Aliases for RBMY1A1 Gene
External Ids for RBMY1A1 Gene
Previous HGNC Symbols for RBMY1A1 Gene
Previous GeneCards Identifiers for RBMY1A1 Gene
This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2; two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked. [provided by RefSeq, Jul 2008]
GeneCards Summary for RBMY1A1 Gene
RBMY1A1 (RNA Binding Motif Protein, Y-Linked, Family 1, Member A1) is a Protein Coding gene. Diseases associated with RBMY1A1 include partial deletion of y and myotonic dystrophy 2. GO annotations related to this gene include nucleotide binding and mRNA binding. An important paralog of this gene is RBMY1D.
UniProtKB/Swiss-Prot for RBMY1A1 Gene
RNA-binding protein involved in pre-mRNA splicing. Required for sperm development. Acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN. Binds non-specifically to mRNAs.