • GC16M071217
  • GC16M071284
  • GC16M070065
  • GC16M057276

Summaries for ZNF19 Gene

Entrez Gene Summary for ZNF19 Gene

  • The protein encoded by this gene contains a zinc finger, a nucleic acid-binding domain present in many transcription factors. This gene is located in a region next to ZNF23, a gene also encoding a zinc finger protein, on chromosome 16. [provided by RefSeq, Jul 2008]

GeneCards Summary for ZNF19 Gene

ZNF19 (Zinc Finger Protein 19) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ENSG00000261611.

UniProtKB/Swiss-Prot for ZNF19 Gene

  • May be involved in transcriptional regulation.

Gene Wiki entry for ZNF19 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF19 Gene

Genomics for ZNF19 Gene

Regulatory Elements for ZNF19 Gene

Enhancers for ZNF19 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF19 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF19 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF19 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF19 Gene

71,464,555 bp from pter
71,565,089 bp from pter
100,535 bases
Minus strand

Genomic View for ZNF19 Gene

Genes around ZNF19 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF19 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF19 Gene

Proteins for ZNF19 Gene

  • Protein details for ZNF19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 19
    Protein Accession:
    Secondary Accessions:
    • A8K895
    • Q86Y66
    • Q8NDE2
    • Q96M79
    • Q96NE5

    Protein attributes for ZNF19 Gene

    458 amino acids
    Molecular mass:
    52449 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAA36814.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF19 Gene


neXtProt entry for ZNF19 Gene

Proteomics data for ZNF19 Gene at MOPED

Post-translational modifications for ZNF19 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF19 Gene

Domains & Families for ZNF19 Gene

Gene Families for ZNF19 Gene

Protein Domains for ZNF19 Gene

Suggested Antigen Peptide Sequences for ZNF19 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 10 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 10 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF19: view

Function for ZNF19 Gene

Molecular function for ZNF19 Gene

GENATLAS Biochemistry:
zinc finger protein 19 (KOX12) (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF19: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF19 Gene

Localization for ZNF19 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF19 Gene

Subcellular locations from

Jensen Localization Image for ZNF19 Gene COMPARTMENTS Subcellular localization image for ZNF19 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF19 Gene

Pathways & Interactions for ZNF19 Gene

SuperPathways for ZNF19 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF19: view

Pathways by source for ZNF19 Gene

2 Reactome pathways for ZNF19 Gene

Interacting Proteins for ZNF19 Gene

Gene Ontology (GO) - Biological Process for ZNF19 Gene


No data available for SIGNOR curated interactions for ZNF19 Gene

Drugs & Compounds for ZNF19 Gene

No Compound Related Data Available

Transcripts for ZNF19 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF19 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b · 7c
SP1: - - -
SP2: - - - -
SP4: -
SP5: - -
SP6: -

Relevant External Links for ZNF19 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF19 Gene

mRNA expression in normal human tissues for ZNF19 Gene

genes like me logo Genes that share expression patterns with ZNF19: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF19 Gene

Orthologs for ZNF19 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF19 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF19 35
  • 84.62 (n)
  • 79.69 (a)
(Canis familiaris)
Mammalia ZNF19 35
  • 87.82 (n)
  • 82.71 (a)
-- 36
  • 85 (a)
(Pan troglodytes)
Mammalia ZNF19 35
  • 99.34 (n)
  • 98.69 (a)
-- 36
  • 99 (a)
Species with no ortholog for ZNF19:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF19 Gene

Gene Tree for ZNF19 (if available)
Gene Tree for ZNF19 (if available)

Paralogs for ZNF19 Gene

Paralogs for ZNF19 Gene

(546) SIMAP similar genes for ZNF19 Gene using alignment to 10 proteins: Pseudogenes for ZNF19 Gene

genes like me logo Genes that share paralogs with ZNF19: view

Variants for ZNF19 Gene

Sequence variations from dbSNP and Humsavar for ZNF19 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs8050871 - 71,475,893(+) TCACA(C/G)TGATA reference, missense
rs10500557 - 71,475,876(+) AGGCT(A/C/T)GCCCA reference, missense
rs4275857 -- 71,488,125(+) gaggc(A/C/T)aaggt intron-variant
rs12935091 -- 71,491,305(+) ACTCT(A/G)TCACT upstream-variant-2KB
rs13330287 -- 71,488,368(+) aaaaa(A/G)aaaaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF19 Gene

Variant ID Type Subtype PubMed ID
nsv7285 OTHER Inversion 18451855

Variation tolerance for ZNF19 Gene

Residual Variation Intolerance Score: 34% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.24; 40.24% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF19 Gene

Disorders for ZNF19 Gene

Relevant External Links for ZNF19

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF19 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF19 Gene

Publications for ZNF19 Gene

  1. Characterization and mapping of human genes encoding zinc finger proteins. (PMID: 1946370) Bray P.L. … Dawid I.B. (Proc. Natl. Acad. Sci. U.S.A. 1991) 2 3 4 67
  2. Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes. (PMID: 1505991) Lichter P. … Ward D.C. (Genomics 1992) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF19 Gene

Sources for ZNF19 Gene