Aliases for SOX12 Gene
External Ids for SOX12 Gene
Previous Symbols for SOX12 Gene
Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types. [provided by RefSeq, Jan 2013]
GeneCards Summary for SOX12 Gene
SOX12 (SRY (Sex Determining Region Y)-Box 12) is a Protein Coding gene. Among its related pathways are ERK Signaling. GO annotations related to this gene include RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and RNA polymerase II transcription coactivator activity. An important paralog of this gene is SOX3.
UniProtKB/Swiss-Prot for SOX12 Gene
Binds to the sequence 5-AACAAT-3.