Aliases for POLRMT Gene
External Ids for POLRMT Gene
Previous GeneCards Identifiers for POLRMT Gene
This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. [provided by RefSeq, Jul 2008]
GeneCards Summary for POLRMT Gene
POLRMT (Polymerase (RNA) Mitochondrial (DNA Directed)) is a Protein Coding gene. Diseases associated with POLRMT include essential thrombocythemia. Among its related pathways are Gene Expression and RNA Polymerase I Promoter Opening. GO annotations related to this gene include DNA-directed RNA polymerase activity.
UniProtKB/Swiss-Prot for POLRMT Gene
DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates.