Aliases for TSPAN7 Gene
External Ids for TSPAN7 Gene
Previous HGNC Symbols for TSPAN7 Gene
Previous GeneCards Identifiers for TSPAN7 Gene
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked cognitive disability and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. [provided by RefSeq, Jul 2008]
GeneCards Summary for TSPAN7 Gene
TSPAN7 (Tetraspanin 7) is a Protein Coding gene. Diseases associated with TSPAN7 include X-Linked Non-Specific Intellectual Disability and Miliaria Rubra. Among its related pathways are Cell surface interactions at the vascular wall and Response to elevated platelet cytosolic Ca2+. An important paralog of this gene is ENSG00000250349.
UniProtKB/Swiss-Prot for TSPAN7 Gene
May be involved in cell proliferation and cell motility.