Aliases for SCD Gene
External Ids for SCD Gene
Previous Symbols for SCD Gene
This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Feb 2012]
GeneCards Summary for SCD Gene
SCD (Stearoyl-CoA Desaturase (Delta-9-Desaturase)) is a Protein Coding gene. Diseases associated with SCD include carnitine deficiency, systemic primary and obesity. Among its related pathways are Regulation of Cholesterol Biosynthesis by SREBP (SREBF) and Glucose / Energy Metabolism. GO annotations related to this gene include iron ion binding and stearoyl-CoA 9-desaturase activity. An important paralog of this gene is SCD5.
UniProtKB/Swiss-Prot for SCD Gene
Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA