Aliases for TSPAN6 Gene
External Ids for TSPAN6 Gene
Previous HGNC Symbols for TSPAN6 Gene
Previous GeneCards Identifiers for TSPAN6 Gene
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing. [provided by RefSeq, Jul 2013]
GeneCards Summary for TSPAN6 Gene
TSPAN6 (Tetraspanin 6) is a Protein Coding gene. Diseases associated with TSPAN6 include Epileptic Encephalopathy, Early Infantile, 9. GO annotations related to this gene include signal transducer activity. An important paralog of this gene is TSPAN7.