Aliases for SHOX2 Gene
Aliases for SHOX2 Gene
External Ids for SHOX2 Gene
- HGNC: 10854
- Entrez Gene: 6474
- Ensembl: ENSG00000168779
- OMIM: 602504
- UniProtKB: O60902
Previous GeneCards Identifiers for SHOX2 Gene
- GC03M154850
- GC03M158760
- GC03M159095
- GC03M159135
- GC03M159297
- GC03M157813
- GC03M155210
Summaries for SHOX2 Gene
-
This gene is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeobox genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
GeneCards Summary for SHOX2 Gene
SHOX2 (Short Stature Homeobox 2) is a Protein Coding gene. Diseases associated with SHOX2 include Turner Syndrome and Hard Palate Cancer. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is SHOX.
UniProtKB/Swiss-Prot for SHOX2 Gene
-
May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation.
Additional gene information for SHOX2 Gene
- Monarch Initiative
- Search for SHOX2 at DataMed
- Search for SHOX2 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SHOX2 Gene
Genomics for SHOX2 Gene
GeneHancer (GH) Regulatory Elements for SHOX2 Gene
Promoters and enhancers for SHOX2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around SHOX2 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for SHOX2 Gene
Genomic Locations for SHOX2 Gene
- chr3:158,095,954-158,106,503
- (GRCh38/hg38)
- Size:
- 10,550 bases
- Orientation:
- Minus strand
- chr3:157,813,800-157,824,292
- (GRCh37/hg19)
Genomic View for SHOX2 Gene
Genes around SHOX2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3q25.32 by Ensembl
- 3q25.32 by Entrez Gene
- 3q25.32 by HGNC
SHOX2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SHOX2 Gene
Proteins for SHOX2 Gene
-
Protein details for SHOX2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O60902-SHOX2_HUMAN
- Recommended name:
- Short stature homeobox protein 2
- Protein Accession:
- O60902
- O60465
- O60467
- O60903
Protein attributes for SHOX2 Gene
- Size:
- 331 amino acids
- Molecular mass:
- 34953 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAC39662.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAA05341.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAA05342.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for SHOX2 Gene
Post-translational modifications for SHOX2 Gene
No Post-translational modifications
Other Protein References for SHOX2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for SHOX2
-
Abcam antibodies for SHOX2
- Invitrogen Antibodies for SHOX2
- Search GeneTex for Antibodies for SHOX2
-
Santa Cruz Biotechnology (SCBT) Antibodies for SHOX2
Protein Products
-
OriGene Purified Proteins for SHOX2
- Search Origene for MassSpec and Protein Over-expression Lysates for SHOX2
- Origene Custom Protein Services for SHOX2
- Search GeneTex for Proteins for SHOX2
-
Abcam proteins for SHOX2
Assay Products
No data available for DME Specific Peptides for SHOX2 Gene
Domains & Families for SHOX2 Gene
Gene Families for SHOX2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for SHOX2 Gene
Suggested Antigen Peptide Sequences for SHOX2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O60902- Family:
-
- Belongs to the paired homeobox family. Bicoid subfamily.
Function for SHOX2 Gene
Molecular function for SHOX2 Gene
- GENATLAS Biochemistry:
- murine homeo box Og12X homolog,strongly expressed in developing craniofacial,brain,heart and in the mesenchym of developing limbs,highly homologous to SHOX
- UniProtKB/Swiss-Prot Function:
- May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation.
Phenotypes From GWAS Catalog for SHOX2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | -- |
| GO:0043565 | sequence-specific DNA binding | IEA | -- |
Phenotypes for SHOX2 Gene
- MGI mutant phenotypes for SHOX2:
- inferred from 9 alleles
- GenomeRNAi human phenotypes for SHOX2:
-
- Increased vaccinia virus (VACV) infection
- Negative genetic interaction between MUS81-/- and MUS81+/+
- Decreased viability ratio
- Decreased shRNA abundance (Z-score < -2)
- Resistant to vaccinia virus (VACV-A4L) infection
- Increased shRNA abundance (Z-score > 2)
- Decreased viability of wild-type and TP53 knockout cells
Animal Models for SHOX2 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for SHOX2
-
-
ViGene Biosciences lentiviral particle packaged cDNA for SHOX2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SHOX2 gene
- Search ViGene Biosciences for SHOX2
CRISPR Products
-
OriGene CRISPR knockouts for SHOX2
- genomics-online: gRNA clones - Search results for available SHOX2 gene related products
- Applied Biological Materials CRISPR for SHOX2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for SHOX2
- GenScript: Design CRISPR guide RNA sequences for SHOX2
miRNA for SHOX2 Gene
- miRTarBase miRNAs that target SHOX2
-
- hsa-mir-4668-5p (MIRT449208)
- hsa-mir-5585-3p (MIRT449209)
- hsa-mir-3613-3p (MIRT449210)
- hsa-mir-5004-5p (MIRT508453)
- hsa-mir-4470 (MIRT508454)
- hsa-mir-183-5p (MIRT508455)
- hsa-mir-8076 (MIRT508456)
- hsa-mir-5011-5p (MIRT508457)
- hsa-mir-1277-5p (MIRT508458)
- hsa-mir-190a-3p (MIRT514862)
- hsa-mir-4791 (MIRT514863)
- hsa-mir-3201 (MIRT514864)
- hsa-mir-1246 (MIRT514865)
- hsa-mir-3074-3p (MIRT514866)
- hsa-mir-6771-3p (MIRT526360)
- hsa-mir-6809-3p (MIRT617599)
- hsa-mir-6833-3p (MIRT617600)
- hsa-mir-4768-5p (MIRT617601)
- hsa-mir-511-5p (MIRT617602)
- hsa-mir-6873-3p (MIRT617603)
- hsa-mir-6881-3p (MIRT617604)
- hsa-mir-6780a-3p (MIRT617605)
- hsa-mir-7111-3p (MIRT617606)
- hsa-mir-642b-5p (MIRT617607)
- hsa-mir-6845-3p (MIRT617608)
- hsa-mir-3667-3p (MIRT617609)
- hsa-mir-877-3p (MIRT617610)
- hsa-mir-5088-3p (MIRT617611)
- hsa-mir-148a-5p (MIRT617612)
- hsa-mir-5006-3p (MIRT639165)
- hsa-mir-4755-5p (MIRT639166)
- hsa-mir-3658 (MIRT639167)
- hsa-mir-211-5p (MIRT639168)
- hsa-mir-204-5p (MIRT639169)
- hsa-mir-623 (MIRT639170)
- hsa-mir-3653-3p (MIRT639171)
- hsa-mir-1231 (MIRT736205)
- hsa-mir-1292-5p (MIRT737139)
- hsa-mir-200b-3p (MIRT738771)
- hsa-mir-200c-3p (MIRT738782)
- hsa-mir-24-1-5p (MIRT739210)
- hsa-mir-24-2-5p (MIRT739217)
- hsa-mir-3128 (MIRT740072)
- hsa-mir-3129-3p (MIRT740074)
- hsa-mir-339-3p (MIRT741363)
- hsa-mir-429 (MIRT743831)
- hsa-mir-4318 (MIRT744017)
- hsa-mir-4471 (MIRT744955)
- hsa-mir-4693-5p (MIRT747153)
- hsa-mir-4711-3p (MIRT747439)
- hsa-mir-4720-5p (MIRT747540)
- hsa-mir-4799-3p (MIRT748994)
- hsa-mir-5583-5p (MIRT750964)
- hsa-mir-5588-5p (MIRT751020)
- hsa-mir-5708 (MIRT751395)
- hsa-mir-6868-5p (MIRT757956)
- hsa-mir-8059 (MIRT760038)
- hsa-mir-8084 (MIRT760185)
- hsa-mir-892a (MIRT760448)
miRNA Products
- Search ViGene Biosciences for SHOX2
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for SHOX2
- Browse OriGene Inhibitory RNA Products For SHOX2
- genomics-online: shRNA clones - Search results for available SHOX2 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for SHOX2 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for SHOX2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SHOX2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available SHOX2 gene related products
- orf clones - Search results for available SHOX2 gene related products
- Applied Biological Materials Clones for SHOX2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for SHOX2
-
ViGene Biosciences adenoviral particle packaged cDNA for SHOX2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for SHOX2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SHOX2 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SHOX2 Gene
Localization for SHOX2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SHOX2 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| mitochondrion | 2 |
| cytosol | 2 |
| extracellular | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for SHOX2 Gene
Pathways & Interactions for SHOX2 Gene
No Data Available
Interacting Proteins for SHOX2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | IEA | -- |
| GO:0001501 | skeletal system development | TAS | 9482898 |
| GO:0001649 | osteoblast differentiation | IEA | -- |
| GO:0002053 | positive regulation of mesenchymal cell proliferation | IEA | -- |
| GO:0002062 | chondrocyte differentiation | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for SHOX2 Gene
Transcripts for SHOX2 Gene
mRNA/cDNA for SHOX2 Gene
- (8) REFSEQ mRNAs :
- (3) Additional mRNA sequences :
- (47) Selected AceView cDNA sequences:
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for SHOX2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for SHOX2
- genomics-online: gRNA clones - Search results for available SHOX2 gene related products
- Applied Biological Materials CRISPR for SHOX2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for SHOX2
- GenScript: Design CRISPR guide RNA sequences for SHOX2
miRNA Products
- Search ViGene Biosciences for SHOX2
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for SHOX2
- Browse OriGene Inhibitory RNA Products For SHOX2
- genomics-online: shRNA clones - Search results for available SHOX2 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for SHOX2 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for SHOX2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SHOX2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available SHOX2 gene related products
- orf clones - Search results for available SHOX2 gene related products
- Applied Biological Materials Clones for SHOX2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||||||
| SP3: | - | - | - | - | - | ||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||
| SP5: |
Expression for SHOX2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Bone (Muscoskeletal System)
- Chondrocytes Mandibular Condyle
- Condylar Condensation Cells Mandibular Condyle
- Glenoid Fossa Cells Mandibular Fossa
-
Hair (Integumentary System)
- Zigzag Dermal Papilla Cells Dermal Papilla
- Guard Dermal Papilla Cells Dermal Papilla
-
Dermis (Integumentary System)
- Zigzag Dermal Papilla Cells Dermal Papilla
- Guard Dermal Papilla Cells Dermal Papilla
-
Cartilage (Muscoskeletal System)
- Chondrocytes Mandibular Condyle
- Condylar Condensation Cells Mandibular Condyle
- Adipose (Muscoskeletal System)
-
Limb (Muscoskeletal System)
- Limb Muscle Progenitor Cells Forelimb Myotome
-
Skeletal Muscle (Muscoskeletal System)
- Limb Muscle Progenitor Cells Forelimb Myotome
- Neural Tube (Nervous System)
-
Heart (Cardiovascular System)
mRNA differential expression in normal tissues according to GTEx for SHOX2 Gene
This gene is overexpressed in Artery - Tibial (x7.2), Nerve - Tibial (x6.2), and Adipose - Subcutaneous (x5.1).
This gene is overexpressed in Pancreas (25.0), Platelet (17.9), and Urine (13.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for SHOX2 Gene
NURSA nuclear receptor signaling pathways regulating expression of SHOX2 Gene:
SHOX2SOURCE GeneReport for Unigene cluster for SHOX2 Gene:
Hs.55967mRNA Expression by UniProt/SwissProt for SHOX2 Gene:
O60902-SHOX2_HUMAN
Tissue specificity:
Expressed in heart, skeletal muscle, liver, lung, bone marrow fibroblast, pancreas and placenta.
Evidence on tissue expression from TISSUES for SHOX2 Gene
- Muscle(4.2)
Primer Products
-
OriGene qPCR primer pairs for SHOX2
- genomics-online: primer clones - Search results for available SHOX2 gene related products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for SHOX2 Gene
Orthologs for SHOX2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | SHOX2 33 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | SHOX2 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | SHOX2 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | SHOX2 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Shox2 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Shox2 33 16 34 |
|
||
| cow (Bos Taurus) |
Mammalia | SHOX2 33 34 |
|
||
| chicken (Gallus gallus) |
Aves | SHOX2 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | SHOX2 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | shox2 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | shox2 33 34 |
|
||
| zgc65884 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | CG34367 34 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | alr-1 34 |
|
ManyToMany |
- Species where no ortholog for SHOX2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for SHOX2 Gene
Paralogs for SHOX2 Gene
(14) SIMAP similar genes for SHOX2 Gene using alignment to 2 proteins:
Variants for SHOX2 Gene
| SNP ID | Clin | Chr 03 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs770635670 | likely-benign, not specified | 158,105,793(-) | CACCTCCTCC/CACCTCCTCCACCTCCTCC | 5_prime_UTR_variant, coding_sequence_variant, genic_upstream_transcript_variant, inframe_insertion, upstream_transcript_variant | |
| rs375389609 | uncertain-significance, not specified | 158,105,730(-) | T/A/C | 5_prime_UTR_variant, coding_sequence_variant, genic_upstream_transcript_variant, missense_variant, upstream_transcript_variant | |
| rs747236738 | uncertain-significance, not specified | 158,105,803(-) | G/A | 5_prime_UTR_variant, coding_sequence_variant, genic_upstream_transcript_variant, synonymous_variant, upstream_transcript_variant | |
| rs753047735 | uncertain-significance, not specified | 158,105,089(-) | C/T | 5_prime_UTR_variant, coding_sequence_variant, intron_variant, synonymous_variant | |
| rs1000097517 | -- | 158,106,314(-) | G/A | upstream_transcript_variant |
Residual Variation Intolerance Score:
13.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.60;
12.93% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SHOX2 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SHOX2 Gene
Disorders for SHOX2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| turner syndrome |
|
|
| hard palate cancer |
|
|
| sinoatrial node disease |
|
|
| leri-weill dyschondrosteosis |
|
|
| cornelia de lange syndrome |
|
Search SHOX2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SHOX2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for SHOX2 Gene
Publications for SHOX2 Gene
- A new human homeobox gene OGI2X is a member of the most conserved homeobox gene family and is expressed during heart development in mouse. (PMID: 9466998) Semina EV … Murray JC (Human molecular genetics 1998) 2 3 4 22 58
- SHOT, a SHOX-related homeobox gene, is implicated in craniofacial, brain, heart, and limb development. (PMID: 9482898) Blaschke RJ … Rappold GA (Proceedings of the National Academy of Sciences of the United States of America 1998) 2 3 4 22 58
- High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. (PMID: 19453261) Yerges LM … MrOS Research Group (Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009) 3 44 58
- An unappreciated role for RNA surveillance. (PMID: 14759258) Hillman RT … Brenner SE (Genome biology 2004) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
Products for SHOX2 Gene
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- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for SHOX2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for SHOX2
- VectorBuilder custom plasmid, inducible vectors for SHOX2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SHOX2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 36 available SHOX2 Antibodies ranked by validation data
- Compare Top SHOX2 Antibodies
- antibodies-online: Search results for available SHOX2 related products ranked by validation data
- antibodies-online: Search results for 7 available SHOX2 Proteins ranked by validation data
- Compare Top SHOX2 Proteins
- Search GeneTex for Antibodies for SHOX2
- Search GeneTex for Proteins for SHOX2
- ViGene Biosciences adenoviral particle packaged cDNA for SHOX2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for SHOX2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for SHOX2 gene
- Search ViGene Biosciences for SHOX2
- Santa Cruz Biotechnology (SCBT) Antibodies for SHOX2
- Search Santa Cruz Biotechnology (SCBT) for SHOX2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SHOX2
- Horizon Cell Lines for SHOX2
- genomics-online: cdna clones - Search results for available SHOX2 gene related products
- orf clones - Search results for available SHOX2 gene related products
- genomics-online: gRNA clones - Search results for available SHOX2 gene related products
- genomics-online: primer clones - Search results for available SHOX2 gene related products
- genomics-online: shRNA clones - Search results for available SHOX2 gene related products
Sources for SHOX2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew