Aliases for PTGIR Gene
Aliases for PTGIR Gene
External Ids for PTGIR Gene
- HGNC: 9602
- Entrez Gene: 5739
- Ensembl: ENSG00000160013
- OMIM: 600022
- UniProtKB: P43119
Previous GeneCards Identifiers for PTGIR Gene
- GC19M047767
- GC19M047514
- GC19M051799
- GC19M051815
- GC19M047123
- GC19M043548
Summaries for PTGIR Gene
-
The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq, Jul 2008]
GeneCards Summary for PTGIR Gene
PTGIR (Prostaglandin I2 (Prostacyclin) Receptor (IP)) is a Protein Coding gene. Diseases associated with PTGIR include Acute Erythroid Leukemia and Kidney Papillary Necrosis. Among its related pathways are Platelet homeostasis and Vascular smooth muscle contraction. GO annotations related to this gene include G-protein coupled receptor activity and guanyl-nucleotide exchange factor activity. An important paralog of this gene is PTGER2.
UniProtKB/Swiss-Prot for PTGIR Gene
-
Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
-
Prostanoid receptors are activated by the endogenous ligands prostaglandin (PG) D2, PGE2, PGF2alpha, PGH2, prostacyclin (PGI2) and thromboxane A2. Cyclooxygenase (COX) converts arachidonic acid to PGH2, from which the other prostaglandins are synthesized.
No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PTGIR Gene
Genomics for PTGIR Gene
Regulatory Elements for PTGIR Gene
Enhancers for PTGIR Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around PTGIR on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the PTGIR gene promoter:
Regulatory Element Products
Genomic Location for PTGIR Gene
- Chromosome:
- 19
- Start:
- 46,610,040 bp from pter
- End:
- 46,625,118 bp from pter
- Size:
- 15,079 bases
- Orientation:
- Minus strand
Genomic View for PTGIR Gene
Genes around PTGIR on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.32 by Ensembl
- 19q13.32 by Entrez Gene
- 19q13.32 by HGNC
PTGIR Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PTGIR Gene
Proteins for PTGIR Gene
-
Protein details for PTGIR Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P43119-PI2R_HUMAN
- Recommended name:
- Prostacyclin receptor
- Protein Accession:
- P43119
Protein attributes for PTGIR Gene
- Size:
- 386 amino acids
- Molecular mass:
- 40956 Da
- Quaternary structure:
-
- Interacts (non-isoprenylated C-terminus) with PDZK1.
Protein Expression for PTGIR Gene
Post-translational modifications for PTGIR Gene
- Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C.
- Palmitoylation of either Cys-308 or Cys-311 is sufficient to maintain functional coupling to G(s) and signaling.
- Glycosylation at isoforms=7
- Modification sites at PhosphoSitePlus
Other Protein References for PTGIR Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for PTGIR
- Novus Biologicals Antibodies for PTGIR
- Invitrogen Antibodies for PTGIR
- antibodies-online Antibodies for PTGIR: See all 72
- Search GeneTex for Antibodies for PTGIR
-
Santa Cruz Biotechnology (SCBT) Antibodies for PTGIR
Protein Products
-
OriGene Purified Proteins for PTGIR
- Search Origene for MassSpec and Protein Over-expression Lysates for PTGIR
- Origene Custom Protein Services for PTGIR
- antibodies-online Proteins for PTGIR: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Proteins for PTGIR
No data available for DME Specific Peptides for PTGIR Gene
Domains & Families for PTGIR Gene
Gene Families for PTGIR Gene
- HGNC:
- IUPHAR :
Protein Domains for PTGIR Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for PTGIR Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P43119- Family:
-
- Belongs to the G-protein coupled receptor 1 family.
Function for PTGIR Gene
Molecular function for PTGIR Gene
- GENATLAS Biochemistry:
- protaglandin 12 (prostacyclin) receptor,subtype IP,expressed in the cardiovascular system,G protein coupled receptor superfamily
- UniProtKB/Swiss-Prot Function:
- Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | IEA | -- |
| GO:0005085 | guanyl-nucleotide exchange factor activity | TAS | -- |
| GO:0016501 | prostacyclin receptor activity | IBA | -- |
Phenotypes for PTGIR Gene
- MGI mutant phenotypes for PTGIR:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for PTGIR:
-
- Increased vaccinia virus (VACV) infection
- Increased transferrin (TF) endocytosis
- Increased shRNA abundance (Z-score > 2)
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Decreased shRNA abundance (Z-score < -2)
- Decreased DCP1a protein expression and assembly in processing bodies after arsenite stimulation
Animal Models for PTGIR Gene
- MGI Knock Outs for PTGIR:
-
- Ptgir tm1Sna
Animal Model Products
-
Taconic Biosciences Mouse Models for PTGIR
- Cyagen custom Knockout/knockin (KOKI) mouse models for PTGIR
-
-
ViGene Biosciences lentiviral particle packaged cDNA for PTGIR gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PTGIR gene
- Search ViGene Biosciences for PTGIR
CRISPR Products
-
OriGene CRISPR knockouts for PTGIR
-
Santa Cruz Biotechnology (SCBT) CRISPR for PTGIR
- GenScript: Design CRISPR guide RNA sequences for PTGIR
miRNA Products
- Search ViGene Biosciences for PTGIR
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for PTGIR
- Browse OriGene Inhibitory RNA Products For PTGIR
-
ViGene Biosciences ready-to-package AAV shRNAs for PTGIR gene
Clone Products
-
OriGene ORF clones in human for PTGIR
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for PTGIR
- VectorBuilder custom plasmid, inducible vectors for PTGIR
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PTGIR
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- R&D Systems cDNA Clones for PTGIR
Cell Line Products
-
Horizon Cell Lines for PTGIR
-
ViGene Biosciences adenoviral particle packaged cDNA for PTGIR gene
-
ViGene Biosciences lentiviral particle packaged cDNA for PTGIR gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PTGIR gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for PTGIR Gene
Localization for PTGIR Gene
Subcellular locations from UniProtKB/Swiss-Prot for PTGIR Gene
- Cell membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| cytosol | 5 |
| extracellular | 2 |
| peroxisome | 2 |
| nucleus | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005829 | cytosol | IDA | 20622039 |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0005887 | integral component of plasma membrane | TAS | 7512962 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for PTGIR Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Peptide ligand-binding receptors | ||
| 2 | Eicosanoid ligand-binding receptors | ||
| 3 | Signaling by GPCR | ||
| 4 | Platelet homeostasis | ||
| 5 | Platelet activation | ||
Pathways by source for PTGIR Gene
5 BioSystems pathways for PTGIR Gene
11 Reactome pathways for PTGIR Gene
3 PharmGKB pathways for PTGIR Gene
3 KEGG pathways for PTGIR Gene
1 GeneGo (Thomson Reuters) pathway for PTGIR Gene
2 Qiagen pathways for PTGIR Gene
Interacting Proteins for PTGIR Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | -- |
| GO:0007187 | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | TAS | 7512962 |
| GO:0007189 | adenylate cyclase-activating G-protein coupled receptor signaling pathway | IMP | 20622039 |
| GO:0007267 | cell-cell signaling | TAS | 7512962 |
No data available for SIGNOR curated interactions for PTGIR Gene
Drugs & Compounds for PTGIR Gene
(56) Drugs for PTGIR Gene - From: DrugBank, PharmGKB, ApexBio, DGIdb, FDA Approved Drugs, IUPHAR, HMDB, Tocris, and Novoseek
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Iloprost | Approved, Investigational | Pharma | Full agonist, Agonist, agonist, Target | Others, Prostacyclin (PGI2) analog | 79 | |
| Epoprostenol | Approved | Pharma | agonist, Target | 54 | ||
| Treprostinil | Approved, Investigational | Pharma | Full agonist, Agonist, agonist, Target | 91 | ||
| Dinoprost Tromethamine | Approved, Vet_approved | Pharma | antagonist, Target | 11 | ||
| Misoprostol | Approved | Pharma | antagonist | 304 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
(5) Tocris Compounds for PTGIR Gene
| Compound | Action | Cas Number |
|---|---|---|
| Alprostadil | Prostaglandin. Vasodilator and antiplatelet agent in vivo | 745-65-3 |
| Iloprost | Prostacyclin (PGI2) analog | 78919-13-8 |
| L-798,106 | Potent and highly selective EP3 antagonist | 244101-02-8 |
| Prostaglandin E2 | Major endogenous prostanoid | 363-24-6 |
| U 46619 | Potent, stable thromboxane A2 (TP) receptor agonist | 56985-40-1 |
(21) ApexBio Compounds for PTGIR Gene
| Compound | Action | Cas Number |
|---|---|---|
| (+)-Fluprostenol | 54276-17-4 | |
| (±)-Cloprostenol sodium salt | 55028-72-3 | |
| Alprostadil | 745-65-3 | |
| Bimatoprost | 155206-00-1 | |
| BMY 45778 | Type I IL-1 receptor antagonist | 152575-66-1 |
| Epoprostenol | 61849-14-7 | |
| GW 627368 | 439288-66-1 | |
| Iloprost | 78919-13-8 | |
| L-161,982 | 147776-06-5 | |
| L-655,240 | 103253-15-2 | |
| L-670,596 | 121083-05-4 | |
| L-798,106 | 244101-02-8 | |
| Misoprostol | 59122-46-2 | |
| NS 304 | 475086-01-2 | |
| PF 04418948 | 1078166-57-0 | |
| Prostaglandin F2α | 38562-01-5 | |
| SC 51089 | 146033-02-5 | |
| SC 51322 | 146032-79-3 | |
| Sulprostone | 60325-46-4 | |
| TCS 2510 | 346673-06-1 | |
| U 46619 | selective agonist of prostaglandin H2 (PGH2)/thromboxane A2 (TxA2) (TP) receptor | 56985-40-1 |
Transcripts for PTGIR Gene
mRNA/cDNA for PTGIR Gene
- (3) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (38) Selected AceView cDNA sequences:
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for PTGIR Gene
CRISPR Products
-
OriGene CRISPR knockouts for PTGIR
-
Santa Cruz Biotechnology (SCBT) CRISPR for PTGIR
- GenScript: Design CRISPR guide RNA sequences for PTGIR
miRNA Products
- Search ViGene Biosciences for PTGIR
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for PTGIR
- Browse OriGene Inhibitory RNA Products For PTGIR
-
ViGene Biosciences ready-to-package AAV shRNAs for PTGIR gene
Clone Products
-
OriGene ORF clones in human for PTGIR
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for PTGIR
- VectorBuilder custom plasmid, inducible vectors for PTGIR
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PTGIR
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- R&D Systems cDNA Clones for PTGIR
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | · | 3c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||
| SP2: | - | - | - | ||||||||||||
| SP3: | - | - | - | - | |||||||||||
| SP4: | - | - | - |
Expression for PTGIR Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Skeletal Muscle (Muscoskeletal System)
- Mononuclear Myocytes Hindlimb Ventral Muscle
- Mononuclear Myocytes Sacral Primary Hypaxial Myotome
- Mononuclear Myocytes Thoracic Primary Hypaxial Myotome
- Mononuclear Myocytes Thoracic Primary Epaxial Myotome
- Mononuclear Myocytes Cervical Primary Epaxial Myotome
-
Somite (Muscoskeletal System)
- Mononuclear Myocytes Sacral Primary Hypaxial Myotome
- Mononuclear Myocytes Thoracic Primary Hypaxial Myotome
- Mononuclear Myocytes Thoracic Primary Epaxial Myotome
- Mononuclear Myocytes Cervical Primary Epaxial Myotome
- Mononuclear Myocytes Cervical Epaxial Myotome
-
Limb (Muscoskeletal System)
- Mononuclear Myocytes Hindlimb Ventral Muscle
- Mononuclear Myocytes Forelimb Dorsal Muscles
- Mononuclear Myocytes Hindlimb Dorsal Muscle
- Mononuclear Myocytes Forelimb Ventral Muscles
- Endothelium (Cardiovascular System)
-
Lung (Respiratory System)
mRNA differential expression in normal tissues according to GTEx for PTGIR Gene
This gene is overexpressed in Artery - Aorta (x10.1) and Artery - Coronary (x5.0).
This gene is overexpressed in Peripheral blood mononuclear cells (55.5) and Adipocyte (12.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for PTGIR Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of PTGIR Gene:
PTGIRSOURCE GeneReport for Unigene cluster for PTGIR Gene:
Hs.458324Evidence on tissue expression from TISSUES for PTGIR Gene
- Lung(4.4)
- Pancreas(4.1)
- Nervous system(3.7)
- Heart(3.6)
- Muscle(3.6)
- Kidney(3.3)
- Liver(3.1)
- Intestine(2.9)
- Blood(2.7)
- Stomach(2.7)
Primer Products
-
OriGene qPCR primer pairs and template standards for PTGIR
-
OriGene qPCR primer pairs for PTGIR
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for PTGIR Gene
Orthologs for PTGIR Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | PTGIR 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | PTGIR 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | PTGIR 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Ptgir 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ptgir 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | PTGIR 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | PTGIR 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ptgir 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC561406 34 |
|
||
| ptgir 35 |
|
OneToOne |
- Species where no ortholog for PTGIR was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for PTGIR Gene
(4) SIMAP similar genes for PTGIR Gene using alignment to 5 proteins:
Pseudogenes.org Pseudogenes for PTGIR Gene
Variants for PTGIR Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000026162 | -- | 46,615,647(+) | ACTAC(A/G)GGTGC | intron-variant | |
| rs1000080684 | -- | 46,609,987(+) | TGAGG(C/G)CCCGT | downstream-variant-500B, upstream-variant-2KB, utr-variant-3-prime | |
| rs1000122525 | -- | 46,616,356(+) | TTAGA(A/C)AAAGT | intron-variant | |
| rs1000168088 | -- | 46,623,079(+) | GGGGT(G/T)CAAGC | intron-variant | |
| rs1000368838 | -- | 46,615,375(+) | CCACA(G/T)ATTTT | intron-variant |
Residual Variation Intolerance Score:
52.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.08;
60.92% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for PTGIR Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PTGIR Gene
Disorders for PTGIR Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| acute erythroid leukemia |
|
|
| kidney papillary necrosis |
|
|
| chemical colitis |
|
|
| pulmonary hypertension |
|
|
| chronic pulmonary heart disease |
|
|
Search PTGIR in MalaCards
View complete list of genes associated with diseases
Relevant External Links for PTGIR
No data available for UniProtKB/Swiss-Prot and Genatlas for PTGIR Gene
Publications for PTGIR Gene
- Role of extracellular cysteine residues in dimerization/oligomerization of the human prostacyclin receptor. (PMID: 15194446) Giguere V. … Parent J.-L. (Eur. J. Pharmacol. 2004) 3 4 22 64
- Investigation of a functional requirement for isoprenylation by the human prostacyclin receptor. (PMID: 11895442) Miggin S.M. … Kinsella B.T. (Eur. J. Biochem. 2002) 3 4 22 64
- Chromosomal localization of the human prostanoid receptor gene family. (PMID: 7759114) Duncan A.M. … Adam M. (Genomics 1995) 2 3 22 64
- Structural organization and chromosomal assignment of the human prostacyclin receptor gene. (PMID: 7665161) Ogawa Y. … Narumiya S. (Genomics 1995) 3 4 22 64
- Cloning and expression of a cDNA for the human prostanoid IP receptor. (PMID: 7512962) Boie Y. … Abramovitz M. (J. Biol. Chem. 1994) 3 4 22 64
Products for PTGIR Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- R&D Systems cDNA Clones for PTGIR
- Browse Primary Antibodies
- Browse Proteins and Enzymes
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- Browse Cell Selection and Detection Kits
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- Browse Proteome Profiler Antibody Arrays
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- Custom Antibody ServicesOriGene Antibodies for PTGIR
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for PTGIR
- Search Origene for MassSpec and Protein Over-expression Lysates for PTGIR
- Origene Custom Protein Services for PTGIR
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for PTGIR
- Browse OriGene Inhibitory RNA Products For PTGIR
- OriGene qPCR primer pairs and template standards for PTGIR
- OriGene qPCR primer pairs for PTGIR
- OriGene CRISPR knockouts for PTGIR
- OriGene ORF clones in human for PTGIR
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for PTGIR in any vector
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- GenScript Activity-based Kinase Assay for Compound Screening for PTGIR
- GenScript Custom Assay Services for PTGIR
- GenScript PTGIR - overexpressing Cell Line for Assay
- GenScript Custom overexpressing Cell Line Services for PTGIR
- GenScript: Design CRISPR guide RNA sequences for PTGIR
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Plasmid Preparation
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- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
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- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for PTGIR
- Novus Biologicals proteins and lysates for PTGIR
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Taconic Biosciences Mouse Models for PTGIR
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for PTGIR
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ApexBio compounds for PTGIR
- Addgene plasmids for PTGIR
- antibodies-online Antibodies for PTGIR: See all 72
- antibodies-online Kits for PTGIR: See all 4
- antibodies-online Proteins for PTGIR: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for PTGIR
- Search GeneTex for Proteins for PTGIR
- ViGene Biosciences adenoviral particle packaged cDNA for PTGIR gene
- ViGene Biosciences lentiviral particle packaged cDNA for PTGIR gene
- ViGene Biosciences ready-to-package AAV shRNAs for PTGIR gene
- Search ViGene Biosciences for PTGIR
- Santa Cruz Biotechnology (SCBT) Antibodies for PTGIR
- Search Santa Cruz Biotechnology (SCBT) for PTGIR siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for PTGIR
- Horizon Cell Lines for PTGIR
- Cyagen custom Knockout/knockin (KOKI) mouse models for PTGIR
- VectorBuilder custom plasmid, inducible vectors for PTGIR
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PTGIR
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for PTGIR Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer