Aliases for MRPL1 Gene
External Ids for MRPL1 Gene
Previous GeneCards Identifiers for MRPL1 Gene
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family. [provided by RefSeq, Jul 2008]
GeneCards Summary for MRPL1 Gene
MRPL1 (Mitochondrial Ribosomal Protein L1) is a Protein Coding gene. Among its related pathways are CFTR translational fidelity (class I mutations). GO annotations related to this gene include RNA binding and structural constituent of ribosome.