Aliases for KLF13 Gene
External Ids for KLF13 Gene
Previous GeneCards Identifiers for KLF13 Gene
KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).[supplied by OMIM, Mar 2008]
GeneCards Summary for KLF13 Gene
KLF13 (Kruppel-Like Factor 13) is a Protein Coding gene. Diseases associated with KLF13 include 15q13.3 microdeletion. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is KLF2.
UniProtKB/Swiss-Prot for KLF13 Gene
Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells.