Aliases for POLD4 Gene
External Ids for POLD4 Gene
This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
GeneCards Summary for POLD4 Gene
POLD4 (Polymerase (DNA-Directed), Delta 4, Accessory Subunit) is a Protein Coding gene. Among its related pathways are Cell Cycle, Mitotic and Cell Cycle, Mitotic. GO annotations related to this gene include DNA-directed DNA polymerase activity.
UniProtKB/Swiss-Prot for POLD4 Gene
Required for optimal DNA polymerase delta activity. May contribute to PCNA-dependent activity of DNA polymerase delta.