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Aliases for C1orf109 Gene

Aliases for C1orf109 Gene

  • Chromosome 1 Open Reading Frame 109 2 3

External Ids for C1orf109 Gene

Previous GeneCards Identifiers for C1orf109 Gene

  • GC01M037817
  • GC01M037919
  • GC01M038147
  • GC01M036264

Summaries for C1orf109 Gene

GeneCards Summary for C1orf109 Gene

C1orf109 (Chromosome 1 Open Reading Frame 109) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf109 Gene

Genomics for C1orf109 Gene

Regulatory Elements for C1orf109 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C1orf109 Gene

Start:
37,681,570 bp from pter
End:
37,692,249 bp from pter
Size:
10,680 bases
Orientation:
Minus strand

Genomic View for C1orf109 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C1orf109 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf109 Gene

Proteins for C1orf109 Gene

  • Protein details for C1orf109 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NX04-CA109_HUMAN
    Recommended name:
    Uncharacterized protein C1orf109
    Protein Accession:
    Q9NX04
    Secondary Accessions:
    • D3DPT1
    • Q8WVD1

    Protein attributes for C1orf109 Gene

    Size:
    203 amino acids
    Molecular mass:
    23373 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C1orf109 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C1orf109 Gene

Proteomics data for C1orf109 Gene at MOPED

Post-translational modifications for C1orf109 Gene

  • Ubiquitination at Lys76
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for C1orf109 Gene

Domains for C1orf109 Gene

Protein Domains for C1orf109 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf109: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf109 Gene

Function for C1orf109 Gene

Gene Ontology (GO) - Molecular Function for C1orf109 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 21516116
genes like me logo Genes that share ontologies with C1orf109: view

Phenotypes for C1orf109 Gene

GenomeRNAi human phenotypes for C1orf109:
genes like me logo Genes that share phenotypes with C1orf109: view

Animal Model Products

CRISPR Products

miRNA for C1orf109 Gene

miRTarBase miRNAs that target C1orf109

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for C1orf109 Gene

Localization for C1orf109 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf109 Gene COMPARTMENTS Subcellular localization image for C1orf109 gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf109 Gene

Pathways for C1orf109 Gene

SuperPathways for C1orf109 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C1orf109 Gene

None

No data available for Pathways by source for C1orf109 Gene

Transcripts for C1orf109 Gene

Unigene Clusters for C1orf109 Gene

Chromosome 1 open reading frame 109:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C1orf109

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf109 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b ^ 3a · 3b · 3c · 3d · 3e · 3f ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d · 6e ^ 7a · 7b · 7c ^ 8a · 8b ·
SP1: - - - - - - - - - -
SP2: - - - - - - - -
SP3: - - - -
SP4: - - -
SP5: - - - - - - - - - - - -
SP6: - -
SP7: - - - - - - - -
SP8: - - - - - - - -
SP9: - - - - - - -
SP10: - - - - - - - - - -
SP11: - - - - - - - - - -
SP12: - - - - - -
SP13: - -
SP14: -
SP15:
SP16: - -
SP17: -

ExUns: 8c ^ 9a · 9b
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:

Relevant External Links for C1orf109 Gene

GeneLoc Exon Structure for
C1orf109
ECgene alternative splicing isoforms for
C1orf109

Expression for C1orf109 Gene

mRNA expression in normal human tissues for C1orf109 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for C1orf109 Gene

SOURCE GeneReport for Unigene cluster for C1orf109 Gene Hs.272673

genes like me logo Genes that share expressions with C1orf109: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C1orf109 Gene

Orthologs for C1orf109 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf109 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf109 35
  • 98.85 (n)
  • 99.01 (a)
C1orf109 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C3H1orf109 35
  • 87.85 (n)
  • 85.71 (a)
MGC166151 36
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C15H1orf109 35
  • 83.42 (n)
  • 78.33 (a)
C1orf109 36
  • 78 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 9930104L06Rik 35
  • 80.95 (n)
  • 78.82 (a)
9930104L06Rik 16
oppossum
(Monodelphis domestica)
Mammalia C1orf109 36
  • 69 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C1orf109 36
  • 63 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1560436 35
  • 80.62 (n)
  • 79.8 (a)
chicken
(Gallus gallus)
Aves C1ORF109 35
  • 54.02 (n)
  • 40.51 (a)
C1orf109 36
  • 37 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C1orf109 36
  • 43 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c1orf109 35
  • 55.72 (n)
  • 45.96 (a)
zebrafish
(Danio rerio)
Actinopterygii C19H1orf109 36
  • 37 (a)
OneToOne
c1orf109 35
  • 49.74 (n)
  • 37.95 (a)
Species with no ortholog for C1orf109:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf109 Gene

ENSEMBL:
Gene Tree for C1orf109 (if available)
TreeFam:
Gene Tree for C1orf109 (if available)

Paralogs for C1orf109 Gene

No data available for Paralogs for C1orf109 Gene

Variants for C1orf109 Gene

Sequence variations from dbSNP and Humsavar for C1orf109 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs14307 -- 37,681,934(+) AAAAA(A/T)TTGTG utr-variant-3-prime
rs476368 -- 37,688,150(+) ctccc(A/G)ggtcc intron-variant
rs478140 -- 37,688,330(+) gccat(A/G)agcca intron-variant
rs494132 -- 37,684,873(+) TTGAG(A/G)GAAGA intron-variant
rs497001 -- 37,685,193(+) TTTTT(G/T)GGGGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf109 Gene

Variant ID Type Subtype PubMed ID
nsv834746 CNV Loss 17160897
nsv819737 CNV Loss 19587683

Relevant External Links for C1orf109 Gene

HapMap Linkage Disequilibrium report
C1orf109

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf109 Gene

Disorders for C1orf109 Gene

No disorders were found for C1orf109 Gene.

No data available for UniProtKB/Swiss-Prot for C1orf109 Gene

Publications for C1orf109 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Identification and characterization of a novel gene, c1orf109, encoding a CK2 substrate that is involved in cancer cell proliferation. (PMID: 22548824) Liu S.S. … Li Y. (J. Biomed. Sci. 2012) 2 3
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  5. Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. (PMID: 24144296) Cheng C.Y. … Baird P.N. (Am. J. Hum. Genet. 2013) 3

Products for C1orf109 Gene

Sources for C1orf109 Gene

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