Aliases for SYP Gene
External Ids for SYP Gene
This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). [provided by RefSeq, Aug 2011]
GeneCards Summary for SYP Gene
SYP (Synaptophysin) is a Protein Coding gene. Diseases associated with SYP include pineal parenchymal tumor of intermediate differentiation and neuroendocrine carcinoma of the cervix. Among its related pathways are Neuroscience and Synaptic vesicle cycle. GO annotations related to this gene include calcium ion binding and transporter activity. An important paralog of this gene is SYNPR.
UniProtKB/Swiss-Prot for SYP Gene
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).