Free for academic non-profit institutions. Other users need a Commercial license

Aliases for JMJD4 Gene

Aliases for JMJD4 Gene

  • Jumonji Domain Containing 4 2 3
  • 2-Oxoglutarate- And Fe(II)-Dependent Oxygenase 2
  • Jumonji Domain-Containing Protein 4 4
  • C4 Lysyl Hydroxylase 2

External Ids for JMJD4 Gene

Summaries for JMJD4 Gene

GeneCards Summary for JMJD4 Gene

JMJD4 (Jumonji Domain Containing 4) is a Protein Coding gene. An important paralog of this gene is JMJD6.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for JMJD4 Gene

Genomics for JMJD4 Gene

Genomic Location for JMJD4 Gene

Start:
227,730,425 bp from pter
End:
227,735,411 bp from pter
Size:
4,987 bases
Orientation:
Minus strand

Genomic View for JMJD4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for JMJD4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for JMJD4 Gene

Regulatory Elements for JMJD4 Gene

Proteins for JMJD4 Gene

  • Protein details for JMJD4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H9V9-JMJD4_HUMAN
    Recommended name:
    JmjC domain-containing protein 4
    Protein Accession:
    Q9H9V9
    Secondary Accessions:
    • Q5TBZ1
    • Q5TBZ6
    • Q9H970

    Protein attributes for JMJD4 Gene

    Size:
    463 amino acids
    Molecular mass:
    52493 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14366.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI23067.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for JMJD4 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for JMJD4 Gene

Proteomics data for JMJD4 Gene at MOPED

Post-translational modifications for JMJD4 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys153 and Lys447

Other Protein References for JMJD4 Gene

No data available for DME Specific Peptides for JMJD4 Gene

Domains for JMJD4 Gene

Protein Domains for JMJD4 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

JMJD4_HUMAN
Domain:
  • Contains 1 JmjC domain.:
    • Q9H9V9
genes like me logo Genes that share domains with JMJD4: view

No data available for Gene Families for JMJD4 Gene

Function for JMJD4 Gene

Gene Ontology (GO) - Molecular Function for JMJD4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 24360279
genes like me logo Genes that share ontologies with JMJD4: view

miRNA for JMJD4 Gene

miRTarBase miRNAs that target JMJD4

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for JMJD4 Gene

Localization for JMJD4 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for JMJD4 Gene COMPARTMENTS Subcellular localization image for JMJD4 gene
Compartment Confidence
mitochondrion 2
cytosol 1
extracellular 1
peroxisome 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for JMJD4 Gene

Pathways for JMJD4 Gene

SuperPathways for JMJD4 Gene

No Data Available

Interacting Proteins for JMJD4 Gene

Gene Ontology (GO) - Biological Process for JMJD4 Gene

None

No data available for Pathways by source for JMJD4 Gene

Transcripts for JMJD4 Gene

Unigene Clusters for JMJD4 Gene

Jumonji domain containing 4:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for JMJD4 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c
SP1: -
SP2: - -
SP3:
SP4:

Relevant External Links for JMJD4 Gene

GeneLoc Exon Structure for
JMJD4
ECgene alternative splicing isoforms for
JMJD4

Expression for JMJD4 Gene

mRNA expression in normal human tissues for JMJD4 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for JMJD4 Gene

SOURCE GeneReport for Unigene cluster for JMJD4 Gene Hs.555974

genes like me logo Genes that share expressions with JMJD4: view

Orthologs for JMJD4 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for JMJD4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia JMJD4 36
  • 99.28 (n)
  • 98.92 (a)
JMJD4 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia JMJD4 36
  • 79.33 (n)
  • 76.92 (a)
JMJD4 37
  • 75 (a)
OneToOne
dog
(Canis familiaris)
Mammalia JMJD4 36
  • 78.65 (n)
  • 78.26 (a)
JMJD4 37
  • 78 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Jmjd4 36
  • 78.21 (n)
  • 76.44 (a)
Jmjd4 16
Jmjd4 37
  • 74 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia JMJD4 37
  • 58 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Jmjd4 36
  • 79.01 (n)
  • 77.88 (a)
chicken
(Gallus gallus)
Aves JMJD4 36
  • 64.81 (n)
  • 60.77 (a)
JMJD4 37
  • 59 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia JMJD4 37
  • 58 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia jmjd4 36
  • 62 (n)
  • 57.77 (a)
zebrafish
(Danio rerio)
Actinopterygii jmjd4 36
  • 61.1 (n)
  • 57.41 (a)
jmjd4 37
  • 52 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP008415 36
  • 53.66 (n)
  • 40.46 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG7200 36
  • 50.38 (n)
  • 39.94 (a)
CG7200 37
  • 33 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea jmjd-4 37
  • 30 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G63080 36
  • 46.49 (n)
  • 37.65 (a)
rice
(Oryza sativa)
Liliopsida Os01g0546900 36
  • 48.14 (n)
  • 38.31 (a)
Species with no ortholog for JMJD4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for JMJD4 Gene

ENSEMBL:
Gene Tree for JMJD4 (if available)
TreeFam:
Gene Tree for JMJD4 (if available)

Paralogs for JMJD4 Gene

Paralogs for JMJD4 Gene

Pseudogenes.org Pseudogenes for JMJD4 Gene

genes like me logo Genes that share paralogs with JMJD4: view

Variants for JMJD4 Gene

Sequence variations from dbSNP and Humsavar for JMJD4 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
VAR_032898 -
VAR_032899 -
VAR_032900 -
VAR_032901 -

Structural Variations from Database of Genomic Variants (DGV) for JMJD4 Gene

Variant ID Type Subtype PubMed ID
esv32853 CNV Gain 17666407
nsv826908 CNV Gain 20364138
nsv515496 CNV Loss 19592680
nsv873249 CNV Loss 21882294

Relevant External Links for JMJD4 Gene

HapMap Linkage Disequilibrium report
JMJD4

Disorders for JMJD4 Gene

No disorders were found for JMJD4 Gene.

No data available for UniProtKB/Swiss-Prot for JMJD4 Gene

Publications for JMJD4 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Optimal translational termination requires C4 lysyl hydroxylation of eRF1. (PMID: 24486019) Feng T. … Coleman M.L. (Mol. Cell 2014) 2 3
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Hundreds of variants clustered in genomic loci and biological pathways affect human height. (PMID: 20881960) Lango Allen H. … Hirschhorn J.N. (Nature 2010) 3

Products for JMJD4 Gene

Sources for JMJD4 Gene

Back to Top

Content