Aliases for RFX4 Gene
External Ids for RFX4 Gene
Previous GeneCards Identifiers for RFX4 Gene
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]
GeneCards Summary for RFX4 Gene
RFX4 (Regulatory Factor X, 4 (Influences HLA Class II Expression)) is a Protein Coding gene. Among its related pathways are Transcriptional Regulatory Network in Embryonic Stem Cell. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is RFX3.
UniProtKB/Swiss-Prot for RFX4 Gene
May activate transcription by interacting directly with the X-box.