Aliases for EXOC4 Gene
External Ids for EXOC4 Gene
Previous HGNC Symbols for EXOC4 Gene
Previous GeneCards Identifiers for EXOC4 Gene
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
GeneCards Summary for EXOC4 Gene
EXOC4 (Exocyst Complex Component 4) is a Protein Coding gene. Among its related pathways are Actin Nucleation by ARP-WASP Complex and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein. GO annotations related to this gene include protein N-terminus binding and PDZ domain binding.
UniProtKB/Swiss-Prot for EXOC4 Gene
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.