Aliases for ZFP36 Gene
External Ids for ZFP36 Gene
Previous GeneCards Identifiers for ZFP36 Gene
GeneCards Summary for ZFP36 Gene
ZFP36 (ZFP36 Ring Finger Protein) is a Protein Coding gene. Among its related pathways are Gene Expression and ErbB1 downstream signaling. GO annotations related to this gene include poly(A) RNA binding and enzyme binding. An important paralog of this gene is ZFP36L2.
UniProtKB/Swiss-Prot for ZFP36 Gene
mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF). Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).