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Aliases for ZNF7 Gene

Aliases for ZNF7 Gene

  • Zinc Finger Protein 7 2 3
  • KOX4 3 4 6
  • Zinc Finger Protein 7 (KOX 4, Clone HF.16) 2 3
  • Zinc Finger Protein HF.16 3 4
  • Zinc Finger Protein KOX4 3 4
  • C2-H2 Type Zinc Finger Protein 3
  • Zinc Finger Protein-7 (KOX4) 3
  • Zinc Finger Protein Zfp30 3
  • HF.16 3
  • Zf30 3

External Ids for ZNF7 Gene

Summaries for ZNF7 Gene

GeneCards Summary for ZNF7 Gene

ZNF7 (Zinc Finger Protein 7) is a Protein Coding gene. An important paralog of this gene is ZNF630.

UniProtKB/Swiss-Prot for ZNF7 Gene

  • May be involved in transcriptional regulation

Gene Wiki entry for ZNF7 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF7 Gene

Genomics for ZNF7 Gene

Genomic Location for ZNF7 Gene

Start:
144,827,464 bp from pter
End:
144,847,509 bp from pter
Size:
20,046 bases
Orientation:
Plus strand

Genomic View for ZNF7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF7 Gene

Regulatory Elements for ZNF7 Gene

Proteins for ZNF7 Gene

  • Protein details for ZNF7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P17097-ZNF7_HUMAN
    Recommended name:
    Zinc finger protein 7
    Protein Accession:
    P17097
    Secondary Accessions:
    • B4DT08
    • D3DWN6
    • P17015
    • Q8N8Y4

    Protein attributes for ZNF7 Gene

    Size:
    686 amino acids
    Molecular mass:
    77887 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF7 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF7 Gene

Proteomics data for ZNF7 Gene at MOPED

Post-translational modifications for ZNF7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF7 Gene

Domains for ZNF7 Gene

Gene Families for ZNF7 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Graphical View of Domain Structure for InterPro Entry

P17097

UniProtKB/Swiss-Prot:

ZNF7_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • P17097
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • P17097
Similarity:
  • Contains 15 C2H2-type zinc fingers.:
    • P17097
genes like me logo Genes that share domains with ZNF7: view

Function for ZNF7 Gene

Molecular function for ZNF7 Gene

GENATLAS Biochemistry: zinc finger protein 7 (clone ZFP.16,KOX4),Kruppel-like
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF7: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF7 Gene

Localization for ZNF7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF7 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF7 Gene COMPARTMENTS Subcellular localization image for ZNF7 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF7: view

Pathways for ZNF7 Gene

SuperPathways for ZNF7 Gene

No Data Available

Interacting Proteins for ZNF7 Gene

Selected Interacting proteins: P17097-ZNF7_HUMAN for ZNF7 Gene via I2D

Gene Ontology (GO) - Biological Process for ZNF7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
GO:0007275 multicellular organismal development TAS 2106481
genes like me logo Genes that share ontologies with ZNF7: view

No data available for Pathways by source for ZNF7 Gene

Transcripts for ZNF7 Gene

Unigene Clusters for ZNF7 Gene

Zinc finger protein 7:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF7 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b
SP1: - - -
SP2: - - - -
SP3: - - -
SP4: - -

Relevant External Links for ZNF7 Gene

GeneLoc Exon Structure for
ZNF7
ECgene alternative splicing isoforms for
ZNF7

Expression for ZNF7 Gene

mRNA expression in normal human tissues for ZNF7 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for ZNF7 Gene

SOURCE GeneReport for Unigene cluster for ZNF7 Gene Hs.493218

mRNA Expression by UniProt/SwissProt for ZNF7 Gene

P17097-ZNF7_HUMAN
Tissue specificity: Ubiquitously present in many human cell lines of different embryological derivation
genes like me logo Genes that share expressions with ZNF7: view

No data available for mRNA differential expression in normal tissues for ZNF7 Gene

Orthologs for ZNF7 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF7 35
  • 99.09 (n)
  • 98.99 (a)
ZNF7 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF7 35
  • 81 (n)
  • 81.85 (a)
ZNF7 36
  • 78 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF7 35
  • 83.5 (n)
  • 83.11 (a)
ZNF7 36
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp7 35
  • 76.73 (n)
  • 71 (a)
Zfp7 16
Zfp7 36
  • 69 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF7 36
  • 55 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100910444 35
  • 81.41 (n)
  • 80.36 (a)
Species with no ortholog for ZNF7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF7 Gene

ENSEMBL:
Gene Tree for ZNF7 (if available)
TreeFam:
Gene Tree for ZNF7 (if available)

Paralogs for ZNF7 Gene

Selected SIMAP similar genes for ZNF7 Gene using alignment to 10 proteins:

Pseudogenes.org Pseudogenes for ZNF7 Gene

genes like me logo Genes that share paralogs with ZNF7: view

Variants for ZNF7 Gene

Sequence variations from dbSNP and Humsavar for ZNF7 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs963742 -- 144,835,665(-) ACATC(C/T)TCCAA intron-variant
rs1013084 -- 144,836,645(+) TTCAG(C/T)TTATT intron-variant
rs1619184 -- 144,834,876(-) gtagt(C/G)ccagc intron-variant
rs1627538 -- 144,826,297(+) CAGGT(G/T)GGGGC upstream-variant-2KB
rs1735154 -- 144,825,773(+) ATTGG(A/G)CTCAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF7 Gene

Variant ID Type Subtype PubMed ID
nsv891807 CNV Loss 21882294
nsv891897 CNV Loss 21882294
nsv522459 CNV Loss 19592680
nsv891925 CNV Loss 21882294
dgv7985n71 CNV Loss 21882294
nsv891929 CNV Loss 21882294
esv2506190 CNV Deletion 19546169
esv2674326 CNV Deletion 23128226
nsv469809 CNV Loss 16826518

Relevant External Links for ZNF7 Gene

HapMap Linkage Disequilibrium report
ZNF7

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF7 Gene

Disorders for ZNF7 Gene

Relevant External Links for ZNF7

Genetic Association Database (GAD)
ZNF7
Human Genome Epidemiology (HuGE) Navigator
ZNF7
genes like me logo Genes that share disorders with ZNF7: view

No data available for UniProtKB/Swiss-Prot for ZNF7 Gene

Publications for ZNF7 Gene

  1. cDNA isolation, expression analysis, and chromosomal localization of two human zinc finger genes. (PMID: 2106481) Lania L. … Pelicci P.-G. (Genomics 1990) 2 3 4
  2. Multiple genes encoding zinc finger domains are expressed in human T cells. (PMID: 2288909) Thiesen H.-J. (New Biol. 1990) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Genome-wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations-significant evidence for linkage on chromosome 4q in African Americans: the Family Investigation of Nephropathy and Diabetes Research Group. (PMID: 19795399) Malhotra A. … Hanson R.L. (Diabetes Metab. Res. Rev. 2009) 3 48

Products for ZNF7 Gene

Sources for ZNF7 Gene

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