Aliases for SGCD Gene
External Ids for SGCD Gene
The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for SGCD Gene
SGCD (Sarcoglycan, Delta (35kDa Dystrophin-Associated Glycoprotein)) is a Protein Coding gene. Diseases associated with SGCD include sgcd-related dilated cardiomyopathy and delta-sarcoglycanopathy. Among its related pathways are Hypertrophic cardiomyopathy (HCM) and Hypertrophic cardiomyopathy (HCM). An important paralog of this gene is SGCZ.
UniProtKB/Swiss-Prot for SGCD Gene
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix