Aliases for TSPAN4 Gene
External Ids for TSPAN4 Gene
Previous HGNC Symbols for TSPAN4 Gene
Previous GeneCards Identifiers for TSPAN4 Gene
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for TSPAN4 Gene
TSPAN4 (Tetraspanin 4) is a Protein Coding gene. Diseases associated with TSPAN4 include congenital hypomyelination neuropathy. GO annotations related to this gene include integrin binding and antigen binding. An important paralog of this gene is TSPAN9.