Aliases for CRTC3 Gene
Aliases for CRTC3 Gene
- CREB Regulated Transcription Coactivator 3 2 3 5
- TORC-3 3 4
- TORC3 3 4
- Transducer Of Regulated CAMP Response Element-Binding Protein (CREB) 3 3
- Transducer Of Regulated CAMP Response Element-Binding Protein 3 4
- CREB-Regulated Transcription Coactivator 3 3
- Transducer Of Regulated CREB Protein 3 3
- Transducer Of CREB Protein 3 4
External Ids for CRTC3 Gene
- HGNC: 26148
- Entrez Gene: 64784
- Ensembl: ENSG00000140577
- OMIM: 608986
- UniProtKB: Q6UUV7
Previous GeneCards Identifiers for CRTC3 Gene
- GC15P088875
- GC15P091073
- GC15P067184
Summaries for CRTC3 Gene
-
This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
GeneCards Summary for CRTC3 Gene
CRTC3 (CREB Regulated Transcription Coactivator 3) is a Protein Coding gene. Diseases associated with CRTC3 include Human T-Cell Leukemia Virus Type 1 and Mucoepidermoid Carcinoma. Among its related pathways are Mitochondrial Gene Expression and HTLV-I infection. GO annotations related to this gene include cAMP response element binding protein binding. An important paralog of this gene is CRTC2.
UniProtKB/Swiss-Prot for CRTC3 Gene
-
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 Ser-133 phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CRTC3 Gene
Genomics for CRTC3 Gene
Regulatory Elements for CRTC3 Gene
Enhancers for CRTC3 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CRTC3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for CRTC3 Gene
- Chromosome:
- 15
- Start:
- 90,529,886 bp from pter
- End:
- 90,645,345 bp from pter
- Size:
- 115,460 bases
- Orientation:
- Plus strand
Genomic View for CRTC3 Gene
Genes around CRTC3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 15q26.1 by Ensembl
- 15q26.1 by Entrez Gene
- 15q26.1 by HGNC
CRTC3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CRTC3 Gene
Proteins for CRTC3 Gene
-
Protein details for CRTC3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6UUV7-CRTC3_HUMAN
- Recommended name:
- CREB-regulated transcription coactivator 3
- Protein Accession:
- Q6UUV7
- Q6DK61
- Q6DK62
- Q8NF38
- Q9H6U2
Protein attributes for CRTC3 Gene
- Size:
- 619 amino acids
- Molecular mass:
- 66959 Da
- Quaternary structure:
-
- Binding, as a tetramer, through its N-terminal region, with the bZIP domain of CREB1 enhances recruitment of TAF4 to the promoter. Arg-314 in the bZIP domain of CREB1 is essential for this interaction (By similarity). Interaction with HTLV-1 TAX enhances its transcriptional activity. Interacts, via the N-terminal with the ankyrin repeats of BCL3, to form a complex with CREB1 on CRE and TxRE responsive elements and represses HTLV-1 LTR-mediated transcription.
- SequenceCaution:
-
- Sequence=BAC03424.1; Type=Frameshift; Positions=82; Evidence={ECO:0000305};
Protein Expression for CRTC3 Gene
Post-translational modifications for CRTC3 Gene
Other Protein References for CRTC3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for CRTC3 (TORC3)
- Cell Signaling Technology (CST) Antibodies for CRTC3 (TORC3)
-
Custom Antibody ServicesOriGene Antibodies for CRTC3
- Novus Biologicals Antibodies for CRTC3
-
Cloud-Clone Corp. Antibodies for CRTC3
- Invitrogen Antibodies for CRTC3
- antibodies-online Antibodies for CRTC3: See all 25
- GeneTex CRTC3 antibody for CRTC3
- GeneTex C10orf12 antibody for CRTC3
-
Santa Cruz Biotechnology (SCBT) Antibodies for CRTC3
Protein Products
-
OriGene Purified Proteins for CRTC3
- Search Origene for MassSpec and Protein Over-expression Lysates for CRTC3
- Origene Custom Protein Services for CRTC3
- Novus Biologicals proteins for CRTC3
-
Cloud-Clone Corp. Proteins for CRTC3
- antibodies-online Proteins for CRTC3: See all 3
- Search antibodies-online for peptides
- Search GeneTex for Proteins for CRTC3
No data available for DME Specific Peptides for CRTC3 Gene
Domains & Families for CRTC3 Gene
Suggested Antigen Peptide Sequences for CRTC3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q6UUV7- Family:
-
- Belongs to the TORC family.
No data available for Gene Families for CRTC3 Gene
Function for CRTC3 Gene
Molecular function for CRTC3 Gene
- UniProtKB/Swiss-Prot Function:
- Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 Ser-133 phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008140 | cAMP response element binding protein binding | IBA | -- |
Phenotypes for CRTC3 Gene
- MGI mutant phenotypes for CRTC3:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for CRTC3:
-
- Increased vaccinia virus (VACV) infection
- Decreased viability
- Decreased hepcidin::fluc mRNA expression
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased ionizing radiation sensitivity
- Decreased viability ratio
- Decreased p24 protein expression
- Strongly decreased CFP-tsO45G cell surface transport
- Increased G1 DNA content
- Decreased infection with West Nile virus (WNV)
- Decreased West Nile virus (WNV) infection
- Weakly decreased NFAT1-GFP nuclear translocation
- Decreased Dengue Infection
- Increased Sindbis virus (SINV) infection
- Increased cell size
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CRTC3
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CRTC3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CRTC3 gene
- Search ViGene Biosciences for CRTC3
CRISPR Products
-
OriGene CRISPR knockouts for CRTC3
-
Santa Cruz Biotechnology (SCBT) CRISPR for CRTC3
- GenScript: Design CRISPR guide RNA sequences for CRTC3
miRNA for CRTC3 Gene
- miRTarBase miRNAs that target CRTC3
-
- hsa-mir-124-3p (MIRT023199)
- hsa-mir-7-5p (MIRT025919)
- hsa-mir-671-5p (MIRT039296)
- hsa-mir-92a-3p (MIRT049715)
- hsa-mir-20a-5p (MIRT440873)
- hsa-mir-106b-5p (MIRT440874)
- hsa-mir-514b-3p (MIRT691007)
- hsa-mir-514a-3p (MIRT691008)
- hsa-mir-29b-2-5p (MIRT691009)
- hsa-mir-6079 (MIRT691010)
- hsa-mir-6828-5p (MIRT691011)
- hsa-mir-4772-5p (MIRT691012)
- hsa-mir-4487 (MIRT691013)
- hsa-mir-642b-3p (MIRT691014)
- hsa-mir-642a-3p (MIRT691015)
- hsa-mir-29b-1-5p (MIRT691016)
- hsa-mir-4748 (MIRT691017)
- hsa-mir-4464 (MIRT691018)
- hsa-mir-708-5p (MIRT691019)
- hsa-mir-3139 (MIRT691020)
- hsa-mir-28-5p (MIRT691021)
- hsa-mir-129-2-3p (MIRT691022)
- hsa-mir-129-1-3p (MIRT691023)
- hsa-mir-383-5p (MIRT691024)
- hsa-mir-6768-5p (MIRT691025)
- hsa-mir-93-5p (MIRT727925)
- hsa-mir-519d-3p (MIRT727926)
- hsa-mir-20b-5p (MIRT727927)
- hsa-mir-17-5p (MIRT727928)
miRNA Products
- Search ViGene Biosciences for CRTC3
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for CRTC3
- Browse OriGene Inhibitory RNA Products For CRTC3
-
ViGene Biosciences ready-to-package AAV shRNAs for CRTC3 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for CRTC3
- VectorBuilder custom plasmid, inducible vectors for CRTC3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CRTC3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CRTC3
-
ViGene Biosciences adenoviral particle packaged cDNA for CRTC3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CRTC3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CRTC3 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CRTC3 Gene
Localization for CRTC3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CRTC3 Gene
- Nucleus. Cytoplasm. Note=Appears to be mainly nuclear. {ECO:0000269 PubMed:15454081}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | -- |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005737 | cytoplasm | IEA,IBA | -- |
| GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for CRTC3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Mitochondrial Gene Expression | ||
| 2 | HTLV-I infection | ||
| 3 | Glucose / Energy Metabolism | ||
| 4 | BMAL1-CLOCK,NPAS2 activates circadian gene expression |
.68
|
|
| 5 | Organelle biogenesis and maintenance | ||
Pathways by source for CRTC3 Gene
1 Cell Signaling Technology pathway for CRTC3 Gene
4 Reactome pathways for CRTC3 Gene
1 KEGG pathway for CRTC3 Gene
Interacting Proteins for CRTC3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0016032 | viral process | IEA | -- |
| GO:0032793 | positive regulation of CREB transcription factor activity | IBA,IEA | -- |
| GO:0042116 | macrophage activation | IMP | 23033494 |
Drugs & Compounds for CRTC3 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| cyclic amp | Experimental | Pharma | 0 |
Transcripts for CRTC3 Gene
mRNA/cDNA for CRTC3 Gene
- (4) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (125) Selected AceView cDNA sequences:
- (14) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CRTC3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CRTC3
-
Santa Cruz Biotechnology (SCBT) CRISPR for CRTC3
- GenScript: Design CRISPR guide RNA sequences for CRTC3
miRNA Products
- Search ViGene Biosciences for CRTC3
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for CRTC3
- Browse OriGene Inhibitory RNA Products For CRTC3
-
ViGene Biosciences ready-to-package AAV shRNAs for CRTC3 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for CRTC3
- VectorBuilder custom plasmid, inducible vectors for CRTC3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CRTC3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 | ^ | 19a | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: |
| ExUns: | 19b |
|---|---|
| SP1: | |
| SP2: | |
| SP3: | |
| SP4: | |
| SP5: | |
| SP6: | |
| SP7: | |
| SP8: | |
| SP9: |
Expression for CRTC3 Gene
This gene is overexpressed in Testis (24.8), Placenta (11.3), and CD8 Tcells (7.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CRTC3 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CRTC3 Gene:
CRTC3SOURCE GeneReport for Unigene cluster for CRTC3 Gene:
Hs.567572mRNA Expression by UniProt/SwissProt for CRTC3 Gene:
Q6UUV7-CRTC3_HUMAN
Tissue specificity:
Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.
Evidence on tissue expression from TISSUES for CRTC3 Gene
- Nervous system(4.6)
- Spleen(4.3)
Primer Products
-
OriGene qPCR primer pairs and template standards for CRTC3
-
OriGene qPCR primer pairs for CRTC3
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for CRTC3 Gene
Orthologs for CRTC3 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CRTC3 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Crtc3 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Crtc3 34 16 35 |
|
||
| cow (Bos Taurus) |
Mammalia | CRTC3 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | CRTC3 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CRTC3 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | CRTC3 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | crtc3 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | crtc3 34 35 |
|
- Species where no ortholog for CRTC3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for CRTC3 Gene
(3) SIMAP similar genes for CRTC3 Gene using alignment to 3 proteins:
Variants for CRTC3 Gene
| SNP ID | Clin | Chr 15 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs193921108 | Uncertain significance | 90,638,566(+) | AGCCC(A/C/G/T)GCGCC | intron-variant, reference, missense | |
| rs1000027365 | -- | 90,600,560(+) | CCTGA(C/T)CCACC | intron-variant, nc-transcript-variant | |
| rs1000038445 | -- | 90,535,551(+) | TGGCT(C/G)TGAAG | intron-variant | |
| rs1000042469 | -- | 90,573,441(+) | GTGGC(C/G)TTAAT | intron-variant | |
| rs1000076197 | -- | 90,595,426(+) | AATTA(A/G)CCAGG | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1259n106 | CNV | deletion | 24896259 |
| esv1007679 | CNV | deletion | 20482838 |
| esv1236283 | CNV | deletion | 17803354 |
| esv2234796 | CNV | deletion | 18987734 |
| esv2512119 | CNV | deletion | 19546169 |
| esv2750011 | CNV | deletion | 23290073 |
| esv3217123 | CNV | deletion | 24192839 |
| esv33061 | CNV | loss | 17666407 |
| esv3552839 | CNV | deletion | 23714750 |
| esv3569875 | CNV | gain | 25503493 |
| esv3955 | CNV | loss | 18987735 |
| esv5649 | CNV | gain | 19470904 |
| esv8010 | CNV | loss | 19470904 |
| nsv1045042 | CNV | gain | 25217958 |
| nsv1069883 | CNV | deletion | 25765185 |
| nsv1078211 | CNV | insertion | 25765185 |
| nsv1127452 | CNV | deletion | 24896259 |
| nsv1142183 | CNV | tandem duplication | 24896259 |
| nsv1148246 | CNV | deletion | 26484159 |
| nsv1662 | CNV | insertion | 18451855 |
| nsv475139 | CNV | novel sequence insertion | 20440878 |
| nsv479235 | CNV | novel sequence insertion | 20440878 |
| nsv509582 | CNV | insertion | 20534489 |
| nsv570396 | CNV | gain | 21841781 |
| nsv833088 | CNV | loss | 17160897 |
| nsv94691 | CNV | deletion | 16902084 |
| nsv957961 | CNV | deletion | 24416366 |
| nsv984108 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
37.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
9.81;
89.56% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CRTC3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CRTC3
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CRTC3 Gene
Disorders for CRTC3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| human t-cell leukemia virus type 1 |
|
|
| mucoepidermoid carcinoma |
|
|
| warthin tumor |
|
|
Search CRTC3 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for CRTC3
No data available for UniProtKB/Swiss-Prot and Genatlas for CRTC3 Gene
Publications for CRTC3 Gene
- Enhanced activation of tax-dependent transcription of human T-cell leukemia virus type I (HTLV-I) long terminal repeat by TORC3. (PMID: 15466468) Koga H. … Shimotohno K. (J. Biol. Chem. 2004) 3 4 22 64
- Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells. (PMID: 14506290) Iourgenko V. … Labow M.A. (Proc. Natl. Acad. Sci. U.S.A. 2003) 2 3 4 64
- TORCs: transducers of regulated CREB activity. (PMID: 14536081) Conkright M.D. … Montminy M. (Mol. Cell 2003) 2 3 4 64
- Whole genome association scan for genetic polymorphisms influencing information processing speed. (PMID: 21130836) Luciano M. … Deary I.J. (Biol Psychol 2011) 3 46 64
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
Products for CRTC3 Gene
- R&D Systems Antibodies for CRTC3 (TORC3)
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- Novus Biologicals Antibodies for CRTC3
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- Novus Biologicals Tissue Microarrays
- Cloud-Clone Corp. Antibodies for CRTC3
- Cloud-Clone Corp. Proteins for CRTC3
- Cloud-Clone Corp Assay Kits for CRTC3
- Addgene plasmids for CRTC3
- antibodies-online Antibodies for CRTC3: See all 25
- antibodies-online Kits for CRTC3: See all 3
- antibodies-online Proteins for CRTC3: See all 3
- Search antibodies-online for peptides
- GeneTex C10orf12 antibody for CRTC3
- GeneTex CRTC3 antibody for CRTC3
- Search GeneTex for Proteins for CRTC3
- ViGene Biosciences adenoviral particle packaged cDNA for CRTC3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CRTC3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CRTC3 gene
- Search ViGene Biosciences for CRTC3
- Santa Cruz Biotechnology (SCBT) Antibodies for CRTC3
- Search Santa Cruz Biotechnology (SCBT) for CRTC3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CRTC3
- Horizon Cell Lines for CRTC3
- Cyagen custom Knockout/knockin (KOKI) mouse models for CRTC3
- VectorBuilder custom plasmid, inducible vectors for CRTC3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CRTC3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CRTC3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer