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Aliases for ZNF471 Gene

Aliases for ZNF471 Gene

  • Zinc Finger Protein 471 2 3 5
  • EZFIT-Related Protein 1 3 4
  • ERP1 3 4
  • KIAA1396 4
  • Z1971 3

External Ids for ZNF471 Gene

Previous GeneCards Identifiers for ZNF471 Gene

  • GC19P061711
  • GC19P061610
  • GC19P057019
  • GC19P053329

Summaries for ZNF471 Gene

GeneCards Summary for ZNF471 Gene

ZNF471 (Zinc Finger Protein 471) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZFP28.

UniProtKB/Swiss-Prot for ZNF471 Gene

  • May be involved in transcriptional regulation.

Gene Wiki entry for ZNF471 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF471 Gene

Genomics for ZNF471 Gene

Regulatory Elements for ZNF471 Gene

Enhancers for ZNF471 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G055519 1.6 FANTOM5 Ensembl ENCODE 61.5 -987.6 -987634 1.0 HDGF ATF1 ZNF493 ZNF133 YBX1 GLI4 ZNF416 FOS ZNF548 SP3 FIZ1 ZNF471 NAT14 ZNF580 ZNF667 ZNF582-AS1 ZNF667-AS1 ZNF542P U2AF2 ZNF583
GH19G056594 1 ENCODE 40 +87.6 87598 1.4 HDGF PKNOX1 ZNF133 ARID4B SIN3A FEZF1 YBX1 GLI4 ZNF48 YY1 ZNF17 ENSG00000269696 ZNF549 ZNF773 ZNF543 U2AF2 ZFP28 ZNF667 ZNF470 FIZ1
GH19G056403 1.1 ENCODE 27.7 -103.7 -103694 2.0 HDGF CREB3L1 ARNT ARID4B SIN3A DMAP1 YY1 ZNF766 ZNF416 ZNF143 ZNF582-AS1 ZFP28 FIZ1 ZNF543 ZNF471 ZNF264 ZNF542P ZNF470 U2AF2 ENSG00000269696
GH19G056392 1.1 ENCODE 27.6 -114.4 -114387 1.5 CREB3L1 ARNT SIN3A ZNF2 YY1 ZNF766 ZNF416 ZNF143 ZNF207 KLF13 ZNF582-AS1 FIZ1 ZNF543 ZNF471 ZNF264 ZNF542P ZNF470 U2AF2 ENSG00000269696 ZFP28
GH19G055579 1.1 ENCODE 27.5 -926.6 -926644 3.3 HDGF PKNOX1 FOXA2 ARNT WRNIP1 ARID4B SIN3A DMAP1 FEZF1 ZNF2 FIZ1 ZNF471 ZNF542P ZNF470 ENSG00000269696 ZFP28 ZNF583 ZNF582-AS1 ZNF580 LOC729999
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF471 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF471 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000111757 58 1400 ZSCAN4 ZNF133 SIN3A ZNF76 YY1 ETS1 ZNF121 GLIS2 ZNF366 KLF7

Genomic Location for ZNF471 Gene

Chromosome:
19
Start:
56,507,843 bp from pter
End:
56,530,221 bp from pter
Size:
22,379 bases
Orientation:
Plus strand

Genomic View for ZNF471 Gene

Genes around ZNF471 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF471 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF471 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF471 Gene

Proteins for ZNF471 Gene

  • Protein details for ZNF471 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BX82-ZN471_HUMAN
    Recommended name:
    Zinc finger protein 471
    Protein Accession:
    Q9BX82
    Secondary Accessions:
    • B4DF32
    • O75260
    • Q08AD6
    • Q08AD7
    • Q8N3V1
    • Q9P2F1

    Protein attributes for ZNF471 Gene

    Size:
    626 amino acids
    Molecular mass:
    73009 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAC32422.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF471 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF471 Gene

Post-translational modifications for ZNF471 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF471 Gene

No data available for DME Specific Peptides for ZNF471 Gene

Domains & Families for ZNF471 Gene

Gene Families for ZNF471 Gene

Protein Domains for ZNF471 Gene

Suggested Antigen Peptide Sequences for ZNF471 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BX82

UniProtKB/Swiss-Prot:

ZN471_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF471: view

Function for ZNF471 Gene

Molecular function for ZNF471 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF471 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF471: view
genes like me logo Genes that share phenotypes with ZNF471: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF471 Gene

Localization for ZNF471 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF471 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF471 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF471 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IDA --
genes like me logo Genes that share ontologies with ZNF471: view

Pathways & Interactions for ZNF471 Gene

SuperPathways for ZNF471 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF471: view

Pathways by source for ZNF471 Gene

2 Reactome pathways for ZNF471 Gene

Gene Ontology (GO) - Biological Process for ZNF471 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
genes like me logo Genes that share ontologies with ZNF471: view

No data available for SIGNOR curated interactions for ZNF471 Gene

Transcripts for ZNF471 Gene

Unigene Clusters for ZNF471 Gene

Zinc finger protein 471:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF471 Gene

No ASD Table

Relevant External Links for ZNF471 Gene

GeneLoc Exon Structure for
ZNF471
ECgene alternative splicing isoforms for
ZNF471

Expression for ZNF471 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF471 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF471 Gene



Protein tissue co-expression partners for ZNF471 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF471 Gene:

ZNF471

SOURCE GeneReport for Unigene cluster for ZNF471 Gene:

Hs.710590

Evidence on tissue expression from TISSUES for ZNF471 Gene

  • Nervous system(4.2)
  • Muscle(4.1)
  • Pancreas(4.1)
genes like me logo Genes that share expression patterns with ZNF471: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF471 Gene

Orthologs for ZNF471 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF471 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF471 34 35
  • 99.36 (n)
mouse
(Mus musculus)
Mammalia Zfp78 34 16
  • 70.58 (n)
Zfp84 35
  • 45 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia ZNF471 35
  • 66 (a)
OneToOne
Species where no ortholog for ZNF471 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF471 Gene

ENSEMBL:
Gene Tree for ZNF471 (if available)
TreeFam:
Gene Tree for ZNF471 (if available)

Paralogs for ZNF471 Gene

(464) SIMAP similar genes for ZNF471 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF471: view

Variants for ZNF471 Gene

Sequence variations from dbSNP and Humsavar for ZNF471 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
VAR_035583 A colorectal cancer sample
rs1000124736 -- 56,508,616(+) GTATG(C/T)GAGAC intron-variant, utr-variant-5-prime
rs1000129499 -- 56,527,727(+) AGAAT(A/T)CATAC utr-variant-3-prime
rs1000183826 -- 56,527,541(+) AGGAG(C/G)ATGTT utr-variant-3-prime
rs1000185355 -- 56,522,255(+) AGACA(C/T)TGGAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF471 Gene

Variant ID Type Subtype PubMed ID
dgv6591n54 CNV loss 21841781
esv3359099 CNV insertion 20981092
esv3371782 CNV insertion 20981092
nsv1055357 CNV gain 25217958
nsv580387 CNV loss 21841781

Variation tolerance for ZNF471 Gene

Residual Variation Intolerance Score: 77.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.42; 92.79% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF471 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF471

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF471 Gene

Disorders for ZNF471 Gene

Relevant External Links for ZNF471

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF471

No disorders were found for ZNF471 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF471 Gene

Publications for ZNF471 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4 64
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Gene promoter-associated CpG island hypermethylation in squamous cell carcinoma of the tongue. (PMID: 28255813) Bhat S. … Satyamoorthy K. (Virchows Arch. 2017) 3 64
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64

Products for ZNF471 Gene

Sources for ZNF471 Gene

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