Aliases for USF2 Gene
External Ids for USF2 Gene
Previous GeneCards Identifiers for USF2 Gene
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for USF2 Gene
USF2 (Upstream Transcription Factor 2, C-Fos Interacting) is a Protein Coding gene. Among its related pathways are Validated transcriptional targets of AP1 family members Fra1 and Fra2. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and sequence-specific DNA binding. An important paralog of this gene is USF1.
UniProtKB/Swiss-Prot for USF2 Gene
Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5-CACGTG-3) that is found in a variety of viral and cellular promoters