Aliases for POU2AF1 Gene
External Ids for POU2AF1 Gene
Previous GeneCards Identifiers for POU2AF1 Gene
GeneCards Summary for POU2AF1 Gene
POU2AF1 (POU Class 2 Associating Factor 1) is a Protein Coding gene. Diseases associated with POU2AF1 include primary biliary cirrhosis and hodgkin's lymphoma, lymphocytic depletion. GO annotations related to this gene include transcription coactivator activity and transcription cofactor activity.
UniProtKB/Swiss-Prot for POU2AF1 Gene
Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers