Aliases for TFE3 Gene
Aliases for TFE3 Gene
External Ids for TFE3 Gene
- HGNC: 11752
- Entrez Gene: 7030
- Ensembl: ENSG00000068323
- OMIM: 314310
- UniProtKB: P19532
Previous GeneCards Identifiers for TFE3 Gene
- GC0XM047669
- GC0XM047127
- GC0XM047912
- GC0XM048642
- GC0XM048771
- GC0XM048886
- GC0XM046545
Summaries for TFE3 Gene
-
This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
GeneCards Summary for TFE3 Gene
TFE3 (Transcription Factor Binding To IGHM Enhancer 3) is a Protein Coding gene. Diseases associated with TFE3 include Renal Cell Carcinoma, Papillary and Alveolar Soft-Part Sarcoma. Among its related pathways are Mitophagy - animal and Transcriptional misregulation in cancer. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcription regulatory region DNA binding. An important paralog of this gene is MITF.
UniProtKB/Swiss-Prot for TFE3 Gene
-
Transcription factor that specifically recognizes and binds E-box sequences (5-CANNTG-3). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TFE3 Gene
Genomics for TFE3 Gene
Regulatory Elements for TFE3 Gene
Enhancers for TFE3 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH0XG049037 | 1.4 | ENCODE dbSUPER | 5 | +2.4 | 2386 | 7.0 | HDGF FOXA2 PKNOX1 ARNT ARID4B SIN3A DMAP1 FEZF1 ZNF2 ZBTB7B | PRAF2 OTUD5 RNU6-722P SLC38A5 TFE3 PLP2 GC0XM049007 |
| GH0XG048933 | 2 | FANTOM5 Ensembl ENCODE dbSUPER | 3.4 | +105.0 | 105017 | 9.7 | HDGF FOXA2 PKNOX1 ARNT AGO1 ZFP64 WRNIP1 ARID4B SIN3A DMAP1 | PQBP1 WAS OTUD5 SLC35A2 TIMM17B PIM2 TBC1D25 ENSG00000204620 ENSG00000228343 FOXP3 |
| GH0XG049071 | 1 | ENCODE | 4.7 | -29.8 | -29835 | 3.7 | PKNOX1 AGO1 SIN3A YY1 ETS1 GLIS2 ZNF143 KLF7 SP3 YY2 | CCDC120 GPKOW TFE3 PRAF2 GC0XP049093 |
| GH0XG049034 | 0.9 | ENCODE | 4.6 | +8.9 | 8907 | 1.1 | AGO1 ARID4B SIN3A GLIS2 ZNF766 SP3 REST ZNF518A SREBF1 ZNF579 | TFE3 GC0XM049007 |
| GH0XG048667 | 0.5 | FANTOM5 | 4.3 | +375.8 | 375824 | 0.2 | ZNF341 CEBPB KDM1A | WAS OTUD5 TFE3 GRIPAP1 PIM2 RBM3 PIR44416 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around TFE3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for TFE3 Gene
- Chromosome:
- X
- Start:
- 49,028,726 bp from pter
- End:
- 49,043,517 bp from pter
- Size:
- 14,792 bases
- Orientation:
- Minus strand
Genomic View for TFE3 Gene
Genes around TFE3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xp11.23 by Ensembl
- Xp11.23 by Entrez Gene
- Xp11.23 by HGNC
TFE3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TFE3 Gene
Proteins for TFE3 Gene
-
Protein details for TFE3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P19532-TFE3_HUMAN
- Recommended name:
- Transcription factor E3
- Protein Accession:
- P19532
- A8MZL6
- Q5JU74
- Q92757
- Q92758
- Q99964
Protein attributes for TFE3 Gene
- Size:
- 575 amino acids
- Molecular mass:
- 61521 Da
- Quaternary structure:
-
- Homodimer and heterodimer; with TFEB or MITF.
- SequenceCaution:
-
- Sequence=CAA35714.1; Type=Frameshift; Positions=557; Evidence={ECO:0000305}; Sequence=CAA65800.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Protein Expression for TFE3 Gene
Post-translational modifications for TFE3 Gene
- Sumoylated; does not affect dimerization with MITF.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for TFE3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Cell Signaling Technology (CST) Antibodies for TFE3 (TFE3)
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-
Abcam antibodies for TFE3
-
Cloud-Clone Corp. Antibodies for TFE3
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- antibodies-online Antibodies for TFE3: See all 108
- GeneTex TFE3 antibody for TFE3
Protein Products
-
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-
Cloud-Clone Corp. Proteins for TFE3
- antibodies-online Proteins for TFE3: See all 7
- Search antibodies-online for peptides
- Search GeneTex for Proteins for TFE3
-
Abcam proteins for TFE3
No data available for DME Specific Peptides for TFE3 Gene
Domains & Families for TFE3 Gene
Gene Families for TFE3 Gene
Protein Domains for TFE3 Gene
Suggested Antigen Peptide Sequences for TFE3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P19532- Family:
-
- Belongs to the MiT/TFE family.
Function for TFE3 Gene
Molecular function for TFE3 Gene
- GENATLAS Biochemistry:
- transcription factor,binding IGH enhancer motif muE3 (see also RCCPX)
- UniProtKB/Swiss-Prot Function:
- Transcription factor that specifically recognizes and binds E-box sequences (5-CANNTG-3). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | IEA | -- |
| GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | IEA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003700 | transcription factor activity, sequence-specific DNA binding | ISS,NAS | -- |
| GO:0044212 | transcription regulatory region DNA binding | ISS | -- |
Phenotypes for TFE3 Gene
- MGI mutant phenotypes for TFE3:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for TFE3:
Animal Models for TFE3 Gene
- MGI Knock Outs for TFE3:
-
- Tfe3 tm1Est
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for TFE3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for TFE3 gene
- Search ViGene Biosciences for TFE3
CRISPR Products
-
OriGene CRISPR knockouts for TFE3
-
Applied Biological Materials CRISPR for TFE3
-
Santa Cruz Biotechnology (SCBT) CRISPR for TFE3
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miRNA for TFE3 Gene
- miRTarBase miRNAs that target TFE3
miRNA Products
- Search ViGene Biosciences for TFE3
Inhibitory RNA Products
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-
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Clone Products
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for TFE3
-
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-
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-
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No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for TFE3 Gene
Localization for TFE3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TFE3 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| cytoskeleton | 2 |
| extracellular | 1 |
| mitochondrion | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IMP | 21209915 |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for TFE3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Mitophagy - animal | ||
| 2 | Transcriptional misregulation in cancer | ||
| 3 | E2F transcription factor network | ||
| 4 | Regulation of nuclear SMAD2/3 signaling | ||
| 5 | TGF-beta Receptor Signaling (WikiPathways) | ||
Pathways by source for TFE3 Gene
3 BioSystems pathways for TFE3 Gene
2 KEGG pathways for TFE3 Gene
Interacting Proteins for TFE3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002250 | adaptive immune response | IEA | -- |
| GO:0002376 | immune system process | IEA | -- |
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006366 | transcription from RNA polymerase II promoter | IEA | -- |
No data available for SIGNOR curated interactions for TFE3 Gene
Transcripts for TFE3 Gene
mRNA/cDNA for TFE3 Gene
- (2) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (193) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for TFE3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for TFE3
-
Applied Biological Materials CRISPR for TFE3
-
Santa Cruz Biotechnology (SCBT) CRISPR for TFE3
- GenScript: Design CRISPR guide RNA sequences for TFE3
miRNA Products
- Search ViGene Biosciences for TFE3
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for TFE3
- Browse OriGene Inhibitory RNA Products For TFE3
-
ViGene Biosciences ready-to-package AAV shRNAs for TFE3 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for TFE3
- VectorBuilder custom plasmid, inducible vectors for TFE3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TFE3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | · | 4d | · | 4e | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||||||||||||||
| SP8: |
Expression for TFE3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
- Hematopoietic Bone Marrow
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
- Thyroid (Endocrine System)
- Intestine (Gastrointestinal Tract)
- Ovary (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for TFE3 Gene
This gene is overexpressed in Whole Blood (x4.6).
This gene is overexpressed in Serum (31.7), Placenta (9.2), Urinary Bladder (8.0), and Rectum (6.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TFE3 Gene
NURSA nuclear receptor signaling pathways regulating expression of TFE3 Gene:
TFE3SOURCE GeneReport for Unigene cluster for TFE3 Gene:
Hs.730740mRNA Expression by UniProt/SwissProt for TFE3 Gene:
P19532-TFE3_HUMAN
Tissue specificity:
Ubiquitous in fetal and adult tissues.
Evidence on tissue expression from TISSUES for TFE3 Gene
- Nervous system(4.6)
- Blood(4.3)
- Liver(4.3)
- Lung(2.9)
- Kidney(2.7)
- Muscle(2.3)
- Lymph node(2.1)
- Skin(2.1)
Phenotype-based relationships between genes and organs from Gene ORGANizer for TFE3 Gene
Germ Layers:
- endoderm
- mesoderm
Systems:
- respiratory
- urinary
Organs:
Thorax:
- lung
Abdomen:
- kidney
Primer Products
-
OriGene qPCR primer pairs and template standards for TFE3
-
OriGene qPCR primer pairs for TFE3
Orthologs for TFE3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | TFE3 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | TFE3 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | TFE3 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Tfe3 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Tfe3 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | TFE3 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | TFE3 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | TFE3 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | tfe3b 34 35 |
|
||
| tfe3a 34 35 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | Mitf 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | hlh-30 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for TFE3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for TFE3 Gene
Variants for TFE3 Gene
| SNP ID | Clin | Chr 0X pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000946234 | -- | 49,037,653(+) | GAGAC(C/T)GCGCC | intron-variant | |
| rs1001456832 | -- | 49,045,507(+) | GACCA(G/T)CCTGG | upstream-variant-2KB | |
| rs1002431841 | -- | 49,028,971(+) | CAGTA(C/T)GCGGA | utr-variant-3-prime | |
| rs1002846987 | -- | 49,040,741(+) | TCCTT(C/T)CCCCA | intron-variant | |
| rs1002878408 | -- | 49,041,177(+) | CCGCT(C/T)GCCTC | intron-variant |
Residual Variation Intolerance Score:
50.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.25;
25.07% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for TFE3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TFE3
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TFE3 Gene
Disorders for TFE3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| renal cell carcinoma, papillary |
|
|
| alveolar soft-part sarcoma |
|
|
| epithelioid hemangioendothelioma |
|
|
| waardenburg syndrome, type 2a |
|
|
| renal cell carcinoma |
|
Search TFE3 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
TFE3_HUMAN- Note=A chromosomal aberration involving TFE3 is found in patients with alveolar soft part sarcoma. Translocation t(X;17)(p11;q25) with ASPSCR1 forms a ASPSCR1-TFE3 fusion protein. {ECO:0000269 PubMed:11358836}.
- Note=Chromosomal aberrations involving TFE3 are found in patients with papillary renal cell carcinoma. Translocation t(X;1)(p11.2;q21.2) with PRCC; translocation t(X;1)(p11.2;p34) with PSF; inversion inv(X)(p11.2;q12) that fuses NONO to TFE3. {ECO:0000269 PubMed:8872474, ECO:0000269 PubMed:8986805}.
Relevant External Links for TFE3
No data available for Genatlas for TFE3 Gene
Publications for TFE3 Gene
- The der(17)t(X;17)(p11;q25) of human alveolar soft part sarcoma fuses the TFE3 transcription factor gene to ASPL, a novel gene at 17q25. (PMID: 11244503) Ladanyi M. … Bridge J. (Oncogene 2001) 3 4 22 64
- Fusion of a novel gene, RCC17, to the TFE3 gene in t(X;17)(p11.2;q25.3)-bearing papillary renal cell carcinomas. (PMID: 11358836) Heimann P. … Vassart G. (Cancer Res. 2001) 3 4 22 64
- Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma. (PMID: 9393982) Clark J. … Cooper C.S. (Oncogene 1997) 3 4 22 64
- The t(X;1)(p11.2;q21.2) translocation in papillary renal cell carcinoma fuses a novel gene PRCC to the TFE3 transcription factor gene. (PMID: 8872474) Sidhar S.K. … Cooper C.S. (Hum. Mol. Genet. 1996) 3 4 22 64
- The gene encoding human TFE3, a transcription factor that binds the immunoglobulin heavy-chain enhancer, maps to Xp11.22. (PMID: 1685140) Henthorn P.S. … Puck J.M. (Genomics 1991) 2 3 22 64
Products for TFE3 Gene
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for TFE3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus Biologicals
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer
- (156) abm
- (157) CrownBio