Aliases for BRK1 Gene
External Ids for BRK1 Gene
Previous HGNC Symbols for BRK1 Gene
Previous GeneCards Identifiers for BRK1 Gene
GeneCards Summary for BRK1 Gene
BRK1 (BRICK1, SCAR/WAVE Actin Nucleating Complex Subunit) is a Protein Coding gene. Diseases associated with BRK1 include Lung Squamous Cell Carcinoma. Among its related pathways are Innate Immune System and RET signaling. Gene Ontology (GO) annotations related to this gene include protein complex binding and Rac GTPase binding.
UniProtKB/Swiss-Prot for BRK1 Gene
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).