Aliases for ACP5 Gene
External Ids for ACP5 Gene
Previous GeneCards Identifiers for ACP5 Gene
This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. [provided by RefSeq, Aug 2008]
GeneCards Summary for ACP5 Gene
ACP5 (Acid Phosphatase 5, Tartrate Resistant) is a Protein Coding gene. Diseases associated with ACP5 include Spondyloenchondrodysplasia With Immune Dysregulation and Bone Giant Cell Tumor. Among its related pathways are RANK Signaling in Osteoclasts and Metabolism of water-soluble vitamins and cofactors. GO annotations related to this gene include hydrolase activity and ferric iron binding.
UniProtKB/Swiss-Prot for ACP5 Gene
Involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias.