External Ids for STX3 Gene
Previous Symbols for STX3 Gene
The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
GeneCards Summary for STX3 Gene
STX3 (Syntaxin 3) is a Protein Coding gene. Diseases associated with STX3 include microvillus inclusion disease. Among its related pathways are Disease and Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include SNAP receptor activity and arachidonic acid binding. An important paralog of this gene is STX4.
UniProtKB/Swiss-Prot for STX3 Gene
Potentially involved in docking of synaptic vesicles at presynaptic active zones