External Ids for PNRC2 Gene
GeneCards Summary for PNRC2 Gene
PNRC2 (Proline-Rich Nuclear Receptor Coactivator 2) is a Protein Coding gene. An important paralog of this gene is PNRC1.
UniProtKB/Swiss-Prot for PNRC2 Gene
Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. Required for UPF1/RENT1 localization to the P-body. Also acts as a nuclear receptor coactivator. May play a role in controlling the energy balance between energy storage and energy expenditure.