External Ids for BMP2K Gene
Previous GeneCards Identifiers for BMP2K Gene
This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for BMP2K Gene
BMP2K (BMP2 Inducible Kinase) is a Protein Coding gene. Diseases associated with BMP2K include Exotropia. Among its related pathways are Transcriptional misregulation in cancer. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is AAK1.
UniProtKB/Swiss-Prot for BMP2K Gene
May be involved in osteoblast differentiation.