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Aliases for SKP1 Gene

Aliases for SKP1 Gene

  • S-Phase Kinase-Associated Protein 1 2 3 5
  • Transcription Elongation Factor B Polypeptide 1-Like 3 4
  • Cyclin-A/CDK2-Associated Protein P19 3 4
  • Organ Of Corti Protein II 3 4
  • Organ Of Corti Protein 2 3 4
  • P19skp1 3 4
  • OCP-II 3 4
  • TCEB1L 3 4
  • SKP1A 3 4
  • EMC19 3 4
  • OCP-2 3 4
  • OCP2 3 4
  • SIII 3 4
  • P19A 3 4
  • RNA Polymerase II Elongation Factor-Like Protein OCP2 3
  • RNA Polymerase II Elongation Factor-Like Protein 4
  • S-Phase Kinase-Associated Protein 1A (P19A) 2
  • Cyclin A/CDK2-Associated Protein P19 3
  • Cyclin A/CDK2-Associated P19 3

External Ids for SKP1 Gene

Previous HGNC Symbols for SKP1 Gene

  • SKP1A

Previous GeneCards Identifiers for SKP1 Gene

  • GC05M133521
  • GC05M128677
  • GC05M133484

Summaries for SKP1 Gene

Entrez Gene Summary for SKP1 Gene

  • This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jul 2008]

GeneCards Summary for SKP1 Gene

SKP1 (S-Phase Kinase-Associated Protein 1) is a Protein Coding gene. Among its related pathways are Cell cycle and Circadian rhythm. GO annotations related to this gene include ubiquitin-protein transferase activity. An important paralog of this gene is ENSG00000272772.

UniProtKB/Swiss-Prot for SKP1 Gene

  • Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC) directs ubiquitination of NFKBIB, NFKBIE, ATF4, SMAD3, SMAD4, CDC25A, FBXO5, CEP68 and probably NFKB2 (PubMed:25704143). SCF(SKP2) directs ubiquitination of phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. SCF(SKP2) directs ubiquitination of ORC1, CDT1, RBL2, ELF4, CDKN1A, RAG2, FOXO1A, and probably MYC and TAL1. SCF(FBXW7) directs ubiquitination of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1. SCF(FBXW2) directs ubiquitination of GCM1. SCF(FBXO32) directs ubiquitination of MYOD1. SCF(FBXO7) directs ubiquitination of BIRC2 and DLGAP5. SCF(FBXO33) directs ubiquitination of YBX1. SCF(FBXO11) directs ubiquitination of BCL6 and DTL but does not seem to direct ubiquitination of TP53. SCF(BTRC) mediates the ubiquitination of NFKBIA at Lys-21 and Lys-22; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(CCNF) directs ubiquitination of CCP110. SCF(FBXL3) and SCF(FBXL21) direct ubiquitination of CRY1 and CRY2. SCF(FBXO9) directs ubiquitination of TTI1 and TELO2. SCF(FBXO10) directs ubiquitination of BCL2.

Gene Wiki entry for SKP1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SKP1 Gene

Genomics for SKP1 Gene

Regulatory Elements for SKP1 Gene

Enhancers for SKP1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SKP1 on UCSC Golden Path with GeneCards custom track

Promoters for SKP1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SKP1 on UCSC Golden Path with GeneCards custom track

Genomic Location for SKP1 Gene

Chromosome:
5
Start:
134,148,935 bp from pter
End:
134,177,038 bp from pter
Size:
28,104 bases
Orientation:
Minus strand

Genomic View for SKP1 Gene

Genes around SKP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SKP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SKP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SKP1 Gene

Proteins for SKP1 Gene

  • Protein details for SKP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P63208-SKP1_HUMAN
    Recommended name:
    S-phase kinase-associated protein 1
    Protein Accession:
    P63208
    Secondary Accessions:
    • D3DQ97
    • D3DQ98
    • P34991
    • Q8TAY2

    Protein attributes for SKP1 Gene

    Size:
    163 amino acids
    Molecular mass:
    18658 Da
    Quaternary structure:
    • Component of multiple SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes formed of CUL1, SKP1, RBX1 and a variable F-box domain-containing protein as substrate-specific subunit. Component of the SCF(FBXW11) complex containing FBXW11. Component of the SCF(SKP2) complex containing SKP2, in which it interacts directly with SKP1, SKP2 and RBX1. Component of the SCF(FBXW2) complex containing FBXw2. Component of the SCF(FBXO32) complex containing FBXO32. Component of the probable SCF(FBXO7) complex containing FBXO7. Component of the SCF(FBXO10) complex containing FBXO10. Component of the SCF(FBXO11) complex containing FBXO11. Component of the SCF(FBXO25) complex containing FBXO25. Component of the SCF(FBXO33) complex containing FBXO33. Component of the probable SCF(FBXO4) complex containing FBXO4. Component of the SCF(FBXO44) complex, composed of SKP1, CUL1 and FBXO44. Component of the SCF(BTRC) complex, composed of SKP1, CUL1 and BTRC. This complex binds phosphorylated NFKBIA. Part of a SCF complex consisting of CUL1, RBX1, SKP1 and FBXO2. Component of a SCF(SKP2)-like complex containing CUL1, SKP1, TRIM21 and SKP2. Component of the SCF(FBXO17) complex, composed of SKP1, CUL1 and FBXO17. Component of the SCF(FBXO27) complex, composed of SKP1, CUL1 and FBXO27. Component of the SCF(CCNF) complex consisting of CUL1, RBX1, SKP1 and CCNF. Component of the SCF(FBXL3) complex composed of CUL1, SKP1, RBX1 and FBXL3. Component of the SCF(FBXL21) complex composed of CUL1, SKP1, RBX1 and FBXL21. Component of the SCF(FBXO9) composed of CUL1, SKP1, RBX1 and FBXO9. Component of the SCF(FBXW7) composed of CUL1, SKP1, RBX1 and FBXW7. Interacts with CEP68 (PubMed:25503564).

    Three dimensional structures from OCA and Proteopedia for SKP1 Gene

    Alternative splice isoforms for SKP1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SKP1 Gene

Proteomics data for SKP1 Gene at MOPED

Post-translational modifications for SKP1 Gene

  • Ubiquitination at Lys 121, Lys 137, Lys 142, and Lys 155
  • Modification sites at PhosphoSitePlus

Antibody Products

  • Cell Signaling Technology (CST) Antibodies for SKP1 (SKP1A)

No data available for DME Specific Peptides for SKP1 Gene

Domains & Families for SKP1 Gene

Gene Families for SKP1 Gene

Protein Domains for SKP1 Gene

Suggested Antigen Peptide Sequences for SKP1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P63208

UniProtKB/Swiss-Prot:

SKP1_HUMAN :
  • Belongs to the SKP1 family.
Family:
  • Belongs to the SKP1 family.
genes like me logo Genes that share domains with SKP1: view

Function for SKP1 Gene

Molecular function for SKP1 Gene

UniProtKB/Swiss-Prot Function:
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC) directs ubiquitination of NFKBIB, NFKBIE, ATF4, SMAD3, SMAD4, CDC25A, FBXO5, CEP68 and probably NFKB2 (PubMed:25704143). SCF(SKP2) directs ubiquitination of phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. SCF(SKP2) directs ubiquitination of ORC1, CDT1, RBL2, ELF4, CDKN1A, RAG2, FOXO1A, and probably MYC and TAL1. SCF(FBXW7) directs ubiquitination of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1. SCF(FBXW2) directs ubiquitination of GCM1. SCF(FBXO32) directs ubiquitination of MYOD1. SCF(FBXO7) directs ubiquitination of BIRC2 and DLGAP5. SCF(FBXO33) directs ubiquitination of YBX1. SCF(FBXO11) directs ubiquitination of BCL6 and DTL but does not seem to direct ubiquitination of TP53. SCF(BTRC) mediates the ubiquitination of NFKBIA at Lys-21 and Lys-22; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(CCNF) directs ubiquitination of CCP110. SCF(FBXL3) and SCF(FBXL21) direct ubiquitination of CRY1 and CRY2. SCF(FBXO9) directs ubiquitination of TTI1 and TELO2. SCF(FBXO10) directs ubiquitination of BCL2.

Gene Ontology (GO) - Molecular Function for SKP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004842 ubiquitin-protein transferase activity IDA,TAS --
GO:0005515 protein binding IPI 11099048
genes like me logo Genes that share ontologies with SKP1: view
genes like me logo Genes that share phenotypes with SKP1: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SKP1 Gene

Localization for SKP1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SKP1 Gene COMPARTMENTS Subcellular localization image for SKP1 gene
Compartment Confidence
cytosol 5
extracellular 5
nucleus 5
cytoskeleton 2
endoplasmic reticulum 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for SKP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA 18929646
GO:0070062 extracellular exosome IDA 23376485
genes like me logo Genes that share ontologies with SKP1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for SKP1 Gene

Pathways & Interactions for SKP1 Gene

SuperPathways for SKP1 Gene

Superpath Contained pathways
1 MyD88 cascade initiated on plasma membrane
2 CDK-mediated phosphorylation and removal of Cdc6
.78
3 Signaling by NOTCH1
4 Interleukin-3, 5 and GM-CSF signaling
5 Infectious disease
.48
genes like me logo Genes that share pathways with SKP1: view

UniProtKB/Swiss-Prot P63208-SKP1_HUMAN

  • Pathway: Protein modification; protein ubiquitination.

SIGNOR curated interactions for SKP1 Gene

Activates:
Is activated by:

Gene Ontology (GO) - Biological Process for SKP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000086 G2/M transition of mitotic cell cycle TAS --
GO:0000278 mitotic cell cycle TAS --
GO:0002223 stimulatory C-type lectin receptor signaling pathway TAS --
GO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS --
GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS --
genes like me logo Genes that share ontologies with SKP1: view

Drugs & Compounds for SKP1 Gene

(6) Drugs for SKP1 Gene - From: DrugBank and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
(2S)-2-(1H-indol-3-yl)hexanoic acid Experimental Pharma Target 0
(2S)-2-(1H-indol-3-yl)pentanoic acid Experimental Pharma Target 0
(2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid Experimental Pharma Target 0
1-Naphthaleneacetic acid Experimental Pharma Target 0
Indoleacetic acid Experimental Pharma Target 0
genes like me logo Genes that share compounds with SKP1: view

Transcripts for SKP1 Gene

Unigene Clusters for SKP1 Gene

S-phase kinase-associated protein 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SKP1 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7
SP1: - - - -
SP2: - - -
SP3: - -
SP4: -
SP5: - -

Relevant External Links for SKP1 Gene

GeneLoc Exon Structure for
SKP1
ECgene alternative splicing isoforms for
SKP1

Expression for SKP1 Gene

mRNA expression in normal human tissues for SKP1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for SKP1 Gene

This gene is overexpressed in Brain (19.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for SKP1 Gene



SOURCE GeneReport for Unigene cluster for SKP1 Gene Hs.171626

genes like me logo Genes that share expression patterns with SKP1: view

Protein tissue co-expression partners for SKP1 Gene

- Elite partner

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SKP1 Gene

Orthologs for SKP1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for SKP1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SKP1 35
  • 92.84 (n)
  • 100 (a)
-- 36
  • 98 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia SKP1 35
  • 97.14 (n)
  • 100 (a)
SKP1 36
  • 99 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Skp1a 35
  • 94.48 (n)
  • 99.39 (a)
Skp1a 16
Skp1a 36
  • 99 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia SKP1 35
  • 100 (n)
  • 100 (a)
-- 36
  • 94 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Skp1 35
  • 94.48 (n)
  • 99.39 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 83 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 95 (a)
OneToMany
chicken
(Gallus gallus)
Aves SKP1 35
  • 88.55 (n)
  • 100 (a)
SKP1 36
  • 100 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 100 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia skp1 35
  • 84.25 (n)
  • 100 (a)
African clawed frog
(Xenopus laevis)
Amphibia skp1a-prov 35
zebrafish
(Danio rerio)
Actinopterygii skp1 35
  • 84.05 (n)
  • 98.77 (a)
zgc73186 35
skp1 36
  • 99 (a)
OneToMany
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.11291 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP008719 35
  • 70.16 (n)
  • 84.57 (a)
fruit fly
(Drosophila melanogaster)
Insecta skpA 35
  • 69.96 (n)
  • 77.16 (a)
skpA 36
  • 77 (a)
ManyToMany
skpB 36
  • 69 (a)
ManyToMany
skpC 36
  • 54 (a)
ManyToMany
skpD 36
  • 51 (a)
ManyToMany
skpE 36
  • 44 (a)
ManyToMany
skpF 36
  • 54 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea skr-1 35
  • 65.2 (n)
  • 71.7 (a)
skr-1 36
  • 65 (a)
ManyToMany
skr-10 36
  • 35 (a)
ManyToMany
skr-12 36
  • 38 (a)
ManyToMany
skr-13 36
  • 38 (a)
ManyToMany
skr-14 36
  • 32 (a)
ManyToMany
skr-15 36
  • 29 (a)
ManyToMany
skr-16 36
  • 29 (a)
ManyToMany
skr-17 36
  • 33 (a)
ManyToMany
skr-18 36
  • 30 (a)
ManyToMany
skr-19 36
  • 34 (a)
ManyToMany
skr-2 36
  • 56 (a)
ManyToMany
skr-20 36
  • 30 (a)
ManyToMany
skr-21 36
  • 25 (a)
ManyToMany
skr-3 36
  • 54 (a)
ManyToMany
skr-4 36
  • 52 (a)
ManyToMany
skr-5 36
  • 53 (a)
ManyToMany
skr-6 36
  • 45 (a)
ManyToMany
skr-7 36
  • 35 (a)
ManyToMany
skr-8 36
  • 35 (a)
ManyToMany
skr-9 36
  • 34 (a)
ManyToMany
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ADR295C 35
  • 53.75 (n)
  • 51.87 (a)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0E16941g 35
  • 61.6 (n)
  • 58.23 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SKP1 35
  • 59.49 (n)
  • 56.96 (a)
SKP1 36
  • 42 (a)
OneToMany
SKP1 38
rice
(Oryza sativa)
Liliopsida Os11g0456300 35
  • 62.34 (n)
  • 59.09 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.3812 35
bread mold
(Neurospora crassa)
Ascomycetes NCU08991 35
  • 64.36 (n)
  • 59.75 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes skp1 35
  • 57.02 (n)
  • 58.49 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.11317 36
  • 90 (a)
OneToMany
Species with no ortholog for SKP1:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SKP1 Gene

ENSEMBL:
Gene Tree for SKP1 (if available)
TreeFam:
Gene Tree for SKP1 (if available)

Paralogs for SKP1 Gene

Paralogs for SKP1 Gene

genes like me logo Genes that share paralogs with SKP1: view

Variants for SKP1 Gene

Sequence variations from dbSNP and Humsavar for SKP1 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
VAR_051999 -
rs1181319 -- 134,160,326(+) cacca(A/C)agcct intron-variant
rs6596167 -- 134,161,558(+) GCAAA(A/G)CTAAC intron-variant
rs3053002 -- 134,161,490(+) TTAAT(-/GAT)ATGTA intron-variant
rs6859052 -- 134,173,408(+) actga(C/T)tgagc intron-variant

Variation tolerance for SKP1 Gene

Residual Variation Intolerance Score: 44.4% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SKP1 Gene

HapMap Linkage Disequilibrium report
SKP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SKP1 Gene

Disorders for SKP1 Gene

Relevant External Links for SKP1

Genetic Association Database (GAD)
SKP1
Human Genome Epidemiology (HuGE) Navigator
SKP1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SKP1

No disorders were found for SKP1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SKP1 Gene

Publications for SKP1 Gene

  1. p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase. (PMID: 7553852) Zhang H. … Beach D. (Cell 1995) 2 3 4 67
  2. Chromosomal mapping of the genes for the human CDK2/cyclin A-associated proteins p19 (SKP1A and SKP1B) and p45 (SKP2). (PMID: 8646875) Demetrick D.J. … Beach D.H. (Cytogenet. Cell Genet. 1996) 2 3 23
  3. Phosphorylation of Ser72 is dispensable for Skp2 assembly into an active SCF ubiquitin ligase and its subcellular localization. (PMID: 20160477) Bashir T. … Pagano M. (Cell Cycle 2010) 3 23
  4. Array MAPPIT: high-throughput interactome analysis in mammalian cells. (PMID: 19159283) Lievens S. … Tavernier J. (J. Proteome Res. 2009) 3 23
  5. Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB. (PMID: 19270694) Lin H.K. … Pandolfi P.P. (Nat. Cell Biol. 2009) 3 23

Products for SKP1 Gene

Sources for SKP1 Gene

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