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Aliases for TRPV1 Gene

Aliases for TRPV1 Gene

  • Transient Receptor Potential Cation Channel, Subfamily V, Member 1 2 3
  • Vanilloid Receptor Subtype 1 2 3
  • Osm-9-Like TRP Channel 1 3 4
  • Capsaicin Receptor 3 4
  • OTRPC1 3 4
  • VR1 3 4
  • Transient Receptor Potential Cation Channel Subfamily V Member 1 3
  • Transient Receptor Potential Vanilloid 1a 3
  • Transient Receptor Potential Vanilloid 1b 3
  • Vanilloid Receptor 1 4
  • Capsaicin Receptor) 6
  • TrpV1 4

External Ids for TRPV1 Gene

Previous HGNC Symbols for TRPV1 Gene

  • VR1

Previous GeneCards Identifiers for TRPV1 Gene

  • GC17M003782
  • GC17M003419
  • GC17M003675
  • GC17M003415
  • GC17M003360
  • GC17M003469
  • GC17M003471

Summaries for TRPV1 Gene

Entrez Gene Summary for TRPV1 Gene

  • Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for TRPV1 Gene

TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1) is a Protein Coding gene. Diseases associated with TRPV1 include pulpitis and burning mouth syndrome. Among its related pathways are CREB Pathway and Ion channel transport. GO annotations related to this gene include calmodulin binding and calcium channel activity. An important paralog of this gene is TRPV2.

UniProtKB/Swiss-Prot for TRPV1 Gene

  • Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Can be activated by endogenous compounds, including 12-hydroperoxytetraenoic acid and bradykinin. Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects. Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis (By similarity). Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca(2+)-dependent outward rectification, followed by a long-lasting refractory state. Mild extracellular acidic pH (6.5) potentiates channel activation by noxious heat and vanilloids, whereas acidic conditions (pH <6) directly activate the channel.

Tocris Summary for TRPV1 Gene

  • Vanilloids are a group of compounds, structurally related to capsaicin, thought to exert their actions via vanilloid receptors. The vanilloid receptor family (TRPV) is a subgroup of the transient receptor potential (TRP) superfamily of ion channels, and six members (TRPV1-6) have so far been identified. The six vanilloid receptor members have been divided into four groups on the basis of structure and function: TRPV1/2, TRPV3, TRPV4 and TRPV5/6. TRPV1-4 are thermosensitive, non-selective cation channels that exist as tetrameric complexes. They are activated by a range of stimuli including heat, protons, lipids and changes in osmolarity or pressure. TRPV5-6 are calcium selective channels that are involved in the absorption and reabsorption of calcium across intestinal and renal epithelia. It has been proposed that cannabinoids are endogenous ligands for vanilloid receptors. Furthermore, adenosine has been shown to be an endogenous TRPV1 ligand and TRPV4 is activated by anandamide and arachidonic acid.

Gene Wiki entry for TRPV1 Gene

No data available for PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRPV1 Gene

Genomics for TRPV1 Gene

Regulatory Elements for TRPV1 Gene

Transcription factor binding sites by QIAGEN in the TRPV1 gene promoter:

Genomic Location for TRPV1 Gene

Start:
3,565,444 bp from pter
End:
3,609,411 bp from pter
Size:
43,968 bases
Orientation:
Minus strand

Genomic View for TRPV1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TRPV1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRPV1 Gene

Proteins for TRPV1 Gene

  • Protein details for TRPV1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NER1-TRPV1_HUMAN
    Recommended name:
    Transient receptor potential cation channel subfamily V member 1
    Protein Accession:
    Q8NER1
    Secondary Accessions:
    • A2RUA9
    • Q3LU47
    • Q9H0G9
    • Q9H303
    • Q9H304
    • Q9NQ74
    • Q9NY22

    Protein attributes for TRPV1 Gene

    Size:
    839 amino acids
    Molecular mass:
    94956 Da
    Quaternary structure:
    • Homotetramer. Interacts with TRPV3 (PubMed:12077606). Interacts with CALM, PRKCM and CSK. Interacts with PRKCG and NTRK1, probably by forming a trimeric complex (By similarity). Interacts with PIRT (By similarity). Interacts with TMEM100 (By similarity).
    Miscellaneous:
    • Responses evoked by low pH and heat, and capsaicin can be antagonized by capsazepine
    SequenceCaution:
    • Sequence=AAG43467.1; Type=Frameshift; Positions=498; Evidence={ECO:0000305};

    Alternative splice isoforms for TRPV1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TRPV1 Gene

Proteomics data for TRPV1 Gene at MOPED

Post-translational modifications for TRPV1 Gene

  • Phosphorylation by PKA reverses capsaicin-induced dephosphorylation at multiple sites, probably including Ser-117 as a major phosphorylation site. Phoshphorylation by CAMKII seems to regulate binding to vanilloids. Phosphorylated and modulated by PRKCE, PRKCM and probably PRKCZ. Dephosphorylation by calcineurin seems to lead to receptor desensitization and phosphorylation by CAMKII recovers activity (By similarity).
  • Glycosylation at Asn604
  • Modification sites at PhosphoSitePlus

Other Protein References for TRPV1 Gene

Antibody Products

  • R&D Systems Antibodies for TRPV1 (Vanilloid R1/TRPV1)

No data available for DME Specific Peptides for TRPV1 Gene

Domains for TRPV1 Gene

Gene Families for TRPV1 Gene

HGNC:
  • ANKRD :Ankyrin repeat domain containing
  • TRP :Voltage-gated ion channels / Transient receptor potential cation channels
IUPHAR :

Graphical View of Domain Structure for InterPro Entry

Q8NER1

UniProtKB/Swiss-Prot:

TRPV1_HUMAN :
  • Q8NER1
Domain:
  • The association domain (AD) is necessary for self-association.
Family:
  • Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV1 sub-subfamily.
Similarity:
  • Contains 6 ANK repeats.
genes like me logo Genes that share domains with TRPV1: view

Function for TRPV1 Gene

Molecular function for TRPV1 Gene

UniProtKB/Swiss-Prot EnzymeRegulation: Channel activity is activated via the interaction with PIRT and phosphatidylinositol 4,5-bisphosphate (PIP2). Both PIRT and PIP2 are required to activate channel activity (By similarity). The channel is sensitized by ATP binding. Repeated stimulation with capsaicin gives rise to progressively smaller responses, due to desensitization. This desensitization is triggered by the influx of calcium ions and is inhibited by elevated ATP levels. Ca(2+) and CALM displace ATP from its binding site and trigger a conformation change that leads to a closed, desensitized channel. Intracellular PIP2 inhibits desensitization. The double-knot toxin (DkTx) from the Chinese earth tiger tarantula activates the channel and traps it in an open conformation (By similarity).
UniProtKB/Swiss-Prot Function: Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Can be activated by endogenous compounds, including 12-hydroperoxytetraenoic acid and bradykinin. Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects. Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis (By similarity). Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca(2+)-dependent outward rectification, followed by a long-lasting refractory state. Mild extracellular acidic pH (6.5) potentiates channel activation by noxious heat and vanilloids, whereas acidic conditions (pH <6) directly activate the channel.

Gene Ontology (GO) - Molecular Function for TRPV1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity ISS --
GO:0005216 ion channel activity --
GO:0005231 excitatory extracellular ligand-gated ion channel activity ISS --
GO:0005262 calcium channel activity TAS 9349813
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with TRPV1: view
genes like me logo Genes that share phenotypes with TRPV1: view

Animal Models for TRPV1 Gene

MGI Knock Outs for TRPV1:

Animal Model Products

CRISPR Products

miRNA for TRPV1 Gene

miRTarBase miRNAs that target TRPV1

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targeting and HOMER Transcription for TRPV1 Gene

Localization for TRPV1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRPV1 Gene

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell projection, dendritic spine membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Mostly, but not exclusively expressed in postsynaptic dendritic spines. {ECO:0000250}.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TRPV1 Gene COMPARTMENTS Subcellular localization image for TRPV1 gene
Compartment Confidence
plasma membrane 5
cytoskeleton 2
cytosol 2
extracellular 2
nucleus 2
endoplasmic reticulum 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for TRPV1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane TAS 9349813
GO:0016021 integral component of membrane IDA 123456
GO:0030054 cell junction IEA --
GO:0031226 intrinsic component of plasma membrane ISS --
genes like me logo Genes that share ontologies with TRPV1: view

Pathways for TRPV1 Gene

genes like me logo Genes that share pathways with TRPV1: view

PCR Array Products

  • Pathway & Disease-focused RT² Profiler PCR Arrays

Gene Ontology (GO) - Biological Process for TRPV1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport TAS 9349813
GO:0006811 ion transport --
GO:0007166 cell surface receptor signaling pathway TAS 9349813
GO:0007635 chemosensory behavior TAS 9349813
GO:0034220 ion transmembrane transport TAS --
genes like me logo Genes that share ontologies with TRPV1: view

Compounds for TRPV1 Gene

(5) Tocris Compounds for TRPV1 Gene

Compound Action Cas Number
AMG 9810 Potent and selective, competitive antagonist of TRPV1 [545395-94-6]
Anandamide Endogenous CB receptor agonist [94421-68-8]
Anandamide (in Tocrisolve� 100) Endogenous CB receptor agonist (in water-soluble emulsion) [94421-68-8]
Capsazepine Vanilloid receptor antagonist; also activator of ENaCdelta [138977-28-3]
HC 067047 Potent and selective TRPV4 antagonist [883031-03-6]

(1) HMDB Compounds for TRPV1 Gene

Compound Synonyms Cas Number PubMed IDs
Calcium
  • Ca
7440-70-2

(3) Drugbank Compounds for TRPV1 Gene

Compound Synonyms Cas Number Type Actions PubMed IDs
Alpha-Linolenic Acid
  • (9Z,12Z,15Z)-Octadecatrienoic acid
463-40-1 target
Aspartame
  • 1-Methyl N-L-alpha-aspartyl-L-phenylalanate
22839-47-0 target inducer
Icosapent
  • Eicosapentaenoic acid
10417-94-4 target inducer

(34) IUPHAR Ligand for TRPV1 Gene

Ligand Type Action Affinity Pubmed IDs
AMG517 Channel blocker None 9
[3H]A778317 None None 8.5
SB705498 Channel blocker None 8.5
AMG628 Channel blocker None 8.4
5-iodoresiniferatoxin Channel blocker None 8.4
A425619 Channel blocker None 8.3
A778317 Channel blocker None 8.3
BCTC Channel blocker None 8.2
6-iodo-nordihydrocapsaicin Channel blocker None 8
JYL1421 Channel blocker None 8
SB366791 Channel blocker None 7.7
capsazepine Pore Blocker Antagonist 7.4
JNJ17203212 Channel blocker None 7.2
H+ (extracellular) Activator None 5.4
piperine Activator Agonist 4.4
ruthenium red Channel blocker None
camphor Activator None
resiniferatoxin Activator None
[125I]resiniferatoxin None None
capsaicin Activator None
allicin Channel blocker None
phenylacetylrinvanil Activator None
15S-HPETE Activator None
12S-HPETE Activator None
DkTx Activator Irreversible agonist
[3H]resiniferatoxin None None
2-APB Channel blocker None
SB452533 Channel blocker None
diphenylboronic anhydride Activator None
NADA Channel blocker None
olvanil Activator None
LTB4 Activator None
5S-HETE Activator None
anandamide Channel blocker None

(58) Novoseek inferred chemical compound relationships for TRPV1 Gene

Compound -log(P) Hits PubMed IDs
capsaicin 96.1 258
capsazepine 95.3 95
resiniferatoxin 93.8 56
ppahv 89.9 10
n-oleoyl dopamine 87.5 5
genes like me logo Genes that share compounds with TRPV1: view

Transcripts for TRPV1 Gene

Unigene Clusters for TRPV1 Gene

Transient receptor potential cation channel, subfamily V, member 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TRPV1

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for TRPV1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRPV1 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17a · 17b · 17c · 17d
SP1: - - -
SP2: -
SP3: - -
SP4: - -
SP5: - - -
SP6:

Relevant External Links for TRPV1 Gene

GeneLoc Exon Structure for
TRPV1
ECgene alternative splicing isoforms for
TRPV1

Expression for TRPV1 Gene

mRNA expression in normal human tissues for TRPV1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TRPV1 Gene

This gene is overexpressed in Artery - Tibial (6.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TRPV1 Gene

SOURCE GeneReport for Unigene cluster for TRPV1 Gene Hs.655380

mRNA Expression by UniProt/SwissProt for TRPV1 Gene

Q8NER1-TRPV1_HUMAN
Tissue specificity: Widely expressed at low levels. Expression is elevated in dorsal root ganglia. In skin, expressed in cutaneous sensory nerve fibers, mast cells, epidermal keratinocytes, dermal blood vessels, the inner root sheet and the infundibulum of hair follicles, differentiated sebocytes, sweat gland ducts, and the secretory portion of eccrine sweat glands (at protein level).
genes like me logo Genes that share expressions with TRPV1: view

In Situ Assay Products

Orthologs for TRPV1 Gene

This gene was present in the common ancestor of animals.

Orthologs for TRPV1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 99 (a)
OneToMany
TRPV1 35
  • 99.18 (n)
  • 99.35 (a)
cow
(Bos Taurus)
Mammalia -- 36
  • 87 (a)
OneToMany
TRPV1 35
  • 88.1 (n)
  • 87.31 (a)
dog
(Canis familiaris)
Mammalia TRPV1 35
  • 87.95 (n)
  • 89.5 (a)
TRPV1 36
  • 89 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Trpv1 35
  • 85.76 (n)
  • 86.99 (a)
Trpv1 16
Trpv1 36
  • 87 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 76 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Trpv1 35
  • 85.9 (n)
  • 86.14 (a)
chicken
(Gallus gallus)
Aves TRPV1 35
  • 69.06 (n)
  • 70.06 (a)
TRPV1 36
  • 66 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 70 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia trpv1 35
  • 64.47 (n)
  • 64.17 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10404 35
zebrafish
(Danio rerio)
Actinopterygii trpv1 35
  • 59.76 (n)
  • 52.19 (a)
trpv1 36
  • 44 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta iav 36
  • 14 (a)
ManyToMany
nan 36
  • 19 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea ocr-1 36
  • 18 (a)
ManyToMany
ocr-2 36
  • 18 (a)
ManyToMany
ocr-3 36
  • 19 (a)
ManyToMany
ocr-4 36
  • 20 (a)
ManyToMany
osm-9 36
  • 17 (a)
ManyToMany
osm-9 37
  • 27 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 25 (a)
ManyToMany
-- 36
  • 21 (a)
ManyToMany
Species with no ortholog for TRPV1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TRPV1 Gene

ENSEMBL:
Gene Tree for TRPV1 (if available)
TreeFam:
Gene Tree for TRPV1 (if available)

Paralogs for TRPV1 Gene

Paralogs for TRPV1 Gene

genes like me logo Genes that share paralogs with TRPV1: view

Variants for TRPV1 Gene

Sequence variations from dbSNP and Humsavar for TRPV1 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs150845 -- 3,605,235(-) CACCA(C/T)GCCAG intron-variant
rs150846 -- 3,591,574(-) GATGG(C/T)GTCTA intron-variant
rs150908 -- 3,581,074(+) AGACA(A/G)GAAGG intron-variant
rs150915 -- 3,590,575(-) TCTCA(A/G)GACCT intron-variant
rs161363 -- 3,568,887(+) aaata(C/T)aaaaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TRPV1 Gene

Variant ID Type Subtype PubMed ID
nsv907553 CNV Loss 21882294
nsv526175 CNV Gain 19592680
dgv3042n71 CNV Loss 21882294
nsv907565 CNV Loss 21882294
nsv516676 CNV Gain+Loss 19592680
esv2662311 CNV Deletion 23128226
nsv907567 CNV Gain 21882294
nsv907568 CNV Loss 21882294
esv2665638 CNV Deletion 23128226
esv2715530 CNV Deletion 23290073
esv2639824 CNV Insertion 19546169
esv2662762 CNV Deletion 23128226
dgv358n27 CNV Loss 19166990

Relevant External Links for TRPV1 Gene

HapMap Linkage Disequilibrium report
TRPV1
Human Gene Mutation Database (HGMD)
TRPV1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRPV1 Gene

Disorders for TRPV1 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (8) Diseases for TRPV1 Gene including...

Search for TRPV1 Gene in MalaCards »

(5) University of Copenhagen DISEASES for TRPV1 Gene

(34) Novoseek inferred disease relationships for TRPV1 Gene

Disease -log(P) Hits PubMed IDs
hyperalgesia 82 59
bladder diseases 61.7 1
inflammation 52.3 53
functional dyspepsia 48.9 1
diabetic neuropathies 39.9 4

Relevant External Links for TRPV1

Genetic Association Database (GAD)
TRPV1
Human Genome Epidemiology (HuGE) Navigator
TRPV1
genes like me logo Genes that share disorders with TRPV1: view

No data available for UniProtKB/Swiss-Prot for TRPV1 Gene

Publications for TRPV1 Gene

  1. The capsaicin receptor: a heat-activated ion channel in the pain pathway. (PMID: 9349813) Caterina M.J. … Julius D. (Nature 1997) 2 3 23
  2. Pharmacological differences between human and rat vanilloid receptor 1 (VR1). (PMID: 11226139) McIntyre P. … James I. (Br. J. Pharmacol. 2001) 3 4 23
  3. The tissue distribution and functional characterization of human VR1. (PMID: 11243859) Cortright D.N. … White G. (Biochem. Biophys. Res. Commun. 2001) 3 4 23
  4. Cloning and functional expression of a human orthologue of rat vanilloid receptor-1. (PMID: 11050376) Hayes P. … Davis J.B. (Pain 2000) 3 4 23
  5. Molecular determinants of vanilloid sensitivity in TRPV1. (PMID: 14996838) Gavva N.R. … Treanor J.J. (J. Biol. Chem. 2004) 3 4 23

Products for TRPV1 Gene

Sources for TRPV1 Gene

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