Aliases for RTN4R Gene
External Ids for RTN4R Gene
Previous GeneCards Identifiers for RTN4R Gene
This gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. [provided by RefSeq, Jul 2008]
GeneCards Summary for RTN4R Gene
RTN4R (Reticulon 4 Receptor) is a Protein Coding gene. Diseases associated with RTN4R include schizophrenia and spinal cord injury. Among its related pathways are Guidance Cues and Growth Cone Motility and NgR-p75(NTR)-Mediated Signaling. GO annotations related to this gene include receptor activity. An important paralog of this gene is TPBGL.
UniProtKB/Swiss-Prot for RTN4R Gene
Receptor for RTN4, OMG and MAG. Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Acts in conjunction with RTN4 and LINGO1 in regulating neuronal precursor cell motility during cortical development.